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CSO exam 2023 > Medications > Flashcards

Medications Flashcards

1
Q

Ifosfamide (Ifex) disease sites

A

bladder, cervix, germ cell, H&N, lung, NHL, sarcomas

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2
Q

Ifosfamide (Ifex) side effects

A

BLADDER TOXICITY, myelosuppression, N/V, anorexia, SIADH, neurotoxicity, alopecia

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3
Q

Mechlorethamine (mustine, nitrogen mustard) disease sites

A

CLL, CML, HD, NHL, mycosis fungoides, breast, lung

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4
Q

Mechlorethamine (mustine, nitrogen mustard) side effects

A

Myelosuppression, N/V, hyperuricemia, pain/inflammation @ injection site, alopecia

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5
Q

Melphalan (Alkeran) disease sites

A

breast, ovarian, MM, HCT, polycythemia vera, neuroblastoma

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6
Q

Melphalan (Alkeran) side effects

A

myelosuppression, N/V/C, mucositis, hypersensitivity infusion reaction

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7
Q

Oxaliplatin (Eloxatin) disease sites

A

Colorectal, pancreatic

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8
Q

Oxaliplatin (Eloxatin) side effects

A

myelosuppression, N/V/D, neurotoxocity (sensitivity to cold), hepatic toxicity

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9
Q

Temozolomide (Temodal) disease sites

A

astrocytomas, glioblastoma

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10
Q

Temozolomide (Temodal) side effects

A

myelosuppression, N/V/C, fatigue, headache, hepatic toxicity, photosensitivity, rash

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11
Q

Thiotepa (Thioplex) disease sites

A

bladder, breast, ovarian, HD, NHL

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12
Q

Thiotepa (Thioplex) side effects

A

myelosuppression, N/V, mucositis, renal toxicity, skin changes

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13
Q

Antimetabolites

A

interfere with DNA synthesis by acting as false metabolites ; incorporated into the DNA strand or block essential enzymes

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14
Q

Azaxcitidine (Vidaza) disease sites

A

CML, myelodysplastic syndrome (MDS)

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15
Q

Azaxcitidine (Vidaza) side effects

A

myelosuppression, N/V/C/D, fatigue, hypokalemia, renal toxocity

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16
Q

Capecitabine (Xeloda) disease sites

A

colon, esophageal, pancreatic, rectal, (metastatic) breast

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17
Q

Capecitabine (Xeloda) side effects

A

myelosuppression, N/V/D, fatigue, increased bilirubin, hand and foot syndrome (needs heavy lotion for rash)

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18
Q

Cytarabine (ARA-C) disease sites

A

ALL, APL, AML, CML, HNL

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19
Q

Cytarabine (ARA-C) side effects

A

myelosuppression, N/V > 1mg/m2, mucositis, anorexia, acute pancreatitis, neurotoxicity (lethargy, confusion), hepatic toxicity, pulmonary toxicity, conjunctivitis, keratitis

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20
Q

Fludarabine (Fludara) disease sites

A

CLL, HNL, acute leukemias

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21
Q

Fludarabine (Fludara) side effects

A

myelosuppression, N/V/D, neurotoxicity, rash

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22
Q

Fluorouracil (5FU) disease sites

A

breast, colon, rectal, cervical, GI tract, H&N, pancreatic, ovarian, stomach, unknown primary, hepatobiliary, neuroendocrine, thymic

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23
Q

Fluorouracil (5FU) side effects

A

myelosuppression, N/V/D, mucositis, hand and foot syndrome, cardiac toxicity, photosensitivity, dysgeusia

Nutrient of interest: B6 (hand foot syndrome)

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24
Q

Gemcitabine (Gemzar) disease sites

A

bladder, breast, lung, ovarian, pancreatic, HNL, sarcoma

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25
Q

Gemcitabine (Gemzar) side effects

A

myelosuppression, N/V, pulmonary toxicity, rash, FLU-LIKE SYMPTOMS

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26
Q

Hydroxyurea (Hydrea) disease sites

A

CML, blood disorders, H&N, ovarian

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27
Q

Hydroxyurea (Hydrea) side effects

A

myelosuppression, N/V/D, mucositis, darkening/thickening of the nails

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28
Q

Mercaptopurine (6-MP) disease sites

A

ALL, APL, lymphoma, ulcerative colitis, Crohn’s disease

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29
Q

Mercaptopurine (6-MP) side effects

A

myelosuppression, N/V/D, mucositis, hepatic toxicity, hyperuricemia

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30
Q

Methotrexate (MTX) disease sites

A

bladder, breast, H&N, HNL, ALL, osteosarcoma, rheumatoid arthritis

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31
Q

Methotrexate (MTX) side effects

A

myelosuppression, nausea, mucositis, oral + GI ulcerations, renal toxicity, hepatic toxicity, photosensitivity

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32
Q

Methotrexate (MTX) usually requires what supplements?

A

folic acid and B12 to reduce side effects

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33
Q

Pemetrexed (Alimta) disease sites

A

mesothelioma, lung

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34
Q

Pemetrexed (Alimta) side effects

A

myelosuppression, N/V/D, fatigue, rash

Nutrients of interest: folic acid, vit B12

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35
Q

Pemetrexed (Alimta) usually requires what supplements?

A

folic acid and B12 to reduce side effects

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36
Q

Thioguanine (6-TG) disease sites

A

AML, CML

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37
Q

Thioguanine (6-TG) side effects

A

myelosuppression, N/V/D, mucositis, hepatic toxicity, renal toxicity, rash

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38
Q

Bleomycin (Blenoxane) disease sites

A

HD, HNL, H&N, SCC of the skin, cervical, vulva, testes, melanoma, malignant pleural effusions

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39
Q

Bleomycin (Blenoxane) side effects

A

PULMONARY TOXICITY, renal toxicity, hyperpigmentation, skin/nail changes, hypersensitivity infusion reaction

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40
Q

Dactinomycin (Actinomycin D) disease sites

A

Ewing sarcoma, rhabdomyosarcoma, Wilms tumor, testicular

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41
Q

Dactinomycin (Actinomycin D) side effects

A

myelosuppression, N/VD, mucositis, anorexia, alopecia

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42
Q

Mitomycin-C (Mutamycin) disease sites

A

anal, bladder, breast, esophageal, H&N, lung, pancreatic, stomach

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43
Q

Mitomycin-C (Mutamycin) side effects

A

myelosuppression, N/V/D, mucositis, anorexia, pulmonary toxicity, renal toxicity, alopecia

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44
Q

Cisplatin disease sites

A

Lung
Bladder
Ovarian
Testicular
H&N
Esophageal
Neuroblastoma

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45
Q

Cisplatin side effects

A

N/V, increased fluid needs, check renal function/electrolytes, SIADH, B/C/D, dyusgeusia, HLD/CVD risk

May cause hypoalbuminemia
Milk Thistle may benefit
Tumeric may benefit (fatty foods, black pepper)
Omega 3 may benefit

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46
Q

Carboplatin disease sites

A

Ovarian
Fallopian tube
NSCLC

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47
Q

Carboplatin side effects

A

N/V, renal toxicity

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48
Q

Abraxane (Paclitaxel) disease sites

A

Breast
Lung
Pancreatic
Second line breast

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49
Q

Abraxane (Paclitaxel) side effects

A

N/V/D, mucositis, LE edema, elevated LFT’s

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50
Q

Adriamycin (Doxorubicin) disease sites

A

Burkitt’s Lymphoma
Hodgin’s Lymphoma
Wilm’s tumor
Acute Lymphoid Leukemia
Acute Myeloid Leukemia

51
Q

Adriamycin (Doxorubicin) side effects

A

N/V/D, loss of appetite, mucositis

CoQ10 limits renal/cardiac toxicity
Theanine may benefit
Omega 3 may benefit

52
Q

Alemtuzumab (Campath) disease sites

53
Q

Alemtuzumab (Campath) side effects

A

hypotension, anemia
Used for B cell lymphoma

54
Q

Anastrozole (Arimidex) disease sites

A

Breast (post menopausal)

55
Q

Anastrozole (Arimidex) side effects

A

N/V/C/D, hot flashes, thromboembolic issues

56
Q

Aromasin (Exemestane) disease sites

A

Breast (post menopausal)

57
Q

Aromasin (Exemestane) side effects

A

hot flashes, thromboembolic issues, N/V

58
Q

Avastin (Bevacizumab) disease sites

A

Cervical
Glioblastoma
Liver
Ovarian
Fallopian tube

59
Q

Avastin (Bevacizumab) side effects

A

N/V/C/D, mucositis

60
Q

Cetuximab (Erbitux) disease sites

A

Colorectal
H&N

61
Q

Cetuximab (Erbitux) side effects

A

Causes: N/C/D, loss of appetite, decreased Mg, cardiac/respiratory distress

Nutrients of interest: Mg/Ca

62
Q

Carmustine (BiCNU) disease sites

A

Multiple Myeloma
Brain
Hodgkin’s disease
Non-Hodgkin’s Lymphoma

63
Q

Carmustine (BiCNU) side effects

64
Q

Cyclophosphamide (Cytoxan) disease sites

A

Multiple Myeloma
Leukemia
Hodgkin’s Lymphoma
Burkitt’s Lymphoma

65
Q

Cyclophosphamide (Cytoxan) side effects

A

N/V < 1500 mg/m2, SIADH

66
Q

Dacarbazine (DTIC-Dome) disease sites

A

Skin – Melanoma (metastatic)
Hodgkin’s disease

67
Q

Dacarbazine (DTIC-Dome) side effects

A

N/V, flu like s/s

68
Q

Daunorubicin (Cerubidine) disease sites

69
Q

Daunorubicin (Cerubidine) side effects

70
Q

Epirubicin (Ellence) disease sites

71
Q

Epirubicin (Ellence) side effects

72
Q

Etoposide (Toposar) disease sites

73
Q

Etoposide (Toposar) side effects

A

May enhance Coumadin
N/V, hypersensitivity

74
Q

Erythropoietin

A

A hormone that your kidneys naturally make to stimulate the production of RBC
May be given to patients for fatigue

75
Q

Faslodex (Fulvestrant) disease sites

76
Q

Faslodex (Fulvestrant) side effects

A

N/V, hot flashes

77
Q

Femara (Letozole) disease sites

78
Q

Femara (Letozole) side effects

A

hot flashes, thromboembolic issues

79
Q

Herceptin (Traztuzumab) disease sites

A

Breast
Stomach
Esophageal

80
Q

Herceptin (Traztuzumab) side effects

A

N/V/D, flu like s/s, anemia

Oleic Acid may help – found in avocado, nuts/seeds, oils

81
Q

Idarubicin (Idamycin) disease sites

82
Q

Idarubicin (Idamycin) side effects

A

N/V

Theanine may benefit

83
Q

Irinotecan (Camptosar) disease sites

A

Colorectal

84
Q

Irinotecan (Camptosar)

A

N/V/D, loss of appetite

Omega 3 may benefit

85
Q

Kadcyla (Ado-trastuzumab emtansine) disease sites

86
Q

Kadcyla (Ado-trastuzumab emtansine) side effects

A

Toxic to cardiac, liver, lung, causes constipation, thrombocytopenia

87
Q

Lupron (leuprolide) disease sites

88
Q

Lupron (leuprolide) side effects

89
Q

Mechlorethamine (Valchlor) disease sites

90
Q

Mechlorethamine (Valchlor) side effects

A

N/V
Used on the skin

91
Q

Mitomycin (Mutamycin) disease sites

A

Stomach
Pancreatic

92
Q

Mitomycin (Mutamycin) side effects

A

N/V/D, loss of appetite, mucositis, SOB,
renal/lung toxicity, discolored urine

93
Q

Megace side effects

A

wt gain, fluid retention

94
Q

Navelbine (Vinoelbine) disease sites

95
Q

Navelbine (Vinoelbine) side effects

A

N/V/C, loss of appetite

96
Q

Oncovin (Vincristine) disease sites

A

Lymphoma
Wilm’s tumor

97
Q

Oncovin (Vincristine) side effects

A

constipation, renal toxicity

98
Q

Oxaliplatin (Eloxatin) disease sites

A

Colorectal

99
Q

Oxaliplatin (Eloxatin) side effects

A

cold sensitivity, N/V/D

Nutrients of interest: Mg/Ca

100
Q

Panitumumab (Vectibix) disease sites

A

Colorectal

101
Q

Panitumumab (Vectibix) Nutrient of interest

102
Q

Paclitaxel (Taxol) disease sites

A

Breast
Ovarian
Esophageal
Lung
Cervical
Pancreatic

103
Q

Paclitaxel (Taxol) side effects

A

N/V/D, mucositis, decreased Mg/K+/vit D, fatigue

May cause hypoalbuminemia
Omega 3 may benefit
Selenium may benefit

104
Q

Pertuzumab (Perjeta) disease sites

105
Q

Pertuzumab (Perjeta) side effects

A

N/V/C/D, mucositis

106
Q

Sorafenib (Nexavar) disease sites

A

Kidney
Liver
Thyroid

107
Q

Sorafenib (Nexavar) side effects

A

N/V/D, loss of appetite

108
Q

Tacrolimus (Prograf) disease sites

A

Kidney
Heart
Liver
Lung
(transplants)

109
Q

Tacrolimus (Prograf) nutrients of interest

110
Q

Taxotere (Docetaxel) disease sites

A

Breast
Lung
Prostate
Stomach
H&N

111
Q

Taxotere (Docetaxel) side effects

A

N/V, fluid retention

112
Q

Tamoxifen (Nolvadex, Soltamox) disease sites

113
Q

Tamoxifen (Nolvadex, Soltamox) side effects

A

hot flashes, thromboembolic issues, menstrual s/s, fluid retention

114
Q

Topotecan (Hycamtin) disease sites

A

Ovarian
Lung
Cervical

115
Q

Topotecan (Hycamtin) side effects

A

N/C/D, loss of appetite, mucositis

116
Q

Velcade (Bortezomib) disease sites

A

Multiple Myeloma
Mantle Cell Lymphoma

117
Q

Avoid what with Velcade (Bortezomib)

A

Avoid green tea

118
Q

Vincristine (Oncovin) disease sites

A

Lymphoma
Wilm’s tumor

119
Q

Vincristine (Oncovin) side effects

A

constipation

Omega 3 may benefit

120
Q

Zoladex (Goserelin) disease sites

A

Prostate
Breast

121
Q

Zoladex (Goserelin) side effects

122
Q

Zometa (Zoledronic acid) nutrients of interest

A

Ca/Vit D
Used to treat hypercalcemia that may occur with cancer

123
Q

Busulfan (Busulfex) disease sites

124
Q

Busulfan (Busulfex) side effects

A

Hepatic toxicity, pulmonary toxicity (get pulm tests before)

CSO exam 2023 (2 decks)

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