Medication Treatments Flashcards
Scz 1st line
- AP. No established clinical superiority of one.
- Consider LAI early.
Scz trial
- If no response at 4 weeks, change medication.
- If a partial response, r/a at 8 weeks unless sig interval change.
- Trial: 6 weeks at optimized dose.
- Following resolution of (+) sx, tx should ctn for 18 months.
Mania monotherapy 1st line
DVP, Li
Abilify, Asenapine, Seroquel, Risperidone, Paliperidone, Cariprazine
Mania combo therapy 1st line
DVP/Li + Abilify/Asenapine/Risperidone/Seroquel
Bipolar I depression 1st line, mono and combo
- Mono: Seroquel, Li, Latuda
(adj) Lamotrigine - Combo: Li/DVP + Latuda
Bipolar I maintenance monotherapy 1st line
DVP, Li, Lamotrigine
Abilify (po/IM), Asenapine, Seroquel
Bipolar I maintenance combo therapy 1st line
DVP/Li + Seroquel/Abilify
Bipolar II hypomania
- No specific recommendations. Refer to mania.
Bipolar II depression 1st/2nd line
- First line: Seroquel
- Second line: Li, Lamotrigine, Bupropion (adj), Sertraline, Venlafaxine, ECT (level 3)
Bipolar II maintenance 1st line
Seroquel (level 1)
Li, Lamotrigine (level 2)
Bipolar II maintenance 2nd line
Venlafaxine (level 2)
GAD 1st line
- Escitalopram, Paroxetine (+CR), Sertraline
- Venlafaxine XR, Duloxetine
- Pregabalin
- Aglomelatine
Social anxiety disorder 1st line
- Escitalopram, Fluvoxamine CR, Paroxetine (CR), Sertraline
- Venlafaxine XR
- Pregabalin
- If performance only, consider beta blocker
Panic disorder/Agorophobia 1st line
- Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine (CR), Sertraline
- Venlafaxine XR
Specific phobia 1st line
- Medications generally not recommended
MDD 1st line
- Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline
- Bupropion
- Duloxetine, Venlafaxine, Desvenlafaxine, Milnicepran
- Mirtazapine
- Vortioxetine
- Aglomelatine
- Minaserin
OCD 1st line
- Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline
MDE 2nd line
- TCAs
- Trazodone
- Seroquel
- Vilazadone
- Moclobemide
- Selegiline transdermal
- Levomilnicepram
MDD with anxious distress
Use a med with efficacy in GAD (level 4)
MDD with catatonic features
Benzos (level 3)