Medication SEs Flashcards
myocardial ischemia, myelosuppression
5-FU
reversible pneumonitis, hepatic fibrosis
Methotrexate
neuropathy, SIADH
vincristine
interstitial fibrosis
bleomycin
cardiomyopathy
doxorubicin, trastuzumab
HUS, blue green urine
mitomycin
hemorrhagic cystitis, bladder cancer
cyclophosphamide (can give mesna)
neuropathy, bradycardia
paclitaxel
anal pruritus, HUS, flu, rash
gemcitabine
hot flashes, thromboemboli, endometrial cancer
tamoxifen
impotence, transient cancer flare, osteoporosis
GnRH agonists (Lupron, Zoladex)
decreased WBCs, myelosuppression
hydroxyurea
myelosuppression, hypotension, weakness, alopecia
etoposide
nephrotoxic, ototoxic, neuropathy
cisplatin
flu like symptoms, LFTs increase, arthralgias, hypo/hyperthyroidism
interferon alpha
capillary leak syndrome, erythema
IL-2 (āLā for leukin)
rash, vitiligo, worsening of autoimmune diseases
PD1, PDL1, CTLA