CLL

Question 1

what reduces the risk of infections in patients with chronic lymphocytic leukemia with documented hypogammaglobulinemia?

Answer 1

Intravenous immunoglobulin G replacement therapy (therefore, measure immunoglobulin levels in patients with recurrent PNA)

Question 2

1. What type of anemia is common in patients with CLL?

2. What test can confirm the diagnosis?

Answer 2

1. Autoimmune hemolytic anemia

2. A direct antiglobulin (Coombs) test can confirm the diagnosis and guide treatment.

Question 3

a deletion of chromosome 17p is concerning because?

Answer 3

it is associated with a short median survival (less than 3 years)