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GNURS625 > Medication Dosages > Flashcards

Medication Dosages Flashcards

1
Q

Etomidate

A 
Etomidate (Amidate)
Class: GABA mimetic
Induction Dose: 0.3-0.6mg/kg.
ECTs: 0.2-0.3 mg/kg 
Onset: 30-40 seconds
Peak: 1 minute
Duration: 3-10 minutes
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2
Q

Propofol

A 
Propofol (Isopropylphenol)
Class: Anesthetic
amnestic drug.
Doses: (Recommended induction doses by the ASA) 
Induction for 18-65yo with status 1-2: 2.0 to 2.5 mg/kg
Induction for >65yo: 1.0 to 1.5 mg/kg
Onset: 30-40 seconds
Peak: 1 minute
Duration: 3-10 minutes
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3
Q

Ketamine

A 
Class: Phencyclidine derivative.
Induction Dose: 1-2mg/kg IV 6-13mg/kg IM Peds IM: 6-13mg/kg IM
Peds IV 1-2mg/kg IM
Onset: 30secs
Peak: 3-5 minutes
Duration: 8-15 minutes
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4
Q

Fentanyl

A

Doses:
For analgesia 1-2mcg/kg per dose initially (most popular).
50-150mcg/kg alone to produce surgical analgesia.
Induction (hearts): usually 10-20cc of Fentanyl.
Peds: 1-2mcg/kg
Half-life: 2-4 hours
100mcg Bolus duration of analgesia: 30-60 mins

No fentanyl for RSI - relaxes sphincter

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5
Q

Succinylcholine (Anectine, Quelicin)

A 
Class: Depolarizing Muscle Relaxant
It's basically 2 Acetylcholine molecules bound together
Muscle relaxant of choice for difficult airways.
Doses:
IV: 0.5-1.0mg/kg
RSI: 
Onset: 30-60
Duration: 3-5 minutes.

Roc (5mg), lido, propofol, succs if usings to control for fasciculations.

Fentanyl in between roc & lido if giving

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6
Q

Sugammadex

A

Class: Selective Muscle Relaxant (steroidal) binding and reversal agent. Works only for Rocuronium, Vecuronium and Pancuronium.

Dose: TOF twitch-dependent

Routine dose with 2 TO4 twitches: 2 mg/kg - reversal time is 1.5 minutes.

Zero twitches with 1-2 post-titanic twitch: 4 mg/kg - reversal time 3 minutes.

Emergency reversal (3 minutes after Roc max intubating does (1.2 mg/kg): 16 mg/kg - reversal time 3 minutes. There are no data to support the use of sugammadex for immediate reversal following vecuronium induced blockade
Administered as a single rapid bolus.
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7
Q

Rocuronium

A 
Class: NDMD (Intermediate Acting)
Subclass: Monoquaternary aminosteroid.
Doses
ED95: 0.3mg/kg
Intubating dose: 0.6-1.2mg/kg
RSI dose:1-1.2mg/kg
Redose: 0.1mg/kg
Peds (IM): 1-1.8mg/kg
Drip: 3-12mcg/kg/min
Onset: 1-2 minutes 
Peak: 60-90 seconds
Duration: 20-35 minutes

Roc (5mg), lido, propofol, succs if usings to control for fasciculations.

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8
Q

Neostigmine

A 
Class: Anticholinesterase
Dose: 0.02-0.08mg/kg (0.05mg/kg is popular)- maximum is 5 mg.
2 TOF twitches Fade ++++: 0.07mg/kg
3-4 TOF twitches Fade +++ 0.04mg/kg
Robinul (Glycopyrrolate)- give 0.2mg per 1mg of Neostigmine to prevent Bradycardia.
Onset: 1-5 minutes
Peak: 7-14 minutes
Duration: 30-60 minutes
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9
Q

Cisatracurium

A 
Class: NDMD (Intermediate Acting)
Subclass: Benzylisoquiniline 
The muscle relaxant of choice for hepatic or renal dysfunction. because it uses Hydrolysis and Hoffman Elimination.
Intubating dose: 0.1-0.2mg/kg 
Calculate doses with ideal body weight, not real body weight.
ED95: 50mcg/kg (0.05mg/kg)
Onset: 1.5-5 minutes 
Peak: 3-5 minutes 
Duration: 25-35 minutes
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10
Q

Vecuronium

A 
Class: NDMD (Intermediate Acting)
Subclass: Monoquaternary aminosteroid
ED95: 50mcg/kg (0.05mg/kg)
Intubating dose: 0.08-0.1 mg/kg (most just say 0.1mg/kg)
Peds IV: 0.1mg/kg
Peds IM: 1-1.8mg/kg (Peds) IM
Drip: 0.8-1.2 mcg/kg/min
Onset: 3-5 minutes 
Peak: 3-5 minutes 
Duration: 20-35 minutes
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11
Q

Robinul (Glycopyrrolate)

A 
Class: Anticholinergic
Quatenary Ammonium
Onset: Immediate 
Doses:
With Reversal: 0.01-0.02mg/kg IV or (0.2mg per 1mg of Neostigmine).
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12
Q

Lidocaine

A

Class: Class 1B anti-arrhythmic agent (membrane stabilizing and mild.)
Blunts dysrhythmias and tachycardia. Dose:1-1.5mg/kg IV
Dosage should not exceed 300 mg/hr IV.
Onset 45-90 seconds
Half-Life: Initial 7-30minutes, terminal 1.5-2 hours

1mg/kg pre-induction

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13
Q

Versed (Midazolam)

A 
Class: Benzodiazepine.
Dosing:
Standard Pre-op: 2-5mg IV.
Standard sedation: 1-2.5mg.
Induction: 0.2-0.6mg/kg.
Onset: 30-60 seconds
Peak: 3-5 minutes
Duration: 30-60 minutes
Elimination Halftime: 1-4hr
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14
Q

Sevoflurane

A 
MAC (30-55yo): 1.8%
MAC (>60yo): 1.7%
Peds MAC: 2.3-3.5%
Vapor Pressure: 170
Prevents Recall: 0.5 MAC
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15
Q

Nitrous Oxide

A

Class: Inhalation Agent
Blood: Gas Partition Coefficient: 0.46. Almost as fast acting as Desflurane.
Poor blood solubility so has a fast onset/offset.
Mac: 104%.

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16
Q

Isoflurane (Forane)

A 
Halogenated methyl ethyl ether
The slowest and cheapest Inhalation agent we use.
Color Code: Purple
Blood: Gas Partition Coefficient:1.46.
MAC (30-55yo): 1.17%
MAC (> 60yo): 1.0
Peds MAC: 0.8-1.2
Vapor Pressure: 240
Prevents Recall: 0.4 MAC
17
Q

Desflurane (Suprane)

A 
fluorinated methyl ether ether. 
The fastest inhalation agent we use.
Color Code: Black
MAC:(30-55yo): 6.6%
MAC: (>60 yo): 5-6%
Peds MAC: 8-9%
Blood:Gas Partition Coefficient: 0.42.

GNURS625 (3 decks)

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