Medication Administration chp 25 Flashcards
the transmission of medications from the location of administration to the bloodstream
absorption
Oral: barriers to absorption
medications must pass through the layer of epithelial cells that line the GI tract
Subcu and IM: barriers to absorption
capillary walls have large spaces between cells. Therefore, there is no sign. barrier
Highly soluble medications have rapid absorption times between __ to ___
10-30 mins
sites with high blood perfusion have ____
rapid absorption
IV absorption pattern
immediate: enters blood directly
complete: reaches blood in its entirety
The transportation of medications to sites of action by bodily fluids
distribution
Factors influencing distribution: (3)
circulation
permeability of the cell membrane
plasma protein binding
changes medication into less active forms or inactive forms by action of enzymes.
metabolism (biotransformation)
A ___ ___ level is in the therapeutic range when it is effective and not toxic.
plasma medication
Short half- lives leave the body in:
4-8 hours
when giving short-dosing intervals or MEC drops between doses you can
- give medications at longer intervals without a loss of therapeutic effects
- medications take a longer time to reach a steady state
the interactions between medications and target cells, body systems, and organs to produce effects.
Pharmacodynamics
oral or enteral medications should be given __ - ___ before meals and ___ after meals
30 mins-1hr
2 hrs
kids are dosed based on their body weight until they reach ____kg
50kg
Secondary effects of Pharmacodynamics are:
Unintended
non therapeutic
usually: predictable, harmless, or harmful
Harmful, unintended, usually unpredicted reactions to a drug administered at the normal dosage.
Adverse reactions
When the immune system identifies medication as a foreign substance that should be neutralized or destroyed
allergic reaction
POLAR OPPOSITE of what you would expect to happen when giving a drug. ( Benadryl can make you wired when its really supposed to make you tired)
Idiosyncratic reaction
Drug Interactions:
when drugs are mixed and cause deterioration of one or both drugs. (Aderol mixed with something else in IV.. forms precipitate)
Incompatible drugs
Components of the medication order/prescription. Must be on there ( 6)
- client’s full name
- date and time
- name of med
- dosage size, frequency, # of doses
- route of administration
- signature of prescriber & DEA #
Common Medication errors are caused by:
- lack of knowledge or info
- faulty communication
- equipment errors
- calculation and measurement errors
- similar names of medication OR patient names
- nurse fatigue, distraction, interrupted
What’s the first thing you do if you commit a med errors?
- ASSESS THE PT!
- Report findings to the primary care provider!
- Report it to your preceptor or charge nurse
When do yo perform the 3 med checks?
- Before you pour- at the med cart compare the label and MAR
- After you pour- verify the label against MAR
- At bedside- before you administer