Medically Compromised Flashcards
Clotting factor deficiencies
Hemophilia A and B
Von Willebrand’s
Primary hemostasis
Platelet plug
Secondary hemostasis
fibrin clot
Decrease in Factor 8
Hemophilia A
Decrease in Factor 9
Hemophilia B
This binds to Factor 8, which then binds to platelets to activate the coagulation cascade.
vWF
This activates Factor 10 in the INTRINSIC pathway.
Factor 8
X-linked recessive disorder.
Hem A and B
Only males are affected by this disease.
Hem A and B
Known as Christmas Disease
Hemophilia B
Needed for platelet adhesion.
vWF
Can be autosomal dominant or acquired.
von Willebrand’s disease
This is prolonged in Hemophilia A and B, and von Willebrand’s.
Partial Thromboplastin Time
Test of the intrinsic pathway.
Partial Thromboplastin Time
Normal Partial Thromboplastin Time
24-38 seconds