Medically Compromised Flashcards
Clotting factor deficiencies
Hemophilia A and B
Von Willebrand’s
Primary hemostasis
Platelet plug
Secondary hemostasis
fibrin clot
Decrease in Factor 8
Hemophilia A
Decrease in Factor 9
Hemophilia B
This binds to Factor 8, which then binds to platelets to activate the coagulation cascade.
vWF
This activates Factor 10 in the INTRINSIC pathway.
Factor 8
X-linked recessive disorder.
Hem A and B
Only males are affected by this disease.
Hem A and B
Known as Christmas Disease
Hemophilia B
Needed for platelet adhesion.
vWF
Can be autosomal dominant or acquired.
von Willebrand’s disease
This is prolonged in Hemophilia A and B, and von Willebrand’s.
Partial Thromboplastin Time
Test of the intrinsic pathway.
Partial Thromboplastin Time
Normal Partial Thromboplastin Time
24-38 seconds
Normal Prothrombin Time
11-17 seconds
Assesses platelet function
Bleeding time.
The time it takes to stop bleeding.
Bleeding Time
This blood disease has increased bleeding time.
von Willebrand’s.
Joint and muscle hemorrhages are common in this disease.
Hemophilia
T/F: Non-invasive endo is preferred over extractions in people with bleeding disorders.
True
Avoid prescribing these medications in someone with a bleeding disorder. Cause increased bleeding.
Aspirin or Ibuprofen
