medical statistics

Question 1

What happens in Phase 0 of a clinical trial?

Answer 1

small group of volunteers, used to assess pharmacodynamics and pharmacokinetics

Question 2

What happens in Phase 1 of a clinical trial?

Answer 2

Testing of drug on healthy volunteers to find appropriate dosing

Question 3

What happens in Phase 2 of a clinical trial?

Answer 3

Testing of drug on large group of patients to assess efficacy and safety

Question 4

What happens in Phase 3 of a clinical trial?

Answer 4

Testing of drug on a large group of patients to confirm effectiveness, safety and comparing to existing interventions

Question 5

what does it mean if confidence interval includes 1?

Answer 5

finding is not significant

Question 6

what is a cohort study

Answer 6

examining groups of people over a period of time, where one group is exposed to a certain risk factor and the other group is not in order to establish links between exposure and a health related outcome such as the development of disease.

Question 7

what is a case control study?

Answer 7

participants recruited based on the presence of an outcome from the outset of the study. suitable controls (participants without the outcome of interest) are identified and selected for the study. Data of exposure to a risk factor is recorded retrospectively for each of the participants and then compared between cases and controls.

Question 8

what is a cross sectional study?

Answer 8

collection of data from a population in a specific time point.