Medical Conditions in Pregnancy Flashcards

1
Q

gestational DM screening

A

24-28 weeks
50 mg one hour oral glucose challenge
> 130 is abnormal

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2
Q

risk factors for gestational DM

A
obesity
previous gestational DM
fam hx of DM
known glucose intolerance
advanced age
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3
Q

maternal complications of GDM

A

gestational HTN
preeclampsia
C-section delivery
DM later in life

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4
Q

fetal complications of GDM

A
macrosomia
neonatal hypoglycemia
hyperbilirubinemia
operative delivery
shoulder dystocia
birth trauma
stillbirth
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5
Q

GDM management

A

blood glucose monitoring
diabetic teaching
diet control vs medication tx
increase exercise

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6
Q

maternal evaluation for GDM

A

urine every trimester
EKG
eye exam in 1st trimester
daily glycemic monitoring

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7
Q

fetal evaluation for GDM

A

early dating US
fetal EKG
biochemical testing for congenital malformations
fetal US every 3-4 weeks starting at 28 weeks
fetal testing every week starting at 32 weeks

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8
Q

maternal hyperthyroidism

A

dx made by elevated T4 and suppressed TSH

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9
Q

tx for maternal hyperthyroidism

A

propylthiouracil in 1st trimester

methimazole in 2nd and 3rd trimester

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10
Q

fetal effects of maternal hyperthyroidism

A
fetal hypothyroidism
goiter
prematurity
growth restriction
stillbirth
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11
Q

thyroid storm triggers

A

infection
noncompliance with meds
*labor
*C-section

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12
Q

thyroid storm sx

A

hyperthermia
tachycardia
perspiration
high output cardiac failure

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13
Q

thyroid storm tx

A
beta-blockers
propylthiouracil
dexamethasone
IVFs
antipyretics
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14
Q

risks of untreated maternal hypothyroidism

A
spontaneous abortion
preeclampsia
abruption
low birth weight
stillbirth
cretinism
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15
Q

maternal hypothyroidism management

A

levothyroxine

monthly TSH and T3/T4 monitoring

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16
Q

neonatal thyrotoxicosis

A

due to transplacental transfer of thyroid-stimulating Abs

16% mortality rate

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17
Q

neonatal hypothyroidism causes

A

thyroid dysgenesis
inborn errors of thyroid function
drug-induced

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18
Q

postpartum cardiomyopathy

A

develops within the last weeks of pregnancy or within 6 months of postpartum

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19
Q

risk factors for developing postpartum cardiomyopathy

A

preeclampsia
HTN
poor nutrition

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20
Q

pregnancy with underlying cardiac dz management

A
co-management with cardiologist
avoid excess weight gain and edema
avoid strenuous activity
prevent anemia
avoid infection
anticoagulation prn
maternal and fetal EKGs
maternal ECHO
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21
Q

immune idiopathic thrombocytopenia

A

immunoglobulins attach to maternal platelets

tx:
prednisone
IVIg
platelet transfusion
splenectomy
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22
Q

SLE flare tx while pregnant

A

prednisone

23
Q

fetal complications of SLE

A

preterm delivery
fetal growth restrictions
stillbirth
miscarriage

24
Q

antiphospholipid syndrome tx during pregnancy

A

heparin and low-dose ASA

full coagulation if hx of thrombosis

25
acute renal failure management
labs - urine, creatinine, etc cardiovascular studies urologic studies
26
acute renal failure tx
pre-renal: fluid replacement renal: diuretic or hemodialysis post-renal: remove obstruction
27
is it recommended to get pregnant post-renal transplant?
nah
28
causes of asymptomatic bacteriuria
urinary stasis and glucosuria tx: abx
29
pyelonephritis risks
may cause increased uterine activity and preterm labor
30
pyelonephritis tx
IVFs abx antipyretics tocolytics prn
31
tx for nausea and vomiting of pregnancy
Vit B6 doxylamine promethazine
32
hyperemesis gravidarum
persistent N/V associated with >5% loss of pre-pregnancy weight, ketonuria, and dehydration unknown cause
33
hyperemesis gravidarum tx
OP management as tolerated may need hospitalization for IVFs, glucose, vitamins, etc. if severe - nasogastric feeding or parental nutrition
34
GERD tx
``` small meals avoid lying down after meals elevate head when sleeping antacids H2 blockers/PPIs ```
35
peptic ulcer tx
avoid caffeine, alcohol, tobacco and spicy foods antacids, H2 blockers/PPIs abx for H. pylori
36
Mendelson's syndrome
acid aspiration syndrome due to delayed gastric emptying and increased pressure
37
Mendelson's syndrome prevention
decrease acid in stomach | do not feed in labor
38
Mendelson's syndrome tx
O2 maintain airway watch for ARDS
39
intrahepatic cholestasis of pregnancy (ICP)
cholestasis and pruritis in second half of pregnancy benign course for mom increased risk of meconium and fetal demise
40
ICP tx
cold baths and bicarbonate washes ursodeoxycholic acid fetal surveillance possible early fetal delivery
41
acute fatty liver of pregnancy
hepatic failure due to an unknown cause
42
acute fatty liver of pregnancy tx
pregnancy termination | supportive care
43
anemia of pregnancy
secondary to iron deficiency hgb < 11 in 1st trimester hgb < 10.5 in 2nd and 3rd trimester
44
anemia tx
iron supplementation
45
why are pregnant women at increased risk for DVT and PE?
pregnancy is a hypercoagulable state | 5 fold increased risk for DVT
46
when are pregnant women at the greatest risk for DVT?
first 5 weeks postpartum
47
DVT tx
lovenox or heparin | no coumadin during pregnancy!!
48
most common pulmonary dz of pregnancy
asthma tx same as non-pregnant
49
which antiepileptics should absolutely not be used in pregnancy?
valproic acid, phenytoin or phenobarbital *technically all anti-epileptics are teratogenic BUT these 3 are the worst
50
risk factors for postpartum depression
personal or fam hx of depression hx of abuse drug abuse hx of personality disorder
51
depression tx during pregnancy
avoid antidepressants during 1st trimester if possible Lol I'm fucked
52
incidence of postpartum blues
70-80% | due to hormone fluctuations
53
incidence of postpartum depression
10-15%