Medical conditions in pregnancy Flashcards
Cut-off values for anaemia?
<110 early in pregnancy
<105 after 28 weeks
Management of anaemia in pregnancy?
Oral iron + 5mg folate
Management of APLS?
Low dose aspirin + LMWH from week 6-34
Which asthma drug should be avoided in pregnancy as the safety data is limited?
Leukotriene receptor antagonists
Drug which can cause severe asthma attacks if used in labour?
Syntometrine (contains ergometrine)
Adjustment of levothyroxine in pregnancy?
Usually need to increase dose (foetus not affected by maternal thyroid hormones)
Management of hyperthyroidism in pregnancy? (2)
Carbimazole
Propylthiouracil preferred post-partum if breastfeeding, as less concentrated in milk
Management of confirmed VTE in pregnancy?
LMWH for remainder of pregnancy and at least 6 weeks postpartum (minimum duration 3 months)
Oral option for VTE which is safe in breastfeeding?
Warfarin- avoid DOACs
Which drugs used in diabetes should be stopped in pregnancy?
Sulfonylureas
Insulin requirements increase by what factor in pregnancy?
2-3x
When does gestational diabetes usually develop?
2nd trimester
When should post-partum OGTT take place for gestational diabetes?
6 weeks
Management of glycosuria pregnancy?
Repeat dipstick; OGTT if remains positive
Which anti-epileptic is associated with the highest risk of congenital malformation?
Sodium valproate
Risk associated with topiramate?
Increased risk of cleft palate if taken in 1st trimester
Management of babies born to epileptic mothers?
All should receive IM vitamin K at birth (risk of haemorrhagic disease of the newborn)
Diagnosis of gestational diabetes: fasting glucose
> 5.6
Diagnosis of gestational diabetes: 2hr OGTT
> 7.8
