Medical conditions Flashcards

1
Q

Aetiology of cardiac conditions in children

A

Maternal rubella
Maternal diabetes
Maternal drugs – alcohol, phenytoin
Foetal chromosomal abnormality- Down syndrome
Foetal inborn errors of metabolism and connective tissue disorder-Williams syndrome

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2
Q

name examples of cardiac conditions (congenital heart defects)

A

tetralogy of fallot
ASD/VSD
transposition of great arteries
CoA

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3
Q

important aspects of dental treatment in cardio disease

A

OH
nice guidelines
consult cardiologist if issues
anticoagulants/antiplts

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4
Q

down’s syndrome -
clinical features
impact

A

congenital heart lesions
atlantoaxial instability
umbilical hernia/rib abscence
immunological defects - periodontal disease
increased chance of alzheimers/hypothyroidism
Acute lymphoblastic leukaemia (20x)
-social development, motor skills, memory skills, speech and language, learning disability.

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5
Q

down’s syndrome - oral manifestation

A
high palate, CLP common
small mouth - open lip posture
macroglossia - fissured tongue
hypodontia - microdontia, delayed eruption, hypoplasia
bifid uvula
increased risk of periodontal disease - white cell chemotaxis deficiency
thick, dry fissured lips
AOB, class III, posterior crossbite
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6
Q

dental management of down syndrome

A

prevention - OHI (CHD importance), fluoride use, treat under LA if poss, CHX for perio disease

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7
Q

asthma - drugs

beta2 agonists

A

bronchodilators -
salbutamol (Blue) - short acting b2 agonist, quick onset (2-3min) last4-6hr
for acute bronchial constriction - oral/inh/iv

Salmeterol (green?) - long acting b2 agonist, slow onset (1-2hr), last 12-15hr
prevent acute bronchial constriction
ALWAYS with inh steroid

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8
Q

asthma drugs - anticholinergics

A

Ipratropium (grey)
inhibit muscarinic nerve transmissionin autonomic n
reduce mucous secretion and encourage bronchodiliation

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9
Q

asthma drugs - corticosteroids

-compound prep

A
reduce inflammation of bronchilal walls
beclomethasone (brown)
budesonide (brown)
flutisocone (orange)
mometasone (pink)
-compound prep = inh steroid and long acting B2 agon
- seritide (fluticosone/salmeterol)
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10
Q

asthma treatment order

A
1. occasional b2 agonist
2 low dose inh steroid
3 high dose inh steroid
4 long acting b2 agonist/antimuscarinic
5 oral steroid
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11
Q

cystic fibrosis

who

A

1 in 2500 births. Autosomal recessive
affects EXOCRINE system - thick mucous produced and lack of pancreatic lipase - malabsorption
diabetes and liver cirrhosis
recurrent chest infections

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12
Q

oral manifestations of cystic fibrosis

dental implications

A
thickened saliva
reduced caries (high ammonia in saliva)
greater calculus levels
lower plaque and gingival disease
enamel defects and delayed eruption
-GA risk, resp failure, high sugar intake (large energy diet), diabetes and liver disease
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13
Q

chemotherapy side effects

-acute oral complications

A

bone marrow suppression - immunocompromised
anorexia
nausea and vomiting
alopecia
-gingival bleeding / halitosis / taste disturbance / dysphagia / trismus / tooth mobility / paraesthesia
-infection risk

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14
Q

what is mucocitis and how is it treated

A

oral ulceration of mucosa - painful (stomatitis to burning and ulceration)
mucocitis localised to oropharynx

treatment - sodium bicarbonate every 2hr
gelclair (2hr)
biotene mw - (2hr)
DIFFLAM (mw/spray) 2hr
lignocaine application
benzocaine flavoured gel
orabase with/out corticosteroid
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15
Q

biotene mw - how do they work

A

Moisturises oral mucosal cells
Antibacterial effect of proteins
Reinforces antibacterial activity of saliva
Contains Xylitol which inhibits bacteria
Triple enzyme formula: lysozyme;
lactoperoxidase; lactoferrin.
Contains fluoride, glucose oxidase, aloe vera

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16
Q

renal failure - oral findings

A

~~~
Excessive plaque accumulation
Gingivitis: bleeding
Gingival overgrowth
Enamel hypoplasia
Some develop periodontitis
Osseous changes
Pulp obliteration
Pallour, petechiae, ecchymosis
Uraemic stomatitis
Reduced caries

17
Q

dental considerations for renal failure

A

Bleeding tendencies and haemostasis
Treatment: day after dialysis
Infections can be poorly controlled
Signs of inflammation can be masked
Increased risk blood borne viral infections
Osseous lesions may be seen jaws; lamina dura thinning, osteolytic lesions, giant cell lesions

  • antimicrobials - give lower doses of penicillin’s (except flucloxacillin & phenoxymethyl pen), metronidazole and cephaloridine to avoid toxicity CNS
18
Q

diabetes mellitus symps/signs

-undiagnosed features

A
polyuria/polydipsia/tired/recent weight loss
weakness/fatigue/mental confusion/acetone breath
-
Vomiting, nausea, abdominal pain
Renal dysfunction
Hyperventilation – metabolic acidosis
Dehydration
Hypovolaemia
Pasasthesia(extremities)
Dysaesthesia
Gastrointestinal neuropathy
Muscle wasting
Shock
Coma
19
Q

oral manifestations of diabetes mellitus

A
Reduced salivary flow
Xerostomia
Burning mouth/tongue
Candidal infection
Altered taste
Progressive periodontitis
Dental caries
Oral neuropathies
Parotid enlargement
Sialosis
Delayed wound healing
20
Q

diabetic hypo coma features

A
Mood change, irritability
Strong bounding pulse
Nausea and stomach ache
Hunger
Shaking, tingling around mouth
Increased gastric motility
Hypothermia
•Disorientation
•blurred vision
•Lethargy
•slurred speech
•Sweaty skin
21
Q

diabetic hyper coma features

A
Weak pulse
Rapid deep breathing (Kussmaul’s respiration)
Dry skin
Acetone breath
Increased frequency of micturition (to want to urinate)
Thirst
Severe hypotension
Abdominal pain and vomiting
Loss of consciousness (diabetic coma)
22
Q

Asthma intra-oral features

A
  • acidic inhalers: wear?
  • dry mouth: caries risk
  • gastric reflux: cough/laxity of lower oesophageal sphincter
23
Q

Renal Failure/disease intra-oral features

A
  • excessive plaque accumulation
  • gingivitis/bleeding
  • gingival hyperplasia
  • enamel hypoplasia
  • pulp obliteration
  • ecchymosis/pallour
  • reduced caries
24
Q

Dental considerations for Renal failure

-when to treat

A
  • bleeding tendency/haemostasis
  • poorly controlled inf
  • > risk of BBVs
  • Inh sedation is OK but IV sedation has a risk of thrombophlebitis
  • TREAT DAY AFTER DIALYSIS
25
Renal failure & antibiotics: considerations
- NEUROTOXICITY - lower doses of penicillin - contact renal consultant
26
Renal transplant considerations | -CVS/GIT/Bone disease
LIFELONG IMMUNOSUPPRESSION! - anaema/platelet dysfunction - GIT: gastritis/peptic ulcer - CVS: hypertension/atherosclerosis/MI/heart failure - bone: low calcium/elevated PTH/high phospurus
27
what can corticosteroids cause in Renal failure patients
-SCLEROTIC PULP CANALS
28
Causes of Chronic Renal Disease
Glomerulonephritis (25 % of cases). *Diabetes mellitus. *Severe pyelonephritis. *Hypertension *Polycystic kidney disease. *Drugs, nonsteroidal anti-inflammatory drugs (NSAIDs). *Connective tissue diseases such as systemic lupus erythematosus and polyarteritis nodosa. *Renal stones
29
What oral conditions are commonly found in those having gone through Dialysis
bone lesions, xerostomia, unpleasant taste, delayed tooth eruption, enamel hypoplasia, foul odor, oral hairy leukoplakia, uremic stomatitis, oral malignancy, gingival hypertrophy and calcifications leading to obliteration of the pulp chamber and canals
30
Specific oral manifestations of kidney disease
- Amelogenesis Imperfecta (Enamel-renal syndrome is a term used to describe amelogenesis imperfecta with nephrocalcinosis. This is a rare syndrome and certain cases of it can lead to renal insufficiency) - Pallor of the Oral Mucosa - Periodontal disease - Xerostomia - Candidiasis - Brown's tumour (parathyroidism-end stage) -gingival hyperplasia - hairy leukoplakia - Neoplasm - kaposi's sarcoma
31
Common findings in paediatric patients with kidney disease
Brown teeth delayed eruption tooth structure abnormalities
32
Low caries is often reported in children with chronic kidney disease...why?
Low caries risk is reported in pediatric patients with renal disease because of the highly buffered and alkaline saliva that results from elevated phosphate and urea concentrations
33
Name some treatment considerations for patients with Chronic Kidney disease
BLEEDING RISK INFECTION RISK Drug interactions: ABx contraindications with nephrotoxicity