MedChem3 Elz Flashcards by Michaela Stadler

Q

Freisetzung von AA

A

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Q

Lipoxygenaseweg

Leukotriene

A

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Q

Lipoxine, Lipoxygenaseweg

A

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Q

Thromboxan, Prostacyclin

aus PG H2

A

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Q

Prostanoide aus PG H2 (außer TX,PG I)

A

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Q

Cyclooxygenaseweg bis PG H2

A

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Q

Salicylsäure-Entstehung

A

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Q

ASS-Synthese

A

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Q

ASS Metabolismus

A

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Q

Diclofenac Metabolismus

A

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Q

3 Diclofenac Synthesen

A

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Q

Fenbufen Metabolismus

A

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Q

Nabumeton

A

Prodrug

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Q

Indometacin Metabolismus

A

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Q

Indometacin Synthese nach Merck

A

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Q

Indometacinsynthese nach Sumitomo

A

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Q

Synthese von racemischem Ketoprofen

A

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Q

Industrielle Herstellung von S-Naproxen

A

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Q

Stereoselektive Synthese von S-Naproxen

A

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Q

Ibuprofen-Inversion

A

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Q

Ibuprofen Metabolismus

A

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Q

Sepracor-Prozess Ibuprofen

A

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Q

Piroxicam Resonanzstabilisierung

A

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Q

Piroxicam Metabolisierung

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Lornoxicam Metabolismus und Synthese

Pyrazolidindion -Resonanzstabilisierung im schwachsauren

Metabolisierung von Phenylbutazon

Phenazon Metabolisierung

Phenazon, Metamizol Synthese

Paracetamol Schädigung und endogene/exogene Entgiftung

Synthese von Paracetamol

Synthese von Paracetamol nach Hoechst-Celanese

Acetylierungen zu Paracetamol (4)

COX-2 Hemmer Generationen mit Beispielen

Strukturbeispiele Cox-2 Inhibitoren

Celecoxib Synthese

Parecoxib Metabolismus

Opioid-Rezeptoren

Wirkung am Opioid-Rezeptor und Agonisten

Morphinwirkung peripher

Morphinwirkung Zentral

Säure-Base-Eigenschaften von Morphin

Opium Definition

Die wichtigsten Opiumalkaloide

Morphin Stereochemie

Morphin Synthese

Partialsynthetische Morphinderivate

Partialsynthetische Codein und Thebainderivate

Buprenorphin und Etorphin Metabolismus

Vereinfachung des Morphin Skeletts

Pentazocin Synthese

Opioidrezeptor-Antagonisten Strukturwirkungsbeziehung

Pethidin-Synthese

Tramadol Synthese

Tilidin Synthese

Levomethadon Synthese

Methadon Metabolismus

Fentanyl Synthese

Meptazinol Synthese

Therapie der Heroinabhängigkeit

Antidiarrhoica Opioide Diphenoxylat-Metabolismus Loperamid Synthese

Marquis-Reaktion

Umlagerung zu Aopmorphin

Zimmermann Reaktion

Potentielle Analgetika mit anderen WM

Cannabinoid-Rezeptor-Agonisten

Stoffe mit Wirkung auf die Atemwege

Antitussiva (opioid, nichtopioid)

Mukolytika, Ambroxol Synthese

Mukolytika, ACC Synthese und Wirkung

Formel der COX-1/COX-2 Selektivität

Aufgabe 1

Aufgabe 2