MedChem3 Elz Flashcards

1
Q

Freisetzung von AA

A
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2
Q

Lipoxygenaseweg

Leukotriene

A
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3
Q

Lipoxine, Lipoxygenaseweg

A
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4
Q

Thromboxan, Prostacyclin

aus PG H2

A
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5
Q

Prostanoide aus PG H2 (außer TX,PG I)

A
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6
Q

Cyclooxygenaseweg bis PG H2

A
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7
Q

Salicylsäure-Entstehung

A
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8
Q

ASS-Synthese

A
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9
Q

ASS Metabolismus

A
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10
Q

Diclofenac Metabolismus

A
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11
Q

3 Diclofenac Synthesen

A
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12
Q

Fenbufen Metabolismus

A
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13
Q

Nabumeton

A

Prodrug

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14
Q

Indometacin Metabolismus

A
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15
Q

Indometacin Synthese nach Merck

A
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16
Q

Indometacinsynthese nach Sumitomo

A
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17
Q

Synthese von racemischem Ketoprofen

A
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18
Q

Industrielle Herstellung von S-Naproxen

A
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19
Q

Stereoselektive Synthese von S-Naproxen

A
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20
Q

Ibuprofen-Inversion

A
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21
Q

Ibuprofen Metabolismus

A
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22
Q

Sepracor-Prozess Ibuprofen

A
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23
Q

Piroxicam Resonanzstabilisierung

A
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24
Q

Piroxicam Metabolisierung

A
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25
Q

Lornoxicam Metabolismus und Synthese

A
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26
Q

Pyrazolidindion -Resonanzstabilisierung im schwachsauren

A
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27
Q

Metabolisierung von Phenylbutazon

A
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28
Q

Phenazon Metabolisierung

A
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29
Q

Phenazon, Metamizol Synthese

A
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30
Q

Paracetamol Schädigung und endogene/exogene Entgiftung

A
31
Q

Synthese von Paracetamol

A
32
Q

Synthese von Paracetamol nach Hoechst-Celanese

A
33
Q

Acetylierungen zu Paracetamol (4)

A
34
Q

COX-2 Hemmer Generationen mit Beispielen

A
35
Q

Strukturbeispiele Cox-2 Inhibitoren

A
36
Q

Celecoxib Synthese

A
37
Q

Parecoxib Metabolismus

A
38
Q

Opioid-Rezeptoren

A
39
Q

Wirkung am Opioid-Rezeptor und Agonisten

A
40
Q

Morphinwirkung peripher

A
41
Q

Morphinwirkung Zentral

A
42
Q

Säure-Base-Eigenschaften von Morphin

A
43
Q

Opium Definition

A
44
Q

Die wichtigsten Opiumalkaloide

A
45
Q

Morphin Stereochemie

A
46
Q

Morphin Synthese

A
47
Q

Partialsynthetische Morphinderivate

A
48
Q

Partialsynthetische Codein und Thebainderivate

A
49
Q

Buprenorphin und Etorphin Metabolismus

A
50
Q

Vereinfachung des Morphin Skeletts

A
51
Q

Pentazocin Synthese

A
52
Q

Opioidrezeptor-Antagonisten Strukturwirkungsbeziehung

A
53
Q

Pethidin-Synthese

A
54
Q

Tramadol Synthese

A
55
Q

Tilidin Synthese

A
56
Q

Levomethadon Synthese

A
57
Q

Methadon Metabolismus

A
58
Q

Fentanyl Synthese

A
59
Q

Meptazinol Synthese

A
60
Q

Therapie der Heroinabhängigkeit

A
61
Q

Antidiarrhoica Opioide

Diphenoxylat-Metabolismus

Loperamid Synthese

A
62
Q

Marquis-Reaktion

A
63
Q

Umlagerung zu Aopmorphin

A
64
Q

Zimmermann Reaktion

A
65
Q

Potentielle Analgetika mit anderen WM

A
66
Q

Cannabinoid-Rezeptor-Agonisten

A
67
Q

Stoffe mit Wirkung auf die Atemwege

A
68
Q

Antitussiva (opioid, nichtopioid)

A
69
Q

Mukolytika, Ambroxol Synthese

A
70
Q

Mukolytika, ACC Synthese und Wirkung

A
71
Q

Formel der COX-1/COX-2 Selektivität

A
72
Q

Aufgabe 1

A
73
Q

Aufgabe 2

A