MedChem3 Buschauer Flashcards

1
Q

Lipidsenker

Wirkstoffklassen

A
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2
Q

Artherosklerose, Arteriosklerose

A
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3
Q

HMG-CoA-Reduktase-Reaktion

A
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4
Q

Statine

Lovastatin

warum wird Enzym gehemmt

A
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5
Q

Reaktion von Pravastation im Magen

A
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6
Q

CSE-Wechselwirkungen

A
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7
Q

Fluvastatin Synthese

A
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8
Q

Fibrate

Beispiele und Wirkung

A
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9
Q

Nicotinsäure

WM

Kombi mit… und WM

A
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10
Q

Gallensäurebindende Harze

A
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11
Q

Ezetimib und Orlistat Wirkung

A
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12
Q

Arzneistoffe mit Wirkung am Histamin Rezeptor

Histamin-Struktur

Cetirizin

A
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13
Q

Histidin-Decarboxylase-Inhibitor

A
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14
Q

Chlorphenamin

A
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15
Q

Cetirizinsynthese

A
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16
Q

Loratadin

Mizolastin

Levocabastin

Azelastin

A
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17
Q

Chlorphenaminsynthese

A
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18
Q

Indikationen für H1-Antihistaminika

A
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19
Q

Terfenadin Metabolismus

A
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20
Q

H2-Antagonisten

A
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21
Q

Cimetidin-Metabolismus

A
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22
Q

Ranitidin-Synthese

A
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23
Q

Anticholinergika zum Magenschutz

WS-Beispiel

A
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24
Q

Protonenpumpenhemmer

Wirkmechanismus

Esompeprazol

A
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25
Q

Pantoprazol

A
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26
Q

Wirkmechanismus genau

Protonenpumpenhemmer

A
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27
Q

Antacida

Beispiel

A
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28
Q

Prostaglandin-Analoga als Zytoprotektiva

Magenschutz

A
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29
Q

Zytoprotektiva Sucralfat

A
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30
Q

Bisacodyl

A
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31
Q

Lactulose

A
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32
Q

Serotonin

Funktionen in der Peripherie

A
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33
Q

Selektive 5HT-Rezeptorliganden

A
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34
Q

Migränemittel

Wirkmechanismus

Sumatriptan

Elatriptan

Fovatriptan

A
35
Q

Sumatriptansynthese 1

A
36
Q

Sumatriptan-Synthese 2

A
37
Q

Telgacepant

A
38
Q

Aprepitant

A
39
Q

Ondansetron-Synthese

A
40
Q

Tropisetron

Dolasetron

Granisetron

Palonosetron

A
41
Q

Gastroprokinetika

Cisaprid

Metoclopramid

NIH Shift

A
42
Q

Diuretika, Hauptindikation

Wirkung

A
43
Q

Angriffsorte der Diuretika

A
44
Q

Na/K-ATPase

A
45
Q

Carboanhydrase-Hemmer

A
46
Q

Thiazide

Benzothiadiazin-Typ

A
47
Q

Hydrochlorothiazid Farbreaktionen

A
48
Q

Thiazide und Analoga

Butizid

Mefrusid, Chlortalidon

A
49
Q

Carbonyl-Typ

A
50
Q

Furosemid Synthese

Azosemid

A
51
Q

Reaktionsverhalten von Furosemid im Sauren

A
52
Q

Torasemid-Synthese

A
53
Q

Reaktion von Ethacrynsäure mit Glutathion

A
54
Q

Kaliumsparende Diuretika

A
55
Q

Synthese der Lacton-Partialstruktur in Pos. 17 des Steroidgerüsts

A
56
Q

Amilorid, Triamteren, Metabolismus, Kombi?

Xipamid-Metabolismus

A
57
Q

Vasopressin und seine Antagonisten

A
58
Q

Chlorthalidon-Synthesen (3)

A
59
Q

Hydrolyse von Chlortalidon

Reaktion im Sauren und Basischen

A
60
Q

Mechanismen der positiv- inotropen Stimulation

A
61
Q

Aglyka der Herzwirksamen Glykoside

A
62
Q

Targetklasse von Herzwirksamen Glykosiden

A
63
Q

Herzglykoside: Einteilung

A
64
Q

Zuckerbausteine in Herzwirksame Glykoside

A
65
Q

Digitoxin Analytik

Kedde-Reaktion

A
66
Q

Wirkdauer von Herzwirksamen Glykosiden

A
67
Q

Digoxin und Partialsynthetische Derivate

A
68
Q

Wirkung der Herzglykoside

A
69
Q

Die Rolle von GPCR-Kinasen (GKRs) bei Herzinsuffizienz

A
70
Q

cyclo-Adenosinmonophosphat

A
71
Q

PDE-III-Hemmer

A
72
Q

Antiarrhythmika Klassen

A
73
Q

Störungen der Erregungsbildung des Herzens

A
74
Q

Eingesetzte Stoffklassen bei Arrhythmien

A
75
Q

Wirkweise von Antiarrhythmika

A
76
Q

Chinidin

Identität, Reinheit, Gehalt

A
77
Q

Chinin zu Chinidin

A
78
Q

Procainamid

A
79
Q

Synthese von Disopyramid

A
80
Q

Ajmalin Prajmalin

A
81
Q

Lidocain, Tocainid, Mexiletin

A
82
Q

Metabolisierung von Lidocain

A
83
Q

Propranolol

A
84
Q

Klasse III-Antiarrhythmika

A