Med Sheet: Diabetes Meds Flashcards
1
Q
Metformin Trade Name
A
Glucophage
2
Q
Metformin Category
A
Biguanide
3
Q
Metformin Use
A
DM 2
4
Q
Metformin Usual Dose
A
500 mg bid initially
then 1000 mg bid or 850 bid/tid
max 2500 mg/day
5
Q
Metformin CIs
A
- chronic kidney dz (men SCr > 1.5, women > 1.4)
- acidosis
- hypoxia
- dehydration
- IV contrast
6
Q
Metformin AEs
A
- GI side effects most common (abd discomfort, diarrhea)
- lactic acidosis (rare)
- B12 deficiency
7
Q
Insulin Trade Name
A
Humulin R
Novolin R
8
Q
Insulin Category
A
Insulin
9
Q
Insulin Use
A
DM 1 and 2
10
Q
Insulin Usual Dose
A
- DM 1: 0.5-0.6 U/kg/day initially then 0.5-1 U/kg/day divided
- DM 2: 0.1-0.2 U/kg/day
11
Q
Insulin CIs
A
.
12
Q
Insulin AEs
A
- hypoglycemia
- weight gain
- mitogenic effects
- injection site reaction
- atrophy or hypertrophy of subQ fat tissue at injection site
13
Q
Glipizide Trade Name
A
Glucotrol
14
Q
Glipizide Category
A
Sulfonylurea
15
Q
Glipizide Use
A
DM 2
16
Q
Glipizide Usual Dose
A
2.5-5 mg qday initially
then 5-20 mg qday, max 40 mg qday
17
Q
Glipizide CIs
A
.
18
Q
Glipizide AEs
A
- hypoglycemia
- weight gain
- blunts myocardial ischemic conditioning
- low durability
19
Q
Exenatide Trade Name
A
Byetta
20
Q
Exenatide Category
A
GLP-1 receptor agonist
21
Q
Exenatide Use
A
DM 2
22
Q
Exenatide Usual Dose
A
.
23
Q
Exenatide CIs
A
.
24
Q
Exenatide AEs
A
.
25
Pioglitazone Trade Name
Actos
26
Pioglitazone Category
Thiazolidinedione (TZD)
27
Pioglitazone Use
DM 2
28
Pioglitazone CIs
.
29
Pioglitazone AEs
- weight gain
- edema
- cause or worsen heart failure
- bone fractures
- bladder cancer risk
30
Sitagliptin Trade Name
Januvia
31
Sitagliptin Category
DDP-4 inhibitor
32
Sitagliptin Use
DM 2
33
Sitagliptin CIs
.
34
Sitagliptin AEs
- urticaria
- angioedema
- pancreatitis
