Med hypocholestérolémiant Flashcards

1
Q

Citer des Med hypocholestérolémiants:

A

. l’ézétimibe

. le cholestyramide

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2
Q

L’ézétimibe: mode d’action

A

. un hypocholestérolémiant agissant par inhibition du transporteur intestinal du cholestérol.

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3
Q

L’ézétimibe: citer les effets secondaires

A

. Troubles digestifs -> douleurs abdominales, flatulences, diarrhées

. Asthénie

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4
Q

Cholestyramine: mode d’action

A

. cholestyramine se lie aux acides biliaires, ce qui inhibe le cycle entéro hépatique = élimination fécale du LDLc

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5
Q

Cholestyramine: indications

A

. hypercholestérolémie

. prurit des cholestases

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6
Q

Cholestyramine: effets

A

. Baisse LDL,

. hausse HDL,

. mais hausse des triglycérides !

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7
Q

Cholestyramide: effets secondaires

A

. constipation

. hypertriglycéridémie

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8
Q

Cholestyramide: C-I

A

. Insuffisance hépatocellulaire

. Obstruction complète des voies biliaires

. Constipation chronique

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