Mechanisms of neuroinflammation

Question 1

What is the main factor the contributes to enhanced neuroinflammation?

Answer 1

Ageing

Question 2

What other factors cause neuroinflammation?

Answer 2

• environmental- relates to gut brain axis (pathogens)
• Genetic (familial) or sporadic origin causing protein misfolding

Question 3

Name the vascular components of neuroinflammation

Answer 3

• stroke
• aneurisms = damage to blood vessels
• transient ischemic attack

= all induce neuroinflammation in the brain

Question 4

What are small vessel diseases caused by?

Answer 4

• hypertension
• atherosclerosis
• diabetes

All conditions contribute to neuroinflammation