Mechanisms of Drug Resistance in Bacteria

Question 1

Antibiotic altering enzymes

Answer 1

Bacteria uses enzymes to alter the structures of the drug

Question 2

Antibiotic degrading enzymes

Answer 2

Bacteria cleaves the drug so that it is no longer active

Question 3

Efflux mechanism

Answer 3

Microorganism pumps the antibiotic out of the cell soon after the drug has entered the cell
-ATP pumps the drug back out

Question 4

Decreased Permeability to a Drug

Answer 4

Microorganism prevents entrance of the drug into the cell

Question 5

Mechanisms of Drug Resistance in Bacteria (5)

Answer 5

1. Drug inactivation
2. Decreased membrane permeability
3. Efflux
4. Alter target
5. Change in metabolic pathways