Controlling Microbial Growth in the Body

Question 1

Antimicrobial Chemotherapy

Answer 1

Administration of chemotherapeutic drugs to control or relieve infections

Question 2

Chemotherapeutic Agents(Drugs)

Answer 2

Chemical agents that destroy pathogenic microorganisms/inhibit their growth
-Chemical used for treatment or prevention of infection

Question 3

Antibiotics

Answer 3

• Work on bacteria only
• Natural antibiotic
• Bacteria and Fungi make antibiotics

Question 4

Synthetic Drugs

Answer 4

Laboratory-derived compounds with antimicrobial effect

Question 5

Semi-synthetic Drugs

Answer 5

Antibiotics that have been altered in the laboratory

Question 6

Selective toxicity

Answer 6

Ability to kill or inhibit microbial pathogens while doing little damage to host

Question 7

Narrow spectrum drugs

Answer 7

Effective only against a limited number of pathogens (specific)

Question 8

Broad spectrum drugs

Answer 8

Attack many different kinds of pathogens (variety)

Question 9

MIC

Answer 9

Minimum inhibitory concentration

Question 10

Minimum inhibitory concentration

Answer 10

The lowest concentration of a drug that prevents growth of a microorganism

Question 11

Antibiotics Function (4)

Answer 11

1. Inhibit cell wall synthesis
2. Inhibit nucleic acid synthesis
3. Target metabolic pathways
4. Inhibit protein synthesis

Question 12

Drug resistance

Answer 12

Adaptation of microorganisms to the presence of chemotherapeutic drugs

Question 13

Drug resistance caused by (3)

Answer 13

1. Random chromosomal mutations
2. Transfer of DNA w/ resistance genes
3. Via plasmids called resistance (R) factors