mechanisms of contractions Flashcards
A skeletal muscle fiber remains at rest until
stimulated by a motor neuron
Neuromuscular junction
motor neurons connect to the sarcolemma at the motor endplate
Neuromuscular junction is a synapse where
neurotransmitter molecules transmit signals
Acetylcholine
the neurotransmitter released into the synaptic cleft that diffuses across the gap, stimulates the receptors, and initiates an impulse in the sarcolemma
Nerve impulse travels over the sarcolemma and inward along the T tubules, which triggers
the release of calcium ions (Ca++)(SR)
- Ca++ binds to troponin, which causes tropomyosin to
shift and expose active sites on actin
ACh=
Acetylcholine
Hydrolysis of adenosine triphosphate (ATP) yields the energy required for
muscular contraction
ATP binds to the myosin head and transfers its energy there to perform the work of
pulling the thin filament during contraction
Muscle fibers continually resynthesized ATP from the
breakdown of creatine phosphate
Catabolism by muscle fibers requires
glucose and oxygen (O2)
At rest, excess O2 in the sarcoplasm is
bound to myoglobin
Red fibers(slow)
muscle fibers with high levels of myoglobin (used for long term work like running miles)
White fibers (fast)
muscle fibers with little myoglobin (short and fast term like 200m dash)