Mechanisms/Drug Class Flashcards
What is the mechanism of action of hormone replacement therapy?
Decrease bone resorption by osteoclasts
estrogen + progestin
hormone replacement therapy
What is the mechanism of action of selective receptor modulators (SERMs)?
Estrogen receptor agonist in bone, estrogen antagonist in endometrium and breast
raloxifene
SERM
What is the mechanism of action of bisphosphonates?
Decrease bone resorption by osteoclasts
alendronate
bisphosphonate
risedronate
bisphosphonate
ibandronate
bisphosphonate
pamidronate
bisphosphonate
zoledronate
bisphosphonate
What is the mechanism of action of RANKL antagonists?
Decrease bone resorption by osteoclasts
denosumab
RANKL antagonist
What is the mechanism of action of calcitonin?
Decrease bone resorption by osteoclasts
salmon calcitonin
calcitonin
What is the mechanism of action of bone anabolic agents?
Increase bone formation by osteoblasts