Mechanisms Bacterial Pathogenicity Flashcards
1
Q
What are the key events in bacterial pathogenesis?
A
1) Colonisation
2) multiplication
3) transmission
2
Q
What may colonisation involve?
A
Stable adhesion to epithelial surface
Invasion into host cells
3
Q
What are 2 mechanisms of invasion?
A
1) Zipper mech
2) Trigger mech
4
Q
What does the zipper mechanism involve?
A
Receptor mediated endocytosis
5
Q
How do Shigella, Listeria, Rickettsia spread through epithelial cells?
A
Escape from entry vacuole into cytosol
