Mechanisms Flashcards
Sulphonamides
Folic acid inhibitor
static
Trimethoprim
folic acid inhibitor
static
broad
gram +/-
Penicillin
B-lactam
Cidal
very broad
gram+/-
Cephalosporins
modified B-lactam
cidal
broad
Gram+/-
Monobactam
Mod B-lactam
cidal
Gram -
Carbapenems
mod B-lactam
cidal
broad
gram +/- anerobes
Tetracyclines
t-RNA inhibitor
static
broad
Aminoglycosides
inhibit cell wall synthasis
cidal
broad
only some gram -
Glycopeptides
inhibit cell wall synthasis
cidal
Gram +
Macrolides
Inhibit translocation of protiens
cidal/static
broad
not against some gram-
Fusidic acid
inhibit protein synthasis
gran +
Quinolones
inhibit DNA transcription
cidal
broad (most)
Metronidazole
Inhinits synthasis and breaks down DNA
cidal
gram + anaerobes
not effective against aerobic bacteria
Nitrofurantoin
Disrupts DNA
cidal
Gram +
Tetra-cyclines
Inhibit protein synthasis
static
broad