Mechanism Of Action

Question 1

MOA Adenosine

Answer 1

Decrease tachycardias that originate above the ventricles ( in SA and VA nodes)

Question 2

MOA Amiodarone

Answer 2

•Blocks multiple channels: sodium, potassium, calcium
•Blocks alpha and beta-adrenergic receptors
•Prolongs effective refractory period
•Slows conduction through HIS-purkinje system and • accessory pathways

Question 3

MOA Atropine

Answer 3

•blocks acetylcholine receptors
•decrease GI secretion
•dilate bronchioles and decrease respiratory tract secretions
•decrease vagal tone resulting in increased heart rate and AV conduction

Question 4

MOA Diltiazem

Answer 4

Open calcium channels preventing repolarization until dissociation

Decrease SA node discharge, VA node conduction, after load, and myocardial contractility

Question 5

MOA Dopamine

Answer 5

•alpha and beta Adrenergic receptor stimulator
•dopaminergic receptor stimulator
•precursor of norepinephrine
-low dose: 1-2mcg/kg/min (Renal Dose)
-moderate dose: 2-10mcg/kg/min(Cardiac Dose)
-high dose: 10-20mcg/kg/min(Vasopressor dose )

Question 6

MOA lidocaine

Answer 6

Increase V-fib threshold

Acts only on ventricular rhythms

Blocks fast sodium channels increasing recovery period during repolarization

Suppresses ventricular dysthymias by stabilizing cell membranes

Question 7

MOA metoprolol

Answer 7

Reduce cardiac output as well as O2 demand abd inhibits bronchodilation

Question 8

MOA Verapamil

Answer 8

Dilate coronary arteries

Open calcium channels preventing re polarization until dissociation

Decrease SA nose discharge, AV nose conduction, afterload, and myocardial contractility

Question 9

MOA Epinephrine

Answer 9

Cause fight or flight