mechanis Flashcards
how do u make a ketal
from a ketone and a alcohol
hew do u make a hemi ketal
from a ketone and alcohol next it continues to make a ketal
how do u make hemi acetal
from a aldehyde and an alchol next ot makes acetal
how do u make acetal
aldehyde and alcohol
reaction with aldehyde and ketone with water makes
a hydrate but first goes through a transition state
whan does sn2 reactions happen
very good nucleophile and primary and 3 sunstance 1 transition state
inversionof steriochem
wnhen does sn1 happen
weak and large nu
3
very good leaving group
stabilized carbocation- make it planar
makes a racemic mixture
what happens to the alpha carbon next to a carbonyl
the protons are very acidic and base attachs it normally to create an enolate
how do u make an ester
acyl chloride and alcohol
carboxylic acid and alcohol- catalyst
how to make an amide
acyl chloride and amine
cant do it with carboxylic acid and amine as kit will make a salt due due to acid and base make a salt
how does nature make amide bonds from carboxylic acid
thioester, actyl coa thioester, acyl phosphate
hydrolysis of an ester
produces carboxylic acid and an alcohol- in acid
with a base it produces a carboxylate and and alcohol due to the nucleophile be more nucleophilic
hydrolysis of an amide
in acid the carbonyl need to be protonated by an acid so that the amide is no longer basic and the electrons become localized- it produces a carboxylic acid and an NH3 then to an ammonium due to the acid
with a base the it produce amine with a carboxylic acid but as its in basic condition it becomes a carboxylate