mechanis Flashcards

1
Q

how do u make a ketal

A

from a ketone and a alcohol

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2
Q

hew do u make a hemi ketal

A

from a ketone and alcohol next it continues to make a ketal

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3
Q

how do u make hemi acetal

A

from a aldehyde and an alchol next ot makes acetal

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4
Q

how do u make acetal

A

aldehyde and alcohol

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5
Q

reaction with aldehyde and ketone with water makes

A

a hydrate but first goes through a transition state

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6
Q

whan does sn2 reactions happen

A

very good nucleophile and primary and 3 sunstance 1 transition state
inversionof steriochem

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7
Q

wnhen does sn1 happen

A

weak and large nu
3
very good leaving group
stabilized carbocation- make it planar
makes a racemic mixture

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8
Q

what happens to the alpha carbon next to a carbonyl

A

the protons are very acidic and base attachs it normally to create an enolate

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9
Q

how do u make an ester

A

acyl chloride and alcohol
carboxylic acid and alcohol- catalyst

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10
Q

how to make an amide

A

acyl chloride and amine
cant do it with carboxylic acid and amine as kit will make a salt due due to acid and base make a salt

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11
Q

how does nature make amide bonds from carboxylic acid

A

thioester, actyl coa thioester, acyl phosphate

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12
Q

hydrolysis of an ester

A

produces carboxylic acid and an alcohol- in acid
with a base it produces a carboxylate and and alcohol due to the nucleophile be more nucleophilic

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13
Q

hydrolysis of an amide

A

in acid the carbonyl need to be protonated by an acid so that the amide is no longer basic and the electrons become localized- it produces a carboxylic acid and an NH3 then to an ammonium due to the acid

with a base the it produce amine with a carboxylic acid but as its in basic condition it becomes a carboxylate

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