Mechanical Ventilation Flashcards
What are some clinical objectives of mechanical ventilation?
Reverse hypoxemia, resp acidosis, prevent / reverse atelectasis, allow for sedation with NMBAs, decrease ICP by controlling pCO2, decrease myocardial and systemic O2 demand
What is normal pCO2?
35-45 mmHg
What is normal paO2?
80-100 mmHg
What is normal blood pH?
7.35 - 7.45
Why does tachypnea cause respiratory alkalosis? What is impact on brain?
Too much CO2 being blown off, cerebral vessels constrict if < 35 pCO2, therefore resp alkalosis causes worsened cerebral perfusion
What are the types of mechanical ventilation?
1) Negative pressure –> Iron lung, vacuum pressure draws back the chest wall to allow passive inspiration
2) Positive pressure –> Mechanical drive mechanism to force gas into lungs
3) ECMO –> Blood is run through an oxygenator then returned to the pt
How do positive pressure ventilators maintain a closed system?
Filter and artificial humidifier cleans and warms/humidifies gas as it exits medic air port before it reaches the inspiratory port. Gas is exhaled into the filter before released into the atmosphere
How does a long term humidifier work and what are the cons?
Humidifier is built into the vent circuit to warm/humidify gas before entering the inspiratory port.
Frequent disconnection of circuit required to clean it / change it / empty water buildup which can cause VAP for pts and aerosolization for caregivers
How does a short term humidifier work and what are the cons?
HME filter attached to y junction at the inspiratory and expiratory ports. Traps heat and warmth from pt’s own body during exhalation and uses it to humidify inspirations.
Secretions buildup can block the filter and cause VAP / frequent changes. Therefore not used for chronic vents with lots of secretions.
What are the 4 types of positive pressure ventilators?
1) Volume cycled
2) Pressure cycled
3) Flow cycled
4) Time cycled
What is volume cycled ventilation and which pts can get it?
Volume is guaranteed, pressure changes depending on lung compliance (Peak airway pressure fluctuates)
Pressure can be too high causing barotrauma
Used on pts with compliant lungs
What is pressure cycled ventilation and which pts can get it?
Pre-set pressure, volume (Vt) fluctuates as once pressure is reached the machine stops flow of gas
Safer for pts with non-compliant lungs
Number of breaths can be increased to make up for lost Vt (pressure and time can be cycled together)
What is flow cycled ventilation?
Inspiration ends at preset flow rate (less commonly used)
What is time cycled ventilation?
Preset time interval for inspiration (set resp rate)
What is lung compliance? What is the normal?
How easily lung can accept a volume of gas, is relationship between pressure (Paw) and volume (Vt)
Normal compliance is 15 - 25cm H20
Increased pressures indicate deterioration, > 45 risks barotrauma
What factors can decrease lung compliance?
1) Stiffening of lungs (pneumonia, fibrosis)
2) Chest wall distensibility (abdominal pressure)
3) Conditions occupying intrathoracic space (pneumothorax, pleural effusion)
What is the ideal tidal volume for a person?
6-8ml / kg of body weight
What are ideal standards for FiO2 for a vented pt?
Maintain PO2 > 60, SaO2 > 90, FiO2 < 0.6 to avoid oxygen toxicity
How is minute volume calculated?
MV = f x Vt
If MV is too large, need to decrease f to avoid blowing off CO2
What is the normal inspiration : expiration ratio?
1 : 2 spontaneously
What is PEEP, pros, and what is normal physiologic PEEP?
Pressure left in lungs at the end of expiration, allows for alveoli to stay open and prevent collapse, increase SA for ventilation, allows PO2 to be maintained at less FiO2
Physiologic = 2.5 cm H20
What is alveolar recruitment strategy?
High level of PEEP for about 20 secs to recruit collapsed alveoli short term