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Final Farmaco > Mecanismos de acción ATB > Flashcards

Mecanismos de acción ATB Flashcards

1
Q

Betalactamicos

A

Unión a las PBPs, inhibición de la sínntesis de peptidoglucanos; Inhiben la mureína sintetasa

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2
Q

Glucopeptidos

A

Inhiben transglucolasas

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3
Q

Bacitracina

A

Inhibe el transporte del nucleótido Park

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4
Q

Polimixinas

A

Alteran la permeabilidad de la membrana

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5
Q

Fosfomicina

A

Se une a la enzima piruviltransferasa

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6
Q

Aminoglucosidos

A

Unión IRREVERSIBLE a subunidad 30s

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7
Q

Tetraciclinas

A

Unión REVERSIBLE a subunidad 30s

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8
Q

Macrolidos

A

Unión reversible a la subunidad 50s (inhibe traslocación) (sitio cercano a lincosamidas y fenicoles)

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9
Q

Lincosamidas

A

Unión a la subunidad 50s (sitio cercano a lincosamidas y fenicoles)

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10
Q

Fenicoles

A

Unión a la subunidad 50s (inhibe transpeptidación) (sitio cercano a lincosamidas y fenicoles)

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11
Q

Pleuromutilinas

A

Idem macrolidos y lincosamidas

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12
Q

Aminociclitoles

A

Inhiben subunidad 30s

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13
Q

Sulfonamidas

A

Compiten por el PABA en la síntesis de AN

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14
Q

Fluoroquinolonas

A

Inhiben la ADN girasa y topoisomerasa IV bacterianas

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15
Q

Rifamicinas

A

Inhiben la ARN polimerasa ADN dependiente

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16
Q

Nitrofuranos y Nitroimidazoles

A

Son reducidos por la enzima nitrorreductasa produciendo metabolitos reactivos

Final Farmaco (5 decks)

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