Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Psychiatry pro +1700 > MDD and bipolar II > Flashcards

MDD and bipolar II Flashcards

1
Q

What is the role of psychotherapy and psychopharmacology?

A

Complementary–psychopharmacology outcomes are largely improved with psychotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is transcranial magnetic stimulation?

A

A noninvasive method used to stimulate small regions of the brain. During a TMS procedure, a magnetic field generator, or “coil”, is placed near the head of the person receiving the treatment. The coil produces small electric currents in the region of the brain just under the coil via electromagnetic induction. The coil is connected to a pulse generator, or stimulator, that delivers electric current to the coil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the role of ketamine in the treatment for depression? What is the MOA?

A

Rapid response

NMDA receptor antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the role of exercise in MDD?

A

Treatment, but not cure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the black box warning for antidepressants?

A

Increase risk for suicidal ideation if young. Usually occurs in the first 2 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

True or false: improvements in mood can be seen in the first week of antidepressant therapy

A

True, but smaller than full effect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the MOA of duloxetine?

A

SNRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the difference in response vs remission in the treatment of MDD?

A
  • Response = 50% reduction

- Remission = 100%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Should you dose antidepressants according to severity of symptoms?

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the major TCAs?

A

Imipramine

Amitriptyline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the MOA of venlafaxine?

A

SNRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the MOA of desvenlafaxine?

A

SNRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the MOA of levomilnacipran?

A

SNRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the MOA of fluoxetine?

A

SSRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the MOA of fluvoxamine?

A

SSRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the MOA of paroxetine?

A

SSRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the MOA of sertraline?

A

SSRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Which of the SSRIs can cause QTc prolongation?

A

Citalopram and escitalopram

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the MOA of SNRIs?

A

Increase 5HT and NE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

True or false: there is no such thing as a stronger or weaker antidepressant

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is the MOA of vilazodone?

A

SSRI with 5HT1 binding properties

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is the MOA of vortioxetine?

A

SSRI with multiple serotonin properties

23
Q

What is the effect of vilazodone and vortioxetine on weight?

A

Weight neutral

24
Q

What is the MOA of bupropion?

A

NE and dopamine reuptake inhibitor

25
Q

What is the MOA of mirtazapine? What is it known for?

A

Alpha 2 blocker and serotonin blocker

Weight gain (good in cachectic patients)

26
Q

What is the MOA of trazodone?

A

Inhibition of 5HT2A receptors. Human and animal studies have demonstrated that inhibition of this receptor is associated with antianxiety, antipsychotic and antidepressant effects.

27
Q

What is the MOA of Quetiapine?

A

Atypical antipsychotic

28
Q

What is methylphenidate?

A

Ritalin (amphetamine)

29
Q

What is dextroamphetamine?

A

Adderall

30
Q

Which gender has an increased prevalence in bipolar disorder?

A

Neither–equally common

31
Q

What percent of patients who have had an episode of bipolar disorder will have another incidence?

A

90%

32
Q

True or false: there is no increase in the incidence of bipolar disorders in 1st degree relatives of patients with the disorder

A

False–increased

33
Q

What are the diagnostic criteria for bipolar disorder?

A

Requires the presence of manic or mixed episode–no depressive episode is required

34
Q

True or false: to be diagnosed with bipolar disorder, you do NOT need to have a depressive episode

A

True

35
Q

True or false: mania usually requires hospitalization

A

True

36
Q

Untreated episodes of mania usually last how long?

A

Few weeks to months

37
Q

What is the mean age of onset for bipolar disorder?

A

early 20s

38
Q

Do patients with manic episodes typically have insight into their disease?

A

no

39
Q

What usually precedes episodes of mania with bipolar disorder?

A

Psychosocial stressors

40
Q

What is a hypomanic episode?

A

Same s/sx as a manic episode, but less severe, and do not markedly impair functioning

41
Q

What is bipolar I disorder?

A

One or more manic or mixed episodes (no MDE required)

42
Q

What is bipolar II disorder?

A

At least one hypomanic episode and at least one depressive episode without any manic or mixed episodes

43
Q

What is cyclothymia?

A

2 years of fluctuating periods of hypomania and depressive symptoms that don’t meet full criteria for a hypomanic or major depressive episode

44
Q

Can anti-depressants cause manic episodes in patients with bipolar disorder?

A

Classically, yes, but most of the time they just don’t respond

45
Q

How efficacious is Li in the treatment of bipolar disorder?

A

Highly, but narrow therapeutic window

46
Q

What lifestyle change in indicated for bipolar treatment?

A

Sleep hygiene

47
Q

What is the treatment for manic episodes with bipolar?

A

Antipsychotics

48
Q

True or false: Li is neuroprotective

A

True

49
Q

What is the number 1 killer of bipolar patients?

A

CV disease

50
Q

What is the MOA of phenelzine?

A

MAOI

51
Q

What is the MOA of selegiline?

A

MAOI

52
Q

What are the diagnostic criteria for bipolar disorder? (7)

A
  • Flight of ideas
  • Inflated self-esteem
  • Distractibility
  • Goal directed activity increased
  • Excessive pleasurable activities
  • Talkativity
  • Sleep needs decreased

(FIDGETS)

53
Q

How many s/sx are needed from the criteria of bipolar disorder to qualify?

A

Three, but four needed if only irritable

54
Q

What non-pharmacotherapy treatment is recommended for bipolar disorder?

A

Good sleep hygiene

Psychiatry pro +1700 (28 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions