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therapeutics > MDD > Flashcards

MDD Flashcards

0
Q

Drugs used for pregnancy

A

TCA

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1
Q

Drugs used for insomnia

A

TCA

Trazadone

Mirtazipine

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2
Q

Drugs used for migraine

A

TCA

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3
Q

Fluoxetine

A

SSRI

Prozac

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4
Q

Sertraline

A

SSRI

Zoloft

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5
Q

Paroxetine

A

SSRI

Paxil

Used for menopause

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6
Q

Citalopram

A

SSRI

celexa

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7
Q

Escitalopram

A

SSRI

Lexapro

Enantiomer of celexa

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8
Q

Fluvoxamine

A

SSRI

Luvox

Has many ddi especially 1A2 2C9. 2C19

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9
Q

Trazadone

A

SARI

desyrel, oleptro

CU: insomnia -depression related anxiety - sexual dysfxn with other meds

CI : nonconpliant

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10
Q

Vilazadone

A

Viibryd

CU: mixed anxiety depression -lower incidence of sexual dysfxn - renal dysfxn weight neutral

CI : seizures

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11
Q

Bupropion

A

Wellbutrin

CU: add on for no response and reverse sexual dysfxn

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12
Q

Cons for bupropion

A 
Seizures 
Agitated/ insomnia 
Hepatic dysfxn 
Abrupt dc of alcohol and sedatives 
Those one NTS
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13
Q

Mirtazapine

A

Remeron
Mixed anxiety and depression
Mixed panic and depression

CI: seizures

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14
Q

Phenelzine

A

MAOI

Nardil

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15
Q

Tranyloypramine

A

MAOI

parnate

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16
Q

Elavil

A

Tertiary amine

Amitriptyline

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17
Q

Tofranil

A

Tertiary amine

Imipramine

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18
Q

Anafranil

A

Clomipramine

Tertiary amine

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19
Q

Sinequan

A

Tertiary amine

Doxepine

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20
Q

Surmontil

A

Trimipramine

Tertiary amine

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21
Q

Vivactil

A

Secondary amine

Protriptyline

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22
Q

Norpramin

A

Secondary amine

Desipramine

23
Q

Asendin

A

Secondary

Amoxapine

24
Q

Pamelor

A

Nortriptyline

Secondary

25
Q

Therapy duration for first episode

A

6- 9 months

26
Q

Therapy duration for second episode

A

4 to 5 years

27
Q

Duration of therapy for second episode with complicated factors and third episode

A

Indefinitely

28
Q

Electrocinvulsive therapy (ECT)

A

Most effective for treatment resistance

Preg

Pts who refuse to eat/drink

Delusional

29
Q

ECT duration

A

2 to 3 times weekly for 6 -12 treatments

30
Q

Drug used for nerve pain

A

Duloxetine (cymbalta)

31
Q

Medication used for pain

A

TCA

32
Q

Medication used for elderly

A

SSRI

33
Q

Medication used for bipolar

A

SSRI

34
Q

Medication for cardiac

A

SSRI

35
Q

Medication used for menopause

A

SSRI

Paroxetine

36
Q

Medication used for overweight

A

SSRI
Venlafaxine/ Desvenlafaxine
Bupropion causes anorexia

37
Q

Medication used for bulimia

A

MAOI

38
Q

Mediation used associated with panic attack

A

MAOI

Mirtazipine

39
Q

Reverse sexual dysfxn (add on)

A

Bupropion

Trazadone/ nefazodone

40
Q

Medications used with chemo

A

Mirtazipine

41
Q

Mediation used for renal dysfxn

A

Vilazodone

42
Q

Medication used for hypersomiacs ( excessive daytime sleepiness)

A

Venlafaxine/ desvenlafaxine

43
Q

Psychomotor retardation

A

Venlafaxine/ desvenlafaxine

44
Q

What medications can’t you give with hepatic dysfxn

A 
SSRI ( hepatic and renal) 
Mirtazipine 
Bupropion 
Nefazodone 
Duloxetine ( and hx alcohol use)
45
Q

Selegiline low concentration is used for ?

A

MAO B (CNS)

Parkinson’s disease

High con inhibits MAO A (depression and increase tyramine interactions )

46
Q

Bupropion side effects

A 
Anxiety 
Anorexia 
Agitation 
Nausea 
Insomnia 
Seizures ( high risk with head trauma, Cns tumor, bulimia/ anorexia , alcoholics )
47
Q

Bupropion DDI

A

Increase toxicity :
- amantadine - Levodopa - MAOI - ritonavir

Decrease toxicity: -CBZ - phenytoin- phenobarbital

Don’t use with NTS (Zyban)

48
Q

Medications that can not be used with hepatic dysfunction

A 
Bupropion 
Duloxetine 
Mirtazapine
SSRI
Trazadone ( nefazodone )
Vortioxetine
49
Q

What drug can not be given with even one drink of alcohol ?

A

Duloxetine( cymbalta )

Used for diabetic peripheral neuropathic pain ( dpnp)

50
Q

What medication can u give with renal dysfxn

A

Vilazadone

51
Q

Drug used for SUI (stress urinary incontinence )

A

Duloxetine

52
Q

What medication activates mania in bipolar patients ?

A

Venlafaxine/ desvenlafaxine

53
Q

What drugs can’t use use with HTN

A

Venlafaxine/ desvenlafaxine
Cymbalta (Duloxetine )
Fetzima (levomilnacipran) increase bp

54
Q

What medication can’t we use for hypotension

A

MAOI

TCA

55
Q

What medications can’t u use with seizures

A

Bupropion
Vilazodone
Mirtazapine

TCA - adverse effect

56
Q

What medications can’t u use with sexual dysfxn

A

SSRI
Duloxetine
Venlafaxine/ desvenlafaxine
Levomilnacipran

therapeutics (4 decks)

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