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therapeutics > Bipolar > Flashcards

Bipolar Flashcards

0
Q

Divalproex DDI

A
  • LTG- increase LTG
  • CBZ - CBZ toxicity
    Potentiates anticoagulant effects with warfarin
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1
Q

Lithium ddi

A

CBZ
Haloperidol

Ace diuretics NSAIDs sodium depletion- inc li

Sodium supp - decrease li

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2
Q

CBZ Drug interactions

A
  • clozapine bc seizures and agranulocytosis
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3
Q

Lithium adverse effects

A 
Fine tremors 
Leukocytosis 
Goiter hypothyroidism
Weight gain
Polyuria
Nephrogenic DI
Teratogenic 
Acne
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4
Q

Lithium toxicity

A 
Coarse tremors 
Seizures
Coma 
Slurred speech 
Hypotension
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5
Q

Valproic acid adverse effects

A 
Hair loss 
Tremors 
Pancreatitis 
Hepatotoxicity 
Teratogenic 
Thrombocytopenia
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6
Q

CBZ adverse effects

A 
Ataxia confusion 
Thrombocytopenia 
Anemia 
SIADH ( not peeing enough)
Elected LFTS
Rash- HLAB 1502 - Asian
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7
Q

Quetiapine

A

Seroquel
Antipsych

Bipolar depression
Bipolar mania

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8
Q

Symbyax

A

Olanzapine and fluoxetine

Bipolar depression

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9
Q

Ziprasidone

A

Geodon

Antipsych

Manic

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10
Q

Aripirazole

A

Abilify

Mania

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11
Q

Asenapine

A

Saphris

Bipolar mania

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12
Q

Lurasidone

A

Latuda

Bipolar depression

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13
Q

What two drugs can cause rash

A

LTG and CBZ

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14
Q

LTG ( lamictal) risk of rash increased by

A

High dose

Use with Valproic acid

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15
Q

8 Drugs that can cause bipolar

A 
Antidepressants 
Anticholinergics 
Cocaine 
Corticosteroids 
Decongestants
Ephedra
L-dopa
Sympathomimetics
16
Q

What assessment tool do u use for bipolar

A

Young mania rating scale ( YMRS)

  • without psychotic features
  • with psychotic features
17
Q

Equetro / tegretol

A

Carbamazepine

18
Q

Monitoring for lithium

A

Renal
Urinary analysis

Long term : renal fxn every 6 to 12 weeks

19
Q

All common mood stabilizer monitoring conditions

A 
CBC +chem
Preg
Urinary drug screen 
EKG >40
Med hx and PE
TFTs (thyroid )
20
Q

All common mood stabilizer monitoring for short term (first two months) and long

A

Short: serum level every 1 -2 w

Long : serum level every 3-6 months

21
Q

Monitoring for Valproic acid

A

LFTs

First two m: CBCs, LFTs monthly

Long term : CBCs, LFTs q6-12 m

22
Q

Monitoring for CBZ

A

LFTs
Electrolytes
Renal fxn

First two months : CBC LFTs monthly

Longterm: CBC LFTs q 6-12 months

therapeutics (4 decks)

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