MCQs Flashcards
Which of the following antibiotics inhibit cell wall synthesis by binding to transpeptidase (PBP) and preventing peptidoglycan cross-linking?
A) Macrolides
B) Beta-lactams
C) Tetracyclines
D) Aminoglycosides
Answer: B
A) Macrolides - Binds to 50s ribosome
C) Tetracyclines - Bind to 30s ribosomal subunit.
D) Aminoglycosides - Binds to 30s ribosomal subunit.
Which antibiotic class can cause nephrotoxicity and ototoxicity as common adverse effects?
A) Macrolides
B) Aminoglycosides
C) Glycopeptides
D) Sulfonamides
Answer: B
A) Macrolides - GI upset (nausea, vomiting)
C) Glycopeptides - Nephrotoxicity and Redman syndrome but not ototoxicity.
D) Sulfonamides - Associated with hypersensitivity reactions and hematological effects.
Which of the following drugs is a protein synthesis inhibitor that binds to the 50s ribosomal subunit and prevents protein elongation?
A) Linezolid
B) Gentamicin
C) Ciprofloxacin
D) Doxycycline
ANS: A) Linezolid
B) Gentamicin - 30s
C) Ciprofloxacin - Quinolone,disrupts DNA synthesis.
D) Doxycycline - 30s
Which of the following is a beta-lactam antibiotic?
A) Clindamycin
B) Amoxicillin
C) Ciprofloxacin
D) Doxycycline
Answer: B
A) Clindamycin - Lincosamide class.
B) Amoxicillin - Beta-lactam class.
C) Ciprofloxacin - Quinolone class.
D) Doxycycline - Tetracycline class.
Which antibiotic belongs to the glycopeptide class and is often used to treat MRSA infections?
A) Vancomycin
B) Azithromycin
C) Gentamicin
D) Linezolid
Answer: A
A) Vancomycin - Glycopeptide class.
B) Azithromycin - Macrolide class.
C) Gentamicin - Aminoglycoside class.
D) Linezolid - Oxazolidinone class.
Which of the following drugs is a quinolone antibiotic?
A) Tetracycline
B) Sulfamethoxazole
C) Levofloxacin
D) Metronidazole
Answer: C
A) Tetracycline - Tetracycline class.
B) Sulfamethoxazole - Sulfonamide class.
C) Levofloxacin - Quinolone class.
D) Metronidazole - Nitroimidazole class.
Which antibiotic is a macrolide commonly used to treat respiratory infections?
A) Erythromycin
B) Amikacin
C) Sulfadiazine
D) Ciprofloxacin
Answer: A
A) Erythromycin - Macrolide class, used for respiratory infections.
B) Amikacin - Aminoglycoside class.
C) Sulfadiazine - Sulfonamide class.
D) Ciprofloxacin - Quinolone class.
Which of the following is a tetracycline antibiotic?
A) Clarithromycin
B) Doxycycline
C) Penicillin G
D) Ceftriaxone
Answer: B
A) Clarithromycin - Macrolide class.
B) Doxycycline - Tetracycline class.
C) Penicillin G - Beta-lactam class.
D) Ceftriaxone - Beta-lactam class (Cephalosporin).
Which antibiotic is known to cause “Red Man Syndrome” if infused too rapidly?
A) Linezolid
B) Cefazolin
C) Vancomycin
D) Clindamycin
Answer: C) Vancomycin
Which antibiotic is both a folate synthesis inhibitor and can cause Stevens-Johnson Syndrome as an adverse effect?
A) Vancomycin
B) Sulfadiazine
C) Doxycycline
D) Gentamicin
ANS: B) Sulfadiazine
Which of the following drugs is associated with pseudomembranous colitis as a side effect?
A) Clindamycin
B) Amikacin
C) Vancomycin
D) Cefazolin
ans: A) Clindamycin
Which of the following antibiotics is contraindicated in pregnant women due to the risk of fetal bone and teeth abnormalities?
A) Vancomycin
B) Ceftriaxone
C) Doxycycline
D) Azithromycin
C) Doxycycline
Which of the following antibiotics is most likely to cause ototoxicity and nephrotoxicity in a patient with renal impairment?
A) Clindamycin
B) Vancomycin
C) Metronidazole
D) Gentamicin
D) Gentamicin
