MCQbank SBAs Flashcards
Chloramphenicol rare side effect
Bone marrow suppression
carcinoid tumours vitamin deficiency
Niacin - pellagra
(increased tryptophan metabolism - niacin is derived from tryptophan)
Waldenstrom’s Macroglobulinaemia is associated with
Non-Hodgkin’s Lymphoma
P450 inhibitors i.e INCREASE drug level
SICKFACES.COM Group
Sodium Valproate
Isoniazid
Cimetidine
Ketoconazole
Fluconazole
Alcohol
Ciprofloxacin
Erythromycin
Sulphonamides
Chloramphenicol
Omeprazole
Metronidazole
Grapefruit Juice
P450 inducers i.e. DECREASE drug level
CRAP GPS
Carbamazepine
Rifampicin
Alcohol
Phenytoin
Griseofulvin
Phenobarbatone
Sulphonylurea
DMARD causing reduced visual acuity
Hydroxychloroquine
roseola infantum is caused by
HHV-6
‘sixth disease’
Myasthenia gravis treatment (in mild disease)
Pyridostigmine (acetylcholinesterase inhibitor)
SLE antibodies
ANA (screening, sensitivity 95%)
Anti-dsDNA
Anti-Sm (most specific, sensitivity only 30-40%)
Fragile X syndrome inheritance
X-linked dominant
Paeds: Murmurs occuring during …….. are always pathological
Diastole
Sodium valproate in early pregnancy is associated with
neural tube defects
Acute otitis media is most commonly caused by
RSV
Most common childhood epilepsy
Benign rolandic epilepsy
Treatment for Onychomycosis
Terbinafine
Centor criteria for ?abx in pts presenting with sore throat
Tonsillar exudate
Absence of cough
Fever
Lymphadenopathy
if >=3 present -> 50% chance 2ndry to Group A strep
10 days phenoxymethylpenicillin
What is Uhthoff’s phenomenon
Worsening of symptoms in demyelinating conditions with increase in temperature e.g. hot weather, exercise
Cause of pneumonitis in rheumatoid patient
Methotrexate pneumonitis
most common cause of septic arthritis
Staph aureus
sarcoidosis causes a …….. ventilatory defect
restrictive
CML monoclonal antibody treatment
Imatinib (against philadelphia chromosome)
Hyperthyroid treatment in pregnancy
1st timester PTU
2nd and 3rd CBZ
HLA-B27 association
Ank Spond
lower back pain improving with exercise
Ank Spond
diagnosis of carcinoid syndrome
urinary 5-hydroxyindoleacetic acid (5-HIAA)
Slapped cheek syndrome otherwise known as, caused by
Erythema infectiosum, fifth disease, parvovirus B19 infection
Viagra side effect - vision
Blue discolouration
Down and out, blown pupil
CN III lesion - extrinsic compression e.g. PICA aneurysm
sickle cell disease causes a ………. anaemia
normocytic
vitamin deficiency: cracked red lips, angular cheilitis, inflammation of mouth and tongue
Riboflavin
Vit B2
how long can a patient be legally detained for with a section 5(2)
72hrs
BP treatment caucasian <55
ACEi
Average age diagnosis 23, SBO/intussusception, pigmented lesions buccal mucosa, GI polyps
Peutz-Jeghers syndrome
Autosomal dominant
History of gout, worsening of symptoms following introduction of anti-hypertensive agent
Thiazide diuretic e.g. bendroflumethiazide
Friedrich’s ataxia most likely cause of death
Cardiomyopathy
koplik spots are associated with
Measles
Antibody found commonly in Primary biliary cirrhosis
Anti-mitochondrial antibodies
Spleen prevents infection by ……… bacteria
encapsulated e.g. strep pneumoniae, strep pyogenes, meningococcus, group b strep
Max dose of simvastatin in patients on Amlodipine
20mg
Amlodipine is weak cytochrome p450 inhibitor
Wet/exudative Age-related Macular Degeneration is characterised by
Choroidal neovascularisation
Absence seizure treatment
Ethosuximide
Lamotrigine
Valproate
Antistreptolysin 0 titres are raised in
Henoch-Schonlein purpura
Treatment for Bell’s palsy
50mg Pred OD 10 days if presents within 72hrs
How to distinguish Labyrinthitis and vestibular neuronitis
Labyrinthitis likely to present with tinnitus/deafness
This does not occur in vestibular neuronitis
Most common side effect of sulphonylureas e.g. Gliclazide
Hypoglycaemia
Normal-pressure Hydrocephalus triad
Gait Disturbance
Urinary Incontinence
Dementia
Pellagra-like dermatitis (red, scaly photosensitive rash), neurological involvement (ataxia, dysarthria, tremors, spasticity)
Hartnup disease (inborn error of metabolism)
What is a Pterygium
Benign wedge-shaped growth of conjunctiva extending from nasal side
Drug that worsens glycaemic control
Thiazide diuretics
How many days after conception is urine pregnancy test positive
9
Stage 2 hypertension, black/african-caribbean, any age
Ca2+ blocker
Large erythematous herald patch followed by appearance of collection of smaller patches
Pityriasis Rosea
Hand foot mouth causative organism
Coxsackie A16
Haemochromatosis triad
Diabetes
Cirrhosis
Skin pigmentation
Horner’s syndrome triad
Miosis
Ptosis
Enopthalmos
Pancoast tumour pathophysiology
Apical lung tumour that can compress sympathetic chain causing Horner’s syndrome
Commonest cause of sciatica
Herniated intervertebral disc
B2-MICROglobulin is associated with
Multiple myeloma
Increased red cell osmotic fragility
Hereditary spherocytosis
Drug causing increased saliva
Clozapine
Neostigmine
Primary biliary cirrhosis antibody
Anti-MITOCHONDRIAL antibody
Anion gap equation
(Na+K) - (Cl+HCO3)
First line treatment of Generalised tonic clonic seizures
Sodium Valproate
UNLESS female of reproductive age
Shawl/cape-like distribution of pain and temperature sensory loss over arms, trunk, shoulders
Syringomyelia
(fluid filled tubular cavitation)
Cancer risk COCP
Increased risk BREAST & CERVICAL cancer
Drug causing pulmonary fibrosis and corneal deposits
Amiodarone
Laxative - stains urine red
Co-danthramer
Severely painful red eye in association with a connective tissue disorder in a middle-aged woman
Scleritis
N.b. association with Rheumatoid arthritis
POP - one pill missed - management
Take missed pill now, condoms for 48hrs
Bupropion mechanism of action
Nicotinic antagonist
Noradrenaline and dopamine reuptake inhibitor
Bupropion mechanism of action
Nicotinic antagonist
Noradrenaline and dopamine reuptake inhibitor
Short stature, short neck, short 4th and 5th metacarpals
Pseudohypoparathyroidism - resistance to PTH
Low calcium
High phosphate
High PTH
Lupus vulgaris is caused by
Cutaneous tuberculosis infection
Stage 1 hypertension
140/90 - 160/100
ABPM 135/85 - 150/95
Stage 2 hypertension
160/100 - 180/120
ABPM >150/95
Stage 3 hypertension
BP >180/120
Accelerated hypertension
> 180/120 with end-organ damage
Effect of Tamoxifen on bone health
Reduces risk of osteoporosis - acts as oestrogen agonist in bone
Lambert eaton syndrome pathophysiology
Paraneoplastic.
Antibodies against pre-synaptic calcium channels in NMJ
Causes limb muscle weakness
Medication that can precipitate an acute gout flare
Allopurinol
Pulmonary oedema and sensorineural deafness association
LOOP DIURETICS can be ototoxic
Meniere’s triad
Tinnitus
Vertigo
Hearing loss
Bright green fluorescence after congo-red staining
Amyloidosis
IBD drug causing oligospermia
Sulfasalazine
Congenital rubella triad
Sensorineural hearing loss
Congenital heart defects - PDA, pulmonary artery stenosis
Ocular defects - cataracts, retinopathy
Commonest cause of severe diarrhoea in HIV positive patients
Cryptosporidium
Marcus Gunn pupil
RAPD
Low levels of C1 inhibitor
Hereditary angioedema
Toxoplasmosis - host
Cats
When is mid-luteal progesterone tested
1 week before period starts
osler weber rendu otherwise known as
Hereditary haemorrhagic telangiectasia
