MCQ bank Flashcards
What staining is associated with amyloid?
Congo red staining will be positive (there will be bright green fluorescence staining)
How might PCKD present?
HTN, haematuria, flank pain, stroke, renal failure, palpable renal masses
Can renal amyloidosis present with masses?
Yes
What is pseudomembranous colitis caused by?
C.diff
What SEs of statins are there?
Myositis
Raised LFTs
Gallstones
Interstitial lung disease in rare cases
Ottawa rules (for XRAY) of knees?
Tenderness at head of fibula
Cannot flex to 90 degrees
Age =>55
Isolated tenderness of patella
What is peuts-jeghers syndrome?
Genetic syndrome associated with intestinal polyps
What conditions are associated with nasal polyps?
Asthma
Aspirin hypersensitivity
CF
Allergic rhinitis
Most common cause of CAP?
Strep pneumonia
Drugs used in Alzheimers?
Donepezil and memantine
Also use rivastigmine and galantamine
Management of COPD exacerbation?
Admit if severe.
Salbutamol nebs
Pred course
Abx if sputum positive or consolidation present
O2 to maintain sats >90
If unwell despite this - (acidotic) you would consider NIV (BiPAP)
If still unwell - ITU
How would diabetes insipidus present?
Excessive thirst and excretion of large volumes of diluted urine
High serum sodium and low urine osmolarity, high serum osmolarity
In severe cases may have seizures due to electrolyte disturbance
Causes of diabetes insipidus and results of fluid deprivation test and ADH?
Nephrogenic
- Insensitivity to ADH
- Fluid deprivation - will fix serum osmo (<300)
- ADH will not fix
- Can be caused by CKD/Lithium, congenital
Cranial
- Not producing ADH
- Fluid deprivation and ADH will fix osmo
Most common type of glomerulonephritis for adults?
IgA nephropathy (Bergers disease)
How does IgA glomerulonephritis present and how can you differentiate that from post strep GN?
Presents with nephritis syndrome (haematuria) 1-2 days after URTI
Post strep presents 1-3 weeks after
In what ways do GN disease present?
Nephritic syndrome (haematuria and low level protein, oliguria and HTN) Nephrotic syndrome (Proteinuria and oedema) Mixed picture
What GN’s causes a Nephritic picture? (most common and others in there)
Most commonly in adults: IgA nephropathy (typically men in 20s or 30s, 1-2 days afetr URTI)
Most commonly in children: Post strep GN (1-2 weeks after URTI)
Granulomatitis with polyangitis
- would have systemic features
Eosinophilic Granulomatitis with polyangitis
- associated with asthma and systemic features
Goodpasture
- pulmonary haemorrhage
Allport
- inherited
- sensorineural and eye disease
Thin basement membrane disease
- Inherited
What GNs cause a mixed picture?
Membranoproliferative
Diffuse proliferative
What GNs cause a nephrotic picture?
Most common in children: Minimal change,
- Idiopathic or caused by infection/drugs
Most common in adults: Focal segmental
- idiopathic or HIV
Diabetic nephropathy
Amyloidosis
On spirometry how can you differentiate asthma and COPD?
Asthma may have a normal or increased DLCO and a normal TLC
COPD would have a decreased DLCO and an increased TLC
XRAY changes for RA?
Soft tissue swelling
Juxta articular deminerlisation
Joint pace narrowing
Erosions
What virus is associated with nasopharnygeal carcinoma?
EBV
Common mechanism of injury of a calcaneal fracture?
jump or fall from high height
How to estimate plasma osolarity?
2x sodium plus glucose and urea