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PATHO B2 > MCQ > Flashcards

MCQ Flashcards

1
Q

IL-4. asthma

A

stimulate ig E prod

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2
Q

IL-5 asthma

A

activate eosionophils

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3
Q

IL-13 asthma

A

stimulate muscus secretion fr bronchial submucosal glands n promote igE prod

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4
Q

asthma leukotrienes C4,D4,E4

A

cause prolong bronchoconstriction,increase vascular permeability,increase mucus secretion

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5
Q

asthma Ach

A

constriction of airway SM

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6
Q

asthma Galectin 10

A

released fr eosinophils
froms Charcot-Leyden crystals

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7
Q

who is prone to severe TB infection

A

AIDS
Immunosuppresed
Inherited IL-12 receptor mutation—MENDELIAN SUSCEPTIBILITY TO MYCOBACTERIAL DISEASE

polymorphism in NRAMP1 gene—-disease pregress due to absent immune response

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7
Q

receptors for TB entry

A

MBL, C3 complement receptor

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8
Q

TLR2 N IL-12 PROD FR

A

DENDRITIC CELLS

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9
Q

erosion of pulmonary art indicate

A

miliary tb in both lungs

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10
Q

erosion of pulmonary vein indicates

A

systemic miliary spread

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11
Q

Miliary TB resistent sites

A

HEART
STRIATED MUSCLES
THYROID
PANCREAS

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12
Q

ADENOCARCINOMA MARKER

A

TTF-1,NAPSIN-A

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13
Q

SQUAMOUS CELL MUTATION N MARKER

A

mutation: TP53, CDKN2A INACTIVATION
markers:P40,P63

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14
Q

SMALL CELL CARCINOMA MARKERS

A

-neuroendorine marker:chromogranin,synaptophysin,CD56
other:NSE

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15
Q

BRCA 1

A

CH 17

16
Q

BRCA 2

A

CH 13

17
Q

HERIDITARY BREAST CANCER

A

CKEK2 DELETION

18
Q

COWDEN’S SYNDROME

A

PTEN GERMLINE MUTATION

19
Q

ILC

A

loss of CDH 1 gene expression
loss of E cadherin
loss of cohesiveness

20
Q

what macrophage relaese on gout

A

IL-1 beta

21
Q

what neutrophil release in gout

A

LTB4,PG,FREE RADICALS

22
Q

RETINOBLASTOMA GENE

A

CH 13

23
Q
A

PATHO B2 (4 decks)

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