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Pat 210 > MCQ > Flashcards

MCQ Flashcards

1
Q

2- What is the mechanism of action of lactulose as a purgative?

A

d. It increases bulk of intestinal contents by osmosis

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2
Q

3- Which of the following is an opiate anti-motility agent with minimal crossing
of the blood-brain barrier and used in treatment of diarrhea ?

a. Kaolin
b. Loperamide
c. Mebeverine
d. Propantheline

A

b. Loperamide

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3
Q

6- Which of the following is an antacid that can cause constipation and
hypophosphatemia?

a. Aluminum hydroxide gel
b. Magnesium trisilicate
c. Sodium bicarbonate
d. Calcium carbonate

A

a. Aluminum hydroxide gel

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4
Q

15- Regarding the eradication of helicobacter bacteria, all of the following antimicrobials can be used EXCEPT:

a- Clarithromycin
b- Metronidazole
c- Amoxicillin
d- Gentamycin

A

d- Gentamycin

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5
Q

17- As regard prokinetic agents, which of the following is FALSE:

a- Domperidone has dual anti-emetic & prokinetic effects
b- Metoclopramide is effective in motion sickness
c- Erythromycin stimulates motilin receptors on GIT
d- Itopride & Mosapride stimulate 5-HT4 receptors in enteric ganglia

A

b- Metoclopramide is effective in motion sickness

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6
Q

19- Regarding the role of drugs acting on neurokinin receptors in the control of vomiting, which of the following statements is true?

a- Neurokinin receptor blockers are particularly useful in vomiting of pregnancy.
b- Aprepitant is one of the commonly used blockers of these receptors.
c- Tumor Necrosis Factor (TNF) can stimulate these receptors.
d- These receptors are effectively blocked by palonosetron.

A

b- Aprepitant is one of the commonly used blockers of these receptors.

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7
Q

20- Which of the following is an opiate anti-motility agent with minimal crossing of the blood-brain barrier and used in treatment of diarrhea ?

a- Loperamide
b- Mebeverine
c- Propantheline
d- Kaolin

A

a- Loperamide

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8
Q

22- Regarding the mucosal protective Misoprostol, which of the following statements is true?

a- It is an anti-prostaglandin for the treatment of fever
b- It can produce abortion in pregnant woman
c- It is a spasmolytic used for the treatment of colic
d- It is an antiplatelet agent

A

b- It can produce abortion in pregnant woman

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9
Q

23- Which of the following is a new intravenous antiemetic that has great affinity for 5-HT3 receptors and a long serum half-life of 40 hours?

a- Metoclopramide
b- Ondansetron
c- Dronabinol
d- Palonosetron

A

d- Palonosetron

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10
Q

27- Which of the following explains the beneficial effect of kaolin in the
treatment of diarrhea?

a- It stimulates opiate receptors in GIT
b- It blocks muscarinic receptors in GIT
c- It adsorbs toxic substances and provides a coating for the intestine
d- It releases tannic acid in intestine and precipitates surfaces proteins

A

c- It adsorbs toxic substances and provides a coating for the intestine

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11
Q

28- If the investigations for a case of peptic ulcer showed H. pylori infection, the proper triple therapy regimen for the eradication is:

a- Omeprazole+ Amoxicillin + Cefoperazone
b- Omeprazole + Amoxicillin + Tetracycline
c- Omeprazole + Amoxicillin + Clarithromycin
d- Omeprazole+ Amoxicillin + Metronidazole

A

c- Omeprazole + Amoxicillin + Clarithromycin

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12
Q

29- Which of the following mucosal protective drugs has an additional
bactericidal effect against H. pylori?

a- Sucralfate
b- Misoprostol
c- Colloidal bismuth
d- Carbenoxolone

A

c- Colloidal bismuth

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13
Q

31- Which of the following antidiarrheal drugs exerts its action by adsorbing toxic substances?

a. Diphenoxylate
b. Propantheline
c. Charcoal
d. Mebeverine

A

c. Charcoal

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14
Q

38- Which of the following is an important difference between cimetidine and ranitidine?

a. Cimetidine has a longer half-life.
b. Ranitidine has fewer drug interactions.
c. Only ranitidine blocks H2 receptors.
d. Only ranitidine crosses the blood brain barrier

A

b. Ranitidine has fewer drug interactions.

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15
Q

42- Which of the following is a prokinetic agent?

a. Itopride
b. Mebeverine
c. Alosetron.
d. Diphenoxylate

A

b. Mebeverine

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16
Q

43- One of the following drugs is paired with a relevant action:

a- Magnesium trisilicate - Irreversible inhibition of parietal H+/K+ ATPase
b- Ranitidine - Histamine H₂ receptor blocker
c- Pantoprazole - Chemical and physical antacid
d- Dimenhydrinate - Blocks D₂ receptors in CTZ

A

b- Ranitidine - Histamine H₂ receptor blocker

17
Q

45- Indicate which drug might interact with antiplatelet effect of clopidogrel:

a- Omeprazole
b- Famotidine
c- Rabeprazole
d- Pirenzepine

A

a- Omeprazole

18
Q

47- The following purgative is used with neomycin in treatment of hepatic encephalopathy:

a- Methyl-cellulose
b- Lactulose
c- Bisacodyl
d- Croton oil

A

b- Lactulose

19
Q

48- The following purgative causes lipid pneumonia if it reaches the lung:

a- Liquid paraffin
b- Mediyi cellulose
c- Lactulose
d- Magnesium sulphate

A

a- Liquid paraffin

20
Q

50- Drug that activates mu opioid receptors in enteric nervous system and used in treatment of diarrhea is:

a- Propantheline
b- Atropine
c- Loperamide
d- Dicyclomine

A

c- Loperamide

21
Q

54- Anorexigenic drug that decrease the uptake of noradrenaline (NA) and serotonin (5-HT) in hypothalamus is:

a- Sibutramine
b- Lorcaserin
c- Metformin
d- Liraglutide

A

a- Sibutramine

22
Q

56- Which of the following is a long-acting selective beta 2 agonist given by inhalation?

a. Salmetrol
b. Terbutaline
c. Salbutamol
d. Bambuterol

A

a. Salmetrol

23
Q

58- Which of the following is a central antitussive used in the treatment of chronic non-productive cough?

a. Loratadine
b. Bromhexine
c. Acetylcysteine
d. Dextromethorphan

A

d. Dextromethorphan

24
Q

59- Which of the following is a leukotriene receptor antagonist?

a. Zileuton
b. Omalizumab
c. Zafirlukast
d. Ciclesonide

A

c. Zafirlukast

25
Q

61- Each of the following drugs used in bronchial asthma is matched with its mechanism of action EXCEPT:

a) Tiotropium Anti-muscarinic drug
b) Omalizumab Anti-IgE Monoclonal Antibody
c) Cromolyn Mast Cell Stabilizer
d) Zileuton Beta-2 agonist

A

d) Zileuton Beta-2 agonist

26
Q

63- All the following about anti-cough remedies are true, EXCEPT:

a) Potassium iodide is a saline expectorant
b) Dextromethorphan is a Non-narcotic central antitussive
c) Acetylcysteine is a mucolytic agent used in acetaminophen toxicity
d) Bromhexine is a peripheral antitussive

A

c) Acetylcysteine is a mucolytic agent used in acetaminophen toxicity

27
Q

65- Which of the following anti-asthma drugs needs therapeutic monitoring of plasma concentration?

a. Tiotropium
b. Budesonide
c. Salmeterol
d. Theophylline

A

d. Theophylline

28
Q

67- Which of the following is a leukotriene receptor antagonist?

a. Omalizumab
b. Zileuton
c. Montelukast
d. Ciclesonide

A

c. Montelukast

29
Q

69- Which of the following is a long-acting selective beta 2 agonists given by inhalation?

a. Terbutaline
b. Formoterol
c. Salbutamol
d. Isoproterenol

A

b. Formoterol

30
Q

70- The following mucolytic is used as antidote in acetaminophen toxicity:

a) Dornasa alfa
b) Bromhexine
c) Acetylcysteine
d) Erdosteine

A

c) Acetylcysteine

31
Q

71- The following antitussive is suitable for treatment of dry irritant cough:

a) Benzonatate
b) Tincture ipecacuanha
c) Acetylcysteine
d) Bromhexine

A

b) Tincture ipecacuanha

32
Q

73- Asthma medicine that can binds IgE & prevents its binding to IgE receptors on mast cells:

a) Salbutamol
b) Omalizumab
c) Theophylline
d) Corticosteroids

A

b) Omalizumab

33
Q

78- A 60-year-old male with chronic obstructive lung disease is given
ipratropium as part of his therapeutic regimen. What is the mechanism of action of ipratropium?

a) Block of airway muscarinic receptors
b) Inhibition of 5-lipoxygenase enzyme
c) Inhibition of mediator release
d) Inhibition of phosphodiesterase enzyme

A

a) Block of airway muscarinic receptors

34
Q

79- Asthma medicine that can binds IgE and prevents its binding to IgE receptors on mast cells:

a) Salbutamol
b) Omalizumab
c) Theophylline
d) Corticosteroids

A

b) Omalizumab

35
Q

80- Medications that can trigger asthma include all the following EXCEPT:

a) Pilocarpine
b) Propranolol
c) Diclofenac
d) Theophylline

A

d) Theophylline

36
Q

84- Which of the following is a mucolytic agent used in treatment of cough?

a) Loratadine
b) Dextromethorphan
c) Acetylcysteine
d) Benzonatate

A

d) Benzonatate

37
Q

85- Which of the following anti-asthmatic drugs inhibits lipoxygenase enzyme and results in inhibition of leukotrien synthesis?

a) Omalizumab
b) Zileuton
c) Montelukast
d) Ciclesonide

A

b) Zileuton

38
Q

86- Which of the following is a long-acting selective beta 2 agonist given by inhalation?

a) Salmetrol
b) Terbutaline
c) Salbutamol
d) Isoproterenol

A

a) Salmetrol

39
Q

87- Which of the following is a bronchodilator that acts by blocking the
muscarinic receptors and usually used in the treatment of chronic obstructive pulmonary disease?

a) Omalizumab
b) Formoterol
c) Fluticasone
d) Ipratropium

A

d) Ipratropium

Pat 210 (4 decks)

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