MCP: Vaccines Flashcards
Influenza Vaccines
- Inactivated (IIV)
- Live Attenuated
- FluMist
- Recombinant Hemagglutinin (RIV)
- FluBlock
Influenza Egg Allergy
- Hives or less: may administer and observe for 30 min
- Intranasal no egg data
- Recombo (FluBlock) is egg free; pt criteria and 18-49 yo
Egg Based Trivalent IIV3 (matching)
- Afluria, Agriflu, Flarix-IIV3, FluLaval, Fluvirin, Fluzone
Egg Based Quadrivalent IIV4
- Fluarix
- Additional B coverage
Flu Vaccine Schedule and Target Populations
- Annual
- 1st time/those not get 2 dose previous year (6mo-8yr), administer 2 dose separated by 4 wk
- High risk population
- greater than 50
- Heart, pulmonary, diabetes, healthcare, preganant, etc.
- Anyone greater than 6 mo
Ages and Which Flu Vaccine
- Fluzone: indication starts at 6 mo
- Fluzone High Dose >65
- Fluzone ID: 18-64 (10-15 degree vaccine)
IIV Flu Vaccine: CI, Precaution, SE,
- Contraindications
- Egg allergy/Vaccine Component
- Moderate or severe illness
- Precaution
- GBS in 6 wks
- SE
- Site irriation
- Fever, malasie (rare)
LIAV: Name, Target population, SE
- FluMist (quadrivalent this year)
- 2-49 yo; high risk populations
- SE: headache, nasal congestion, sore throat
LAIV: CI
- Severe allergic rxn egg/vaccine
- Moderate/severe illness
- <2 yo or >50, immunocompromised, pregant
- Children <5 with wheezing
- Children on long term aspirin
- Current nasal congestion
LAIV: Precaution, Concurrent Admin
- Precaution
- GBS in 6 wks
- Avoid severely immunocompromides for 7 days
- Concurrent Admins
- Same day or 4 wks
- TB test >4 wk after live
- LAIV not given until 48 hours after antiviral therapy stopped
- If antiviral in 2 wks of vaccine, redose
LAIV: Admin
- 1/2 sprayer into each nostril. Sneezing afterwards still confers immunity
- Expiration date
- Remove rubber
- Keep stopper
- Rapid admin
RIV: Advantage/Disadvantage
- Advantage:
- Fast production in pandemics
- Not depend on egg
- Disadvantage:
- Narrow age (18-49)
- Shorter shelf life (16 wk expire from production date)
Shingles: Name, Administartion, Concurrent Admin, Target population/schedul
- Zostavax
- Live Vaccine
- Administer SubQ
- Decreased effectiveness if given with PPSV23, but still give
- Adminster other live vaccine 4 wk apart
- Perform TB testing >4 wks
- Population
- 1 dose at >60
- FDA now approve >50
Shingles: SE
- Local reaciton
- No fever/serious rxn
Shingles: Precautions
- Current treatment with anti-viral against herpes (acyclovir)
- Avoid antivirral therapy a day before and 14 days after
- Cover any rash
Shingles: Contraindication/Storage
- Immunosuprresion
- Pregnancy (>4wk)
- Anaphylaxis to vaccine
- Moderate/severe illness
- Storage
- Freezer
- Dilutent at room temp or fridge
- Discard in not used within 30 minutes of reconstitution
Shingles Additional Information
- Only reduces occurrence of shingles by 50%
- Boosting not recommended
- Proper age range
Pneumonia: Who is at most risk
- Age 65 or older
- Diabetes Mellitus
- Cancer
- Cigarette smoking
Pneumococcal Polysaccharide Vaccine: Name and Example. Who not effective in. What it is for
- PPSV23 or Pneumovax
- Capsular Material
- 85-90% cases
- Not effective in <2 yo
- NOT prevent pneumonia but prevent further complications
PPSV: Concurrent Adminster, what is type
- Potential for decreased shingles
- NOT changed recommendation
- Inactivated bacteria
PPSV: Schedule/Revaccination
- Schedule:
- Adults 65 or older
- >2 if risks like pulmonary, asplenia, renal failure, immunocompromised
- >19 if asthma/cigs
- Revaccination:
- Routinely not recommended
- Recommended for those >2 at risk of infection
- >65 if recieved first dose before 65
- 5 years after the first dose
Pneumonia conjugate vaccine: Name, type, people
- PCV13 or Prevnar 13
- Capsular material
- Covalently linked to a nontoxic protein
- Protein helps children regonition
- New recommendtation in adults
- Type: inactivated
PCV: Schedule
- Children at 2, 4, 6, 12-15 months
- Childern who recieved PPSV23 previously also should recieve the recommended PCV13
PCV: Side Effects, CI
- SE:
- Local reaction
- Fever, myalgia
- CI:
- Anaphylaxis to vaccine component
- Moderate or severe illness