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Pharm 586 > MCP: Vaccines > Flashcards

MCP: Vaccines Flashcards

1
Q

Influenza Vaccines

A
  • Inactivated (IIV)
  • Live Attenuated
    • FluMist
  • Recombinant Hemagglutinin (RIV)
    • FluBlock
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2
Q

Influenza Egg Allergy

A
  • Hives or less: may administer and observe for 30 min
  • Intranasal no egg data
  • Recombo (FluBlock) is egg free; pt criteria and 18-49 yo
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3
Q

Egg Based Trivalent IIV3 (matching)

A
  • Afluria, Agriflu, Flarix-IIV3, FluLaval, Fluvirin, Fluzone
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4
Q

Egg Based Quadrivalent IIV4

A
  • Fluarix
  • Additional B coverage
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5
Q

Flu Vaccine Schedule and Target Populations

A
  • Annual
  • 1st time/those not get 2 dose previous year (6mo-8yr), administer 2 dose separated by 4 wk
  • High risk population
    • greater than 50
    • Heart, pulmonary, diabetes, healthcare, preganant, etc.
    • Anyone greater than 6 mo
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6
Q

Ages and Which Flu Vaccine

A
  • Fluzone: indication starts at 6 mo
  • Fluzone High Dose >65
  • Fluzone ID: 18-64 (10-15 degree vaccine)
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7
Q

IIV Flu Vaccine: CI, Precaution, SE,

A
  • Contraindications
    • Egg allergy/Vaccine Component
    • Moderate or severe illness
  • Precaution
    • GBS in 6 wks
  • SE
    • Site irriation
    • Fever, malasie (rare)
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8
Q

LIAV: Name, Target population, SE

A
  • FluMist (quadrivalent this year)
  • 2-49 yo; high risk populations
  • SE: headache, nasal congestion, sore throat
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9
Q

LAIV: CI

A
  • Severe allergic rxn egg/vaccine
  • Moderate/severe illness
  • <2 yo or >50, immunocompromised, pregant
  • Children <5 with wheezing
  • Children on long term aspirin
  • Current nasal congestion
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10
Q

LAIV: Precaution, Concurrent Admin

A
  • Precaution
    • GBS in 6 wks
    • Avoid severely immunocompromides for 7 days
  • Concurrent Admins
    • Same day or 4 wks
    • TB test >4 wk after live
    • LAIV not given until 48 hours after antiviral therapy stopped
    • If antiviral in 2 wks of vaccine, redose
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11
Q

LAIV: Admin

A
  • 1/2 sprayer into each nostril. Sneezing afterwards still confers immunity
  • Expiration date
  • Remove rubber
  • Keep stopper
  • Rapid admin
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12
Q

RIV: Advantage/Disadvantage

A
  • Advantage:
    • Fast production in pandemics
    • Not depend on egg
  • Disadvantage:
    • Narrow age (18-49)
    • Shorter shelf life (16 wk expire from production date)
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13
Q

Shingles: Name, Administartion, Concurrent Admin, Target population/schedul

A
  • Zostavax
  • Live Vaccine
  • Administer SubQ
    • Decreased effectiveness if given with PPSV23, but still give
    • Adminster other live vaccine 4 wk apart
    • Perform TB testing >4 wks
  • Population
    • 1 dose at >60
    • FDA now approve >50
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14
Q

Shingles: SE

A
  • Local reaciton
  • No fever/serious rxn
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15
Q

Shingles: Precautions

A
  • Current treatment with anti-viral against herpes (acyclovir)
  • Avoid antivirral therapy a day before and 14 days after
  • Cover any rash
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16
Q

Shingles: Contraindication/Storage

A
  • Immunosuprresion
  • Pregnancy (>4wk)
  • Anaphylaxis to vaccine
  • Moderate/severe illness
  • Storage
    • Freezer
    • Dilutent at room temp or fridge
    • Discard in not used within 30 minutes of reconstitution
17
Q

Shingles Additional Information

A
  • Only reduces occurrence of shingles by 50%
  • Boosting not recommended
  • Proper age range
18
Q

Pneumonia: Who is at most risk

A
  • Age 65 or older
  • Diabetes Mellitus
  • Cancer
  • Cigarette smoking
19
Q

Pneumococcal Polysaccharide Vaccine: Name and Example. Who not effective in. What it is for

A
  • PPSV23 or Pneumovax
  • Capsular Material
  • 85-90% cases
  • Not effective in <2 yo
  • NOT prevent pneumonia but prevent further complications
20
Q

PPSV: Concurrent Adminster, what is type

A
  • Potential for decreased shingles
  • NOT changed recommendation
  • Inactivated bacteria
21
Q

PPSV: Schedule/Revaccination

A
  • Schedule:
    • Adults 65 or older
    • >2 if risks like pulmonary, asplenia, renal failure, immunocompromised
    • >19 if asthma/cigs
  • Revaccination:
    • Routinely not recommended
    • Recommended for those >2 at risk of infection
    • >65 if recieved first dose before 65
    • 5 years after the first dose
22
Q

Pneumonia conjugate vaccine: Name, type, people

A
  • PCV13 or Prevnar 13
  • Capsular material
  • Covalently linked to a nontoxic protein
  • Protein helps children regonition
  • New recommendtation in adults
  • Type: inactivated
23
Q

PCV: Schedule

A
  • Children at 2, 4, 6, 12-15 months
  • Childern who recieved PPSV23 previously also should recieve the recommended PCV13
24
Q

PCV: Side Effects, CI

A
  • SE:
    • Local reaction
    • Fever, myalgia
  • CI:
    • Anaphylaxis to vaccine component
    • Moderate or severe illness
25
Q

Tdap/Td/DTaP/DT: What the letters mean, who do you give what, concurrent administer

A
  • diptheria and tetanus toxoids (lowercase=reduced toxoid)
  • Acceullar pertussis: inactivated bacteria
  • Young=All caps
  • Older=all lower cases except T
  • Concurretn Administer:
    • No restriction
26
Q

DTaP

A

Daptacel, Infanrix, Tripedia

27
Q

Tdap

A

Adacel, Boostrix

28
Q

Td

A

Tenivac (Decavac being replaced by Tenivac)

29
Q

DTap Schedule

A
  • 2, 4, 6, 15-18 months
  • Completed with same vaccine if possible
30
Q

Boosters of Tdap/Td/DTaP/DT schedule

A
  • DTaP: 4-6 yo prior to school entry
  • Tdap: 11-12 yo
  • Td every 10 years or Tdap if never had
31
Q

Those who haven’t had Tdap yet:

A
  • Adolescents: 11-12 yo
  • Adults: 19-64 yo
  • Adults 65 yo with contact with infant less than 1 year old
    • Tdap instead of Td
  • Pregnancy after 20 weeks
    • Tdap with EVERY pregnancy
  • Healthcare professionals
32
Q

Tdap/Td/DTaP/DT: SE, precautions

A
  • SE:
    • Local reaction, Fever
  • Precautions:
    • Symptoms in 2 days
      • Collapse
      • 105 fever
      • Inconsolable crying for 3 hours
    • Convulsions or seizures within 3 days
    • Epilepsy
    • Arthus type rxn following prior dose
    • GBS in 6 wks
33
Q

Tdap/Td/DTaP/DT: CI

A
  • Severe allergic rxn
  • Moderate or severe acute illness
  • Enecephalophy not attributate to other causes within 7 days administration or previous dose
34
Q

Travel Vaccinations: Type

A
  • Yellow Fever, Typhoid, Japanese Encephalitis
  • CDC website for country specific recommendations

Pharm 586 (5 decks)

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