mckee ch 29 lymphomas

Question 1

poikiloderma type of mycosis fungoids

Answer 1

poikiloderma atrophicans erythroderma (large plaque parapsoriasis

Question 2

clinical staging of MF depends on 3 factors

Answer 2

1) extent of the disease
2) presence of nodules
3) presence of erythroderma

Question 3

staging parameters of MF (4)

Answer 3

1) extent and nature of the skin lesions
2) presence and extent of nodal involvement
3) visceral involvement
4) presence and extent of peripheral nlood involvement

Question 4

4 blood parameters that tells poor prognosis

Answer 4

1) lactate dehydrogenase (lDH)
2) eSR erythrocyte sedimentation rate
3) soluble IL-2
4) blood eosinophilia

Question 5

describe T1

Answer 5

patch or plaque type MF with less than 10 percent involvement

Question 6

prognosis of T1

Answer 6

same with normal

Question 7

describe T2

Answer 7

patch or plaque with >10% involvement

Question 8

survival rate and percent regression of T2

Answer 8

10-12 year survival

25% progression

Question 9

what is T3 and T4

Answer 9

T3- tumor presence

T4 - erythroderma

Question 10

survival of T3 and t4

Answer 10

4-5 yrs

Question 11

survival rate of visceral involvement

Answer 11

1-2 yrs

Question 12

which Is more important in the prognosis? the size of LN or the extent of the disease

Answer 12

the extent

Question 13

major cause of death in MF

Answer 13

infection

Question 14

6 major etiologic agents for infection in MF

Answer 14

1) staphylococcus aureus
2) enterobacteriaceae
3) pseudomonas aeruginosa
4) beta hemolytic streptococcus
5) herpes simplex
6) varicella