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SBL Exam 2 > McGowan CIS > Flashcards

McGowan CIS Flashcards

1
Q

positive ds-DNA and anti-Smith Ab

A

SLE

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2
Q

anti-Histone Ab

A

drug-induced SLE

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3
Q

lip bx, anti-Ro/La

A

Sjogren syndrome

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4
Q

anti-centromere Ab, centromere pattern AMA

A

limited SSc

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5
Q

CREST syndrome

A

limited SSc

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6
Q

localized fibrosis, usually seen in kids

A

localized SSc

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7
Q

scaly/plaque lesions

A

discoid SLE

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8
Q

libman-sacks endocarditis (non-infective)

A

SLE or antiphospholipid Ab synd

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9
Q

esophageal adenocarcinoma

A

diffuse/limited SSC

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10
Q

gastric antral vascular ectasia

A

(GAVE synd aka watermelon stomach)

- diffuse SSc

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11
Q

pulmonary artery HTN

A

limited SSC

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12
Q

oral candidiasis

A

Sjogren

- due to sicca sx

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13
Q

NHL MATLoma

A

sjogren

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14
Q

jaw claudication

  • amarosis fugax
  • elevated ESR
A

GCA

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15
Q

temporal arteritis

A

GCA

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16
Q

polymyalgia rheumatica

A

GCA

- not true weakness, is feeling of weakness caused by severe pain

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17
Q

primary raynauds syndrome

A

SLE

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18
Q

Hep B infection

A

PAN

  • medium vessel
  • more common in men
  • NO lung involvement
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19
Q

DVT

A

SLE, antiphospholipid Ab synd, Behcet

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20
Q

temporal A bx shows granuloma/multi nucleated giant cells

A

PMR

- muscle bx is NORMAL

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21
Q

ds-DNA

A

SLE

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22
Q

anti-Smith

A

SLE

- does NOT correlate with disease activity (so not specific)

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23
Q

centromere Ab

A

CREST syndrome (limited SSc)

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24
Q

anti-Scl 70

A

diffuse SSc

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25
Q

(+) DNA topoisomerase I, (+) RNA polymerase III Abs

A

diffuse SSc

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26
Q

abnormal DRVVT

A

dilute Russel Viper venom test

- SLE and antiphospholipid Ab syn

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27
Q

Histone Ab

A

drug-induced SLE

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28
Q

cotton wool spots in retina

A

antiphospholipid Ab synd

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29
Q

cyclic citrullinated peptide (CCP)

A

rheumatoid arthritis

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30
Q

hydroxychoroquine and warfarin

A

tx for SLE w/ DVT

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31
Q

IVIG and high dose aspirin (ASA)

A

Kawasaki

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32
Q

amlodipine

A

CCB good for Raynaud’s

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33
Q

interstitial lung disease

A

diffuse SSc (lung dz main COD)

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34
Q

atherosclerosis

A

SLE (they have accelerated atherosclerosis)

  • cardio-renal problems cause mortality in early disease
  • can also have intestinal angina, neuro/psych, or seizure disorders, but not likely cause of death
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35
Q

pulmonary artery HTN

A

limited SSc

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36
Q

libman-sachs endocarditis

A

antiphospholipid Ab syndrome

- sterile nodules, NOT bacterial

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37
Q

mitral regurgitation (holocystolic murmur)

A

antiphospholipid ab synd

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38
Q

pericardial effusion, substernal chest pain

- positional angina (better when leaning forward)

A

SLE pericarditis

- steroids improve!

39
Q

group A strep

- mitral STENOSIS

A

rheumatic heart disease

40
Q

bacterial emboli

- positive blood cultures

A

infectious endocarditis

41
Q

irregular HR

- arterial thrombus on echo

A

persistent atrial fibrillation

42
Q

anti ds-DNA ab

A

SLE (highly specific!)

43
Q

elevated creatinine kinase

A

inflammatory myopathy

44
Q

IgA deposition

A

Henoch-Schlonen Purpura (HSP)

45
Q

heliotrope rash

A

dermatomyositis

46
Q

who needs a flu and pneumonia vaccine regularly?

A

SLE

47
Q

order a PFT

A

diffuse SSc

48
Q

schedule an echocardiogram

A

PAN and limited SSc

49
Q

schedule EGD

A

limited and diffuse SSc

- GAVE syndrome -> adenocarcinoma of esophagus

50
Q

strawberry tongue

A

Kawasaki, strep pharyngitis, scarlet fever

51
Q

purple-red rash on eyelids

A

heliotrope rash -> DM

52
Q

proximal muscle weakness

A

DM or PM

53
Q

dilation of small vessels causing focal red lesions

A

telangiectasias -> CREST -> limited SSc

- check anti-centromere Ab!

54
Q

parotid gland enlargement

A

sjogren and mumps

55
Q

type III hypersensitivity rxn

A

SLE (immune complex = C3 and C4 are low)

56
Q

Hep B infection

A

PAN

57
Q

should be screened for cervical cancer

A

DM

58
Q

photosensitivity

A

SLE

59
Q

esophageal dysmotility

A

CREST -> limited SSc

60
Q

pericarditis

A

SLE

61
Q

MALToma

A

sjogren

62
Q

temporal arteritis

- jaw claudication, headache, vision disturbances

A

PMR

63
Q

pulmonary artery HTN

A

limited SSc

64
Q

asthma

A

eosinophilic granulomatous polyangiitis

65
Q

interstitial lung disease

- DRY crackles at base of the lung

A

diffuse SSc

66
Q

WET crackles

A

CHF

67
Q
  • positive anti-CN1A Abs
  • rimmed vacuoles
  • mildly elevated CK
A

inclusion body myositis (IBM)

- weakness in fingers or quadriceps

68
Q

“pulseless disease”

A

takayasu arteritis

  • uncontrolled HTN
  • collateral vessel dvlpment -> ischemic limb is rare
69
Q
  • copper wiring retinal infarctions

- narrowing of renal arteries

A

takayasu arteritis

70
Q

coronary artery aneurysm

A

kawasaki (late complication)

71
Q

pulmonary embolus

A

SLE, antiphospholipid Ab synd, Behcet

72
Q

MI

A

kawasaki, SLE, atherosclerosis

73
Q

IgA deposition

A

Henoch-Scheonlein purpura (HSP)

74
Q

anti-GBM Abs

A

goodpasture syndrome

- renal and pulmonary involvement

75
Q

mouth/genital sores

- HLA-B51

A

Behcet syndrome

76
Q

nasal/sinus issues, lungs

  • granulomas
  • urine shows protein, microscopic blood, granular casts
A

granulomatosis with polyangiitis (GPA)

77
Q

start corticosteroids before biopsy to prevent biopsy

A

temporal arteritis -> PMR or GCA

  • jaw claudication
  • persistent headache
  • vission problems
  • elevated ESR
78
Q

right heart catheterization

A

limited SSc (pulmonary HTN)

79
Q

mammogram

A

DM -> look for occult malignancy

80
Q

red or violet-colored bumps that occur on the top part of the hand, specifically the knuckle

A

gottron’s papules -> DM

81
Q

areas of hypo/hyperpigmentation, telangiectasia and atrophy

A

poikiloderma -> DM

82
Q

rimmed vacuoles and inclusion bodies

A

inclusion body myositis

83
Q
  • muscle biopsy normal
  • elevated ESR
  • weakness from pain (not true weakness)
A

polymyalgia rheumatica -> GCA

84
Q

asthma + vasculitis (palpable purpura) + ANCA-ab/granuloma

A

eosinophilic granulomatosis with polyangiitis

- aka Churg-Strauss syndrome

85
Q

primary biliary cirrhosis

A

diffuse SSc

86
Q

PAN spares which organ system?

A

lungs

87
Q

most likely cause of mortality in late kawasaki?

A

coronary artery aneurysm

88
Q

IVIG treatment

A

kawasaki

89
Q

pulmonary embolus

A

Bechet or APS

90
Q

CHF

A

PAN

91
Q

aortic rupture

A

takayasu arteritis (large vessel)

92
Q

erosive sinus disease (saddle nose)

  • upper/lower respiratory tract issues (granulomas)
  • renal and skin manifestations
A

GPA

93
Q

positive PR3-ANCA

A

GPA

94
Q

smoking

A

Buergers

  • young men
  • painful necrotic ulcers on extremities

SBL Exam 2 (13 decks)

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