McGowan CIS Flashcards
1
Q
positive ds-DNA and anti-Smith Ab
A
SLE
2
Q
anti-Histone Ab
A
drug-induced SLE
3
Q
lip bx, anti-Ro/La
A
Sjogren syndrome
4
Q
anti-centromere Ab, centromere pattern AMA
A
limited SSc
5
Q
CREST syndrome
A
limited SSc
6
Q
localized fibrosis, usually seen in kids
A
localized SSc
7
Q
scaly/plaque lesions
A
discoid SLE
8
Q
libman-sacks endocarditis (non-infective)
A
SLE or antiphospholipid Ab synd
9
Q
esophageal adenocarcinoma
A
diffuse/limited SSC
10
Q
gastric antral vascular ectasia
A
(GAVE synd aka watermelon stomach)
- diffuse SSc
11
Q
pulmonary artery HTN
A
limited SSC
12
Q
oral candidiasis
A
Sjogren
- due to sicca sx
13
Q
NHL MATLoma
A
sjogren
14
Q
jaw claudication
- amarosis fugax
- elevated ESR
A
GCA
15
Q
temporal arteritis
A
GCA
16
Q
polymyalgia rheumatica
A
GCA
- not true weakness, is feeling of weakness caused by severe pain
17
Q
primary raynauds syndrome
A
SLE
18
Q
Hep B infection
A
PAN
- medium vessel
- more common in men
- NO lung involvement
19
Q
DVT
A
SLE, antiphospholipid Ab synd, Behcet
20
Q
temporal A bx shows granuloma/multi nucleated giant cells
A
PMR
- muscle bx is NORMAL
21
Q
ds-DNA
A
SLE
22
Q
anti-Smith
A
SLE
- does NOT correlate with disease activity (so not specific)
23
Q
centromere Ab
A
CREST syndrome (limited SSc)
24
Q
anti-Scl 70
A
diffuse SSc
25
(+) DNA topoisomerase I, (+) RNA polymerase III Abs
diffuse SSc
26
abnormal DRVVT
dilute Russel Viper venom test
| - SLE and antiphospholipid Ab syn
27
Histone Ab
drug-induced SLE
28
cotton wool spots in retina
antiphospholipid Ab synd
29
cyclic citrullinated peptide (CCP)
rheumatoid arthritis
30
hydroxychoroquine and warfarin
tx for SLE w/ DVT
31
IVIG and high dose aspirin (ASA)
Kawasaki
32
amlodipine
CCB good for Raynaud's
33
interstitial lung disease
diffuse SSc (lung dz main COD)
34
atherosclerosis
SLE (they have accelerated atherosclerosis)
- cardio-renal problems cause mortality in early disease
- can also have intestinal angina, neuro/psych, or seizure disorders, but not likely cause of death
35
pulmonary artery HTN
limited SSc
36
libman-sachs endocarditis
antiphospholipid Ab syndrome
| - sterile nodules, NOT bacterial
37
mitral regurgitation (holocystolic murmur)
antiphospholipid ab synd
38
pericardial effusion, substernal chest pain
| - positional angina (better when leaning forward)
SLE pericarditis
| - steroids improve!
39
group A strep
| - mitral STENOSIS
rheumatic heart disease
40
bacterial emboli
| - positive blood cultures
infectious endocarditis
41
irregular HR
| - arterial thrombus on echo
persistent atrial fibrillation
42
anti ds-DNA ab
SLE (highly specific!)
43
elevated creatinine kinase
inflammatory myopathy
44
IgA deposition
Henoch-Schlonen Purpura (HSP)
45
heliotrope rash
dermatomyositis
46
who needs a flu and pneumonia vaccine regularly?
SLE
47
order a PFT
diffuse SSc
48
schedule an echocardiogram
PAN and limited SSc
49
schedule EGD
limited and diffuse SSc
| - GAVE syndrome -> adenocarcinoma of esophagus
50
strawberry tongue
Kawasaki, strep pharyngitis, scarlet fever
51
purple-red rash on eyelids
heliotrope rash -> DM
52
proximal muscle weakness
DM or PM
53
dilation of small vessels causing focal red lesions
telangiectasias -> CREST -> limited SSc
| - check anti-centromere Ab!
54
parotid gland enlargement
sjogren and mumps
55
type III hypersensitivity rxn
SLE (immune complex = C3 and C4 are low)
56
Hep B infection
PAN
57
should be screened for cervical cancer
DM
58
photosensitivity
SLE
59
esophageal dysmotility
CREST -> limited SSc
60
pericarditis
SLE
61
MALToma
sjogren
62
temporal arteritis
| - jaw claudication, headache, vision disturbances
PMR
63
pulmonary artery HTN
limited SSc
64
asthma
eosinophilic granulomatous polyangiitis
65
interstitial lung disease
| - DRY crackles at base of the lung
diffuse SSc
66
WET crackles
CHF
67
- positive anti-CN1A Abs
- rimmed vacuoles
- mildly elevated CK
inclusion body myositis (IBM)
| - weakness in fingers or quadriceps
68
"pulseless disease"
takayasu arteritis
- uncontrolled HTN
- collateral vessel dvlpment -> ischemic limb is rare
69
- copper wiring retinal infarctions
| - narrowing of renal arteries
takayasu arteritis
70
coronary artery aneurysm
kawasaki (late complication)
71
pulmonary embolus
SLE, antiphospholipid Ab synd, Behcet
72
MI
kawasaki, SLE, atherosclerosis
73
IgA deposition
Henoch-Scheonlein purpura (HSP)
74
anti-GBM Abs
goodpasture syndrome
| - renal and pulmonary involvement
75
mouth/genital sores
| - HLA-B51
Behcet syndrome
76
nasal/sinus issues, lungs
- granulomas
- urine shows protein, microscopic blood, granular casts
granulomatosis with polyangiitis (GPA)
77
start corticosteroids before biopsy to prevent biopsy
temporal arteritis -> PMR or GCA
- jaw claudication
- persistent headache
- vission problems
- elevated ESR
78
right heart catheterization
limited SSc (pulmonary HTN)
79
mammogram
DM -> look for occult malignancy
80
red or violet-colored bumps that occur on the top part of the hand, specifically the knuckle
gottron's papules -> DM
81
areas of hypo/hyperpigmentation, telangiectasia and atrophy
poikiloderma -> DM
82
rimmed vacuoles and inclusion bodies
inclusion body myositis
83
- muscle biopsy normal
- elevated ESR
- weakness from pain (not true weakness)
polymyalgia rheumatica -> GCA
84
asthma + vasculitis (palpable purpura) + ANCA-ab/granuloma
eosinophilic granulomatosis with polyangiitis
| - aka Churg-Strauss syndrome
85
primary biliary cirrhosis
diffuse SSc
86
PAN spares which organ system?
lungs
87
most likely cause of mortality in late kawasaki?
coronary artery aneurysm
88
IVIG treatment
kawasaki
89
pulmonary embolus
Bechet or APS
90
CHF
PAN
91
aortic rupture
takayasu arteritis (large vessel)
92
erosive sinus disease (saddle nose)
- upper/lower respiratory tract issues (granulomas)
- renal and skin manifestations
GPA
93
positive PR3-ANCA
GPA
94
smoking
Buergers
- young men
- painful necrotic ulcers on extremities
