Matson Flashcards
Primary role of immune system
Discriminate self vs non self
Allergies
Overrecation of immune system to a normally harmless substance
Sensitization Stage (3)
Antigen (allergen) enters the body
Plasma cells produce IgE
I’ve attaches to mast cell (found throughout tssiue )
Subsequent Response
Antigen enters the body, attaches IgE
Attachment to IgE triggers the release of chemical mediators
Chemical Mediators (define)
Responsible FOR S/S
Of allergies
Chemical mediators : intravascular compartment
Rt to blood vessel Anaphylaxis
Chemical mediators :Skin (HRF)
Erythema
- Utacaria (hives)= pink raised edematous itchy areas
- Atopic dermatitis = interstitial edema
- Wheat-flare reaction (large welts) = pale wheal edemtous fluid surrounded by a red flare from hypermia ( mosquito bite)
- Angioedema (swelling of lips, eyes)
Chemical mediators :Respiratory
Rhintins = hay fever nasal discharge, sneezing, tearing AIREAY OBSTRCUSTION
Asthma - thick sputum
Chemical mediators : GI
N/V/D
CRAMPING
Most common chemi Al mediators
Histamine
Seriontin
Leukotrienes
Prostgoadins
Modes of entry
Inhalation
Ingestion
Injection
Skin contact
Drug Therapy for allergies
Anhistamaines( Benadryl, Claritin, Zyrtec)
Antipruritic drugs (calamine lotion)
Corticosteroids (to decrease inflammation)
Antihistamines (benadryl, claritin, zyrtec)
( mechnaism , side effects, nursing actions)
- benadryl = blocks histamine release , relieve acute allergic symptoms
S/E= cross BBB causes sedation + nervousness, restlessness. Anticholngeric reaction( can’t see, can’t shit, can’t spit)
Nursing Actions: warn pt that operating machinery, report applications, change in HR, change in bowel. NO ETOH
- Zyrtec+ Clartin= same above
S/E= limited brain receptors causing minimal sedation and effects
Nursing Actions= teach pt about cost and less side effects
- Steroid = inhibits response of rhinits, decreasing muscousl inflammation
S/E= mild irritation, mucousal nose drying, nosebleeds, fungal infections
Nursing Actions= adherence important. Teach pt to use regular basis not PRN. Have pt clear nsal passages before use. Stop if nasal infection
Calamine
Provide relief from itching, skin protected
Growth and Developmental Consderations
- Infants: usually a skin reaction, often food related
- Child: allergic rhinitis is most common
- Adolescents: new environments, trying new foods = new allergies
- Middle adulthood: less likely to develop new allergies, but possible
- Elderly: may not know they are allergic to newer antibiotics b/c they haven’t taken them