Maternity Ch. 3 Flashcards
Teratogens
drugs, viruses, infections, or other exposures that have the potential to cause embryonic/fetal developmental abnormality
***Environmental toxins (ex: where they work like use of chemicals)
How is the degree of malformations from teratogens based on?
Based on length of exposure, amount of exposure, and when it occurs during human development
Effects of tegretol (cabamazepine)
Increased risk of:
Neural tube defects
Craniofacial defects, including cleft lip and palate
Intrauterine growth restriction
Effects of toxoplasmosis
Increased risk of:
Fetal demise
Blindness
Mental retardation
Where can you contract toxoplamosis?
Due to cats ( don’t change cat litter)
Undercooked beef/lamb
Embryo
Developing human from time of implantation through 8 weeks of gestation
Organogenesis
Formation and development of body organs
-happens at 8 weeks
Primary germ layers ?
What do they do?
Ectoderm, Mesoderm, and endoderm
Form the organs, tissues, and body structures of the developing human
When does the heart form?
3rd week of gestation and begins to beat and circulate blood during the 4th week
Fetus
week 9 to birth
How is the placenta formed?
from both fetal and maternal tissue
FXNs of placenta
- Metabolic and gas exchange
- Hormone production
Placenta: Metabolic gas exchnage
In the placenta, fetal waste products and CO2 are transferred from the fetal blood into the maternal blood sinuses by diffusion. Nutrients such as glucose and amino acids and O2 are transferred from the maternal blood sinuses to the fetal blood through the mechanisms of diffuse and active transport.
***Does not create nutrients but allows for exchange
Hormones produced in the placenta
- Progesterone
- Estrogen
- hCG
- hPL
Progesterone fxn
Progesterone facilitates implantation and decreases uterine contractility