Maternal & Newborn Lecture 10 Flashcards
Physiologic, Anatomic & Behavioral Adaptations of the Newborn
- Physiological, Anatomical, and Behavioral Adaptations of the Newborn:
- Establishing and maintaining respirations
- Undergoing circulatory changes
- Regulating thermoregulation
- Regulating weight and blood glucose levels
- Ingesting, retaining, and digesting nutrients (note: they no longer have their umbilical cord)
- Developing arousal and sleep patterns (babies in the uterus are less active during the day and more active at night, which is why kick counts are encouraged during pregnancy; this pattern persists after birth)
- Establishing a relationship with caregivers and the environment from day one; they recognize their mother’s voice (also people around her), smell, and energy
- Processing multiple stimuli; transitioning from a stable, warm environment in the womb to a world with a lot of sensory stimulation, which can also help initiate the respiratory process
Respiratory System:Function in Fetus
- Fetal Lung Function:
- During fetal development, the lungs play a limited role and are not primarily used for gas exchange.
- Gas exchange occurs through the placenta, which acts as the respiratory organ for the fetus.
- Fetal Lung Fluid: (similar to amniotic but not exactly the same)
- The lungs of the fetus are filled with a fluid similar to amniotic fluid, but it is a filtered version and not actively inhaled.
- This fluid must be removed from the lungs after delivery to allow air to fill them.
- Removal of Fetal Lung Fluid:
- Fetal lung fluid is removed through the birth process and reabsorption into the body. (it’s sent somewhere else in the body: lymphatic system to be expelled)
- Some of the fluid is reabsorbed into the fetal body, while the remaining portion is typically expelled during the birthing process.
- Gas Exchange and Cardiovascular Function in Fetal Structures:
- Fetal gas exchange is closely connected to the cardiovascular system, which includes temporary passages or vessels called shunts.
- These shunts are essential during fetal development but must close once the baby is born.
- The path of blood circulation in the baby’s body undergoes significant changes immediately after birth.
- The respiratory system: The respiratory system takes a back seat before the baby is born and is less involved compared to when the baby is born.
- Initiation of breathing: The exact trigger for starting respirations is not fully understood. Several theoretical ideas exist, and most of them are generally correct. Multiple stimuli are involved.
- Various variables that initiate the respiratory process include:
- Chemical factors
- Mechanical factors
- Thermal factors
- Sensory factors
Chemical Resp
- Birth process and anoxia: The birth process involves a relative period of anoxia, meaning there is no oxygen and hypercapnia (high CO2) present. The low O2 and high CO2 levels act as chemical signals that stimulate the body’s sympathetic nervous system to initiate the respiratory drive.
- Umbilical cord clamping: When the umbilical cord is clamped, it stops the flow of blood from the placenta to the baby. The baby’s lungs gradually start taking over the oxygen supply as they begin to breathe, and the circulatory system adapts accordingly.
- Activation of chemoreceptors: Chemoreceptors in the aorta and carotid arteries are activated in response to hypoxia (low oxygen) and hypercapnia (high CO2).
- Prostaglandin level drop: (no prostaglandins=no dilatation. No dilatation = contriction of the smooth muscle surrounding the pulmonary artery. This constriction of smooth muscles and therefore of the pulmonary artery sends blood to the lungs) After cord clamping, prostaglandin levels decrease because the cord is cut. Prostaglandins were responsible for maintaining cardiac shunts. Once they decrease, these shunts start forming more ligament-like tissue. (Prostaglandins play a role in maintaining the patency
The transformation of a fetal circulatory shunt into a ligament occurs as part of the normal postnatal development process. Shunts are temporary structures in the fetal circulatory system that serve specific functions before birth. After birth, when these functions are no longer needed, these shunts gradually close and are replaced by ligamentous structures. Here’s how this process occurs:
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Fetal Shunt Function: Before birth, certain shunts in the fetal heart are essential for redirecting blood flow to bypass non-functional fetal organs. The two most prominent shunts are the ductus arteriosus and the foramen ovale.
- Ductus Arteriosus: This shunt connects the pulmonary artery to the aorta, allowing oxygen-poor blood from the pulmonary artery to bypass the non-functioning fetal lungs and enter the systemic circulation.
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Foramen Ovale: This is an opening between the two atria (upper chambers) of the fetal heart, permitting blood to bypass the right ventricle and flow directly from the right atrium to the left atrium, again helping to bypass the non-functional fetal lungs.
Ductus Arteriosus: Oxygenated blood from the placenta is carried to the fetal liver via the umbilical vein.
Bypassing the Liver: In the fetal liver, only a portion of the blood flows through the hepatic circulation for metabolic processes. The ductus venosus is a shunt or vessel that diverts a significant portion of the oxygenated blood from the umbilical vein, bypassing the liver.
- Transition at Birth: After a baby is born and takes its first breath, there is a significant increase in oxygen levels in the bloodstream. This increase in oxygen triggers several changes in the circulatory system, including the closure of these shunts.
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Closure Process: The closure of the ductus arteriosus and foramen ovale involves several steps:
- Decrease in Prostaglandins: As the baby breathes and oxygen levels rise, prostaglandin levels, particularly prostaglandin E2 (PGE2), decrease. Prostaglandins help keep the ductus arteriosus open, so their decrease signals its closure.
- Constriction of Smooth Muscle: With the decrease in prostaglandins and the increase in oxygen, the smooth muscle cells in the walls of the ductus arteriosus contract. This gradually narrows the vessel and ultimately closes it off.
- Fibrous Tissue Formation: Over time (hours to days), the closed ductus arteriosus undergoes a process of fibrous tissue formation. It becomes gradually occluded by connective tissue, transforming it into a fibrous cord called the “ligamentum arteriosum.”
- Foramen Ovale Closure: Similarly, the foramen ovale closes as the pressure in the left atrium exceeds that in the right atrium due to increased blood flow to the lungs. Over time, the two atrial septa (walls) grow together, sealing the foramen ovale, and it becomes the “fossa ovalis.”
- Ligament Formation: The resulting fibrous structures, the ligamentum arteriosum and the fossa ovalis, are essentially remnants of the fetal shunts. They serve no functional purpose in postnatal life but persist as anatomical landmarks.
The closure of these shunts and their transformation into ligaments are essential steps in the adaptation of the circulatory system from fetal to neonatal circulation. This process ensures that oxygenated blood is properly directed through the fully functional lungs after birth, meeting the oxygen needs of the newborn.
Mechanical resp
- Vaginal birth and lung fluid expulsion: Babies born through the vagina experience significant pressure (mechanical pressure exerted on the baby’s chest and lungs during the process of passing through the birth canal ), expelling a substantial amount of fetal lung fluid. Crying plays a role in this process, increasing thoracic pressure.
- Mechanical factors:
- Increased thoracic pressure
- Lung expansion through crying
- Expulsion/absorption of fetal lung fluid (Lymphatic Clearance)
- Thermal factors: Cold stimulation helps stimulate the sympathetic nervous system and respiratory drive.
- Sensory factors:
- Handling and tactile stimulation during birth
- “Warm dry stem” when placing the baby on the mother’s chest, followed by wrapping the baby in a warm blanket for stimulation.
- Tradition of stimulating the baby, akin to the traditional practice of the doctor gently slapping the baby to encourage breathing.
- Suctioning, especially for babies born via C-section, where significant fluid may need to be suctioned, sometimes requiring deep suctioning.
Factors in Neonatal Respiration
- Factors determining newborn’s breathing after birth:
- Vaginal vs. C-Section delivery (The method of delivery can affect a newborn’s initial respiratory effort. Babies born vaginally often experience the natural process of clearing lung fluids and mucus during their passage through the birth canal, which can help initiate breathing. In contrast, babies born via C-section may not have this exposure and might require additional assistance to start breathing.)
- Surfactant: A lipoprotein preventing alveolar collapse
- Preterm babies have reduced surfactant, affecting their breathing
- Surfactant production typically starts around week 24, varying among fetuses
- Difficulty predicting breathing outcomes for babies born between 24 to 28 weeks
- For preterm birth risk, administer two shots of betamethasone (steroid) 24 hours apart to promote lung maturation
- Production of surfactant prevents alveolar collapse
- Age is a factor due to the lack of surfactant
- Surfactant production usually complete by 35 weeks
- Meconium: Can lead to aspiration; it’s the earliest stool, appearing black and tar-like, challenging to suction, and attracts pathogens
- Anatomical defects, like congenital heart issues or diaphragmatic hernia, can impact breathing; often detectable before birth but can still be unexpected.
Respiratory SystemNormal Newborn Respirations
- Normal rate: 30-60 breaths per minute
- Breathing is shallow and irregular
- Rales are common within the first hour
- Abdominal breathers
- Nose breathers, also known as obligate nose breathers; they are required to breathe through their nose but can breathe through their mouth if necessary
- Short period of apnea < 10 seconds is considered “normal”
- Anything longer than 10 seconds requires a full workup (Anything longer than that, they will need a full workup. This is why we listen for a full minute. Because if we listen for 15 sec and we get 2 breaths then we get a resp rate of 8, then it’s probably not accurate. Shallow and irregular, if you just watch for the rise and fall you might miss it, this is why you have to auscultate.)
- Listening for a full minute is essential for accuracy
- Rales can also be common in the first hour
Respiratory SystemAbnormal Newborn Respirations
- Grunting: A sound made by a baby working harder to open the glottis
- Flaring: The use of accessory costal and subcostal muscles to breathe
- Retractions: Intracostal and subcostal retractions indicate high intrathoracic pressure
- Bradypnea: Slow breathing
- Tachypnea: Rapid breathing
- Abnormal breath sounds: Crackles, rhonchi, wheezes, expiratory grunt
- Respiratory distress syndrome (RDS) indicators: Grunting, Flaring, Retracting
- Cyanosis and mottling: Color changes in extremities due to increased respiratory effort
- Acrocyanosis: Normal color change in the first few hours, monitored for resolution
- Central cyanosis: Baby becomes entirely blue, a concerning sign
- Low pulse oximetry value: Used only when the baby shows signs of respiratory distress
CARDIOVASCULAR CHANGES
- Shunts close at birth
- Pulmonary circulation established
- Normal heart rate (HR): 110-160 beats per minute
- Dysrhythmias are common, and any unusual heart sound should be reported (if you hear a weird heart sound tell somebody. Just because they are common it doesn’t mean that they are benign. Any baby with a murmur and any kind of audible dysrhythmia, skipped beat. We need to tell the doc that the baby needs an ECG and echo cardiogram. )
- Murmur or audible dysrhythmia requires an ECG and echocardiogram
- Initial increase in red blood cells (RBCs)
Cardiovascular System:Fetal Circulation
- Placenta: Site of gas and nutrient exchange
- Umbilical Cord:
- 1 vein (high O2) carrying oxygenated blood from placenta to fetus’s heart
- 2 arteries (low O2) carrying deoxygenated blood from fetus to placenta
- Umbilical vein delivers oxygen (O2) to the fetus
- Liver mostly bypassed, as filtration occurs in the placenta
- Ductus venosus (shunt 1) helps bypass the liver
- High O2 blood enters the inferior vena cava to the right atrium
- High O2 blood (majority) is shunted from the right atrium to the left atrium via the foramen ovale (shunt 2), avoiding pulmonary circulation
- High O2 blood proceeds from the left atrium to the left ventricle, then to the ascending aorta, and subsequently to various body parts to provide O2
- In contrast, low O2 blood bypasses the lungs via ductus arteriosus (shunt 3) and returns to the placenta through the descending aorta and umbilical arteries.
Cardiovascular System:
Changes After Delivery
- Umbilical Vein:
- Cord clamped: Changes resistance in the baby’s body.
- High resistance. It happens when we cut the cord very early. The body causes vascular resistance by the contraction of smooth muscles and then vessels to make sure that there is enough BP to reach the tissues in the body.
- Ductus Venosus: Not used after birth
- Foramen Ovale: Pressure on the left > right to close the foramen ovale
- Ductus Arteriosus
- Umbilical Artery:
- Even if the umbilical vessels are not clamped, they will eventually stop when the placenta detaches and they come in contact with the air. This because when the moms body senses that the placenta is not there it understands that there isn’t a baby to feed and therefore it stops working and supply baby with stuff.
- The circulation will cease whether the cord is clamped or not.
- Ductus arteriosus Contracts in response to increased oxygen (O2) and decreased prostaglandins. This is because usually the ductus arteriosus carries blood without o2 to the descending aorta then to the umbilical artery to send it to the placenta to get O2. Now that the baby’s lungs are working the blood that comes to the doctus arteriosus is rich in O2 and this is a signal that tells it that it’s no longer needed, so it starts closing.
Cardiovascular System:
Change in Blood Composition
- Fetal Hemoglobin:
- RBC size initially larger than an adult’s.
- RBCs have a greater affinity for oxygen (O2) than ours, making them better at binding to O2.
- After birth:
- RBC count increases.
- RBC cell size decreases.
- Newborn Blood Values:
- Hemoglobin: 16-18 g/dL
- Hematocrit: 46-68%
- Hemoglobin and hematocrit levels are higher after birth and then gradually decline.
- The destruction of RBCs leads to greater iron stores.
- Fetal hemoglobin and hematocrit are higher in newborns than in adults. A hemoglobin level of 18 and a hematocrit of 68, which would be problematic in adults, are normal for babies. Initially, babies have higher hemoglobin and hematocrit levels, which gradually decline over a couple of months.
- Fetal RBCs are initially larger than those of adults and have a greater affinity for oxygen (O2).
- After birth, there is an increase in the RBC count, but the size of individual RBCs decreases.
DELAYED CORD CLAMPINGNew ACOG/AAP guidelines
- It’s important to ensure that the baby is dry initially.
- In the past, the standard procedure after a baby’s birth was immediate cord clamping, cutting, and then releasing the baby. However, this practice has shifted towards evidence-based methods. The collection of stem cells from placentas for storage has become less favorable. Instead, the trend is toward delayed cord clamping, which has several benefits:
- Increases hemoglobin (Hgb) levels at birth.
- Improves iron stores in the baby’s body as more Hgb breaks down.
- Enhances transitional circulation in all babies, particularly benefiting preemies by reducing the need for blood transfusions. It is especially valuable for babies at risk of cerebral hemorrhage or GI system infections, such as necrotizing enterocolitis and intraventricular hemorrhage.
- It’s worth noting that sometimes, babies subjected to delayed cord clamping may receive more blood volume than they require, leading to a condition called Polycythemia. This can make the blood denser and cause respiratory distress due to increased difficulty in oxygen transport.
Assessment of NewbornTransition
- Apgar scoring is performed after 1 minute of birth because the baby is still adjusting. Various stimulations and interventions are carried out to assist the baby during this time. Another Apgar assessment is conducted after 5 minutes, and if the score is less than 7, an additional assessment is performed after 10 minutes.
- Inadequate perfusion can result from respiratory issues, cardiovascular problems, or a combination of both.
- During assessment, watch for signs of respiratory distress or compromised cardiac function.
- Additionally, assess for mottling (similar to bruising) and cyanosis as potential indicators of the baby’s health status.
MOTTLING OF SKIN
Stress
Respiratory
Cold
Sepsis
Acrocyanosis
Blue discoloration of extremities as blood preferentially circulates to organs during extrauterine transition. this is normal in the first 2h-
Perioral/Circumoral Cyanosis
- Perioral/Circumoral Cyanosis: This condition involves a bluish discoloration around the baby’s mouth. It is quite common within the first 24 hours of life and is often associated with Transient Tachypnea of the Newborn (TTN or TTNB). Perioral cyanosis in this context typically indicates that the baby is breathing a bit more rapidly than usual, but otherwise, everything else is normal. It’s worth noting that it can sometimes be confused with facial bruising, particularly when the baby is delivered rapidly by the mother.
- TTNB usually resolves within 24-48 hours.
- It’s important to be aware that facial bruising may be mistaken for perioral cyanosis in some cases.
Perioral Cyanosis
CENTRAL CYANOSIS
- A crying baby at birth is a positive sign, even if they appear bluish at times, because it indicates respiratory effort and oxygen intake.
- Hypoxemia: This is a late sign of distress and indicates low oxygen levels in the blood.
- Meconium Aspiration: A condition where the baby inhales meconium (the first stool) into the lungs, potentially causing pneumonia.
- PPHN (Persistent Pulmonary Hypertension of the Newborn “
Pulmonary circulation refers to the portion of the circulatory system that is responsible for the circulation of blood between the heart and the lungs”): This condition results from circulatory changes, such as shunts not closing properly, leading to abnormal lung pressure and improper lung expansion. Basically now baby is born so no blood with o2 from mom’s placenta. baby has to rely on it’s lungs to get o2, but the shunts don’t close after birth. this means that the blood without o2 is still bypassing the lungs to pick up o2. This bypassing including the lungs means less blood with o2 for the lung tissue. To compensate for the low o2 in the lung BV these BV constrict. This worsens the problem even more. - Cardiac dysfunction: Refers to issues with the baby’s heart function, which can be a cause of distress and affect their overall well-being.
Set up for Physiological Jaundice…
THERMOREGULATION
- Babies have immature regulation abilities, and it’s crucial to keep them warm because they can’t effectively maintain their other physiological processes when they are cold. Cold stress in a baby can lead to increased oxygen (O2) consumption, but the body can’t use it efficiently (Immature Respiratory System), causing the baby to burn its brown fat stores (found in the neck, upper chest, and spine) rapidly. This can lead to a drop in blood glucose levels, contributing to respiratory distress. The increased O2 demand, inefficient utilization, and efforts to maintain warmth can lead to decompensation in various ways.
- Shivering can occur when the baby’s blood sugar is too low, indicating hypoglycemia, which is a serious condition in newborns.
- Placing a baby on the mother’s body is ideal because the baby can sense the mother’s body temperature and regulate its own accordingly. This close contact and warmth also help regulate the baby’s respiratory rate. While this can also be done with other caregivers, it’s not quite the same as the mother’s body.
- Newborns have a thin layer of subcutaneous (SQ) fat, with blood vessels close to the surface of the skin. They also have a larger surface-to-body ratio compared to adults, which means they can lose heat more quickly.
- Cold stress in newborns can increase their need for oxygen (O2).
THERMOREGULATIONNewborn response to cold
Babies employ various mechanisms to warm themselves up when they are cold, including:
- Crying to generate energy: The physical act of crying can help generate heat by increasing a baby’s metabolic rate.
- Flexed position to retain heat: Babies often curl into a flexed position to conserve heat and minimize heat loss from their bodies. Less surface area means less exposure to environment = less heat loss.
- Increased muscle activity: Babies may increase their muscle activity, such as moving their limbs, to generate some heat.
- Acrocyanosis: This is a bluish discoloration of the extremities caused by reduced blood flow to the peripheral areas, helping to divert blood and conserve warmth for vital organs.
- Unstable blood glucose: Cold stress can lead to fluctuations in blood glucose levels, which can affect the baby’s metabolism and overall temperature regulation.
Additionally, non-shivering thermogenesis is an essential process in newborns for warming themselves. It involves an increase in metabolism, mainly through the burning of brown adipose tissue (brown fat). Brown fat is specialized for heat production and is crucial for helping babies maintain their body temperature in cold environments.
Check slide 29 must and 30
Brown
Adipose
Tissue (BAT)
Rapidly depleted by cold stress
Cold stress in infants
Cold stress in infants can have several physiological effects, including:
- Increased Oxygen Consumption: When exposed to cold, infants experience an increase in oxygen consumption as their bodies work to generate heat and maintain core temperature. This increased oxygen demand can place a strain on the respiratory system.
- Pulmonary Vasoconstriction: Cold stress can lead to vasoconstriction (narrowing) of the blood vessels in the lungs. This constriction can reduce blood flow to the lungs, affecting oxygen uptake and potentially leading to decreased oxygen levels in the blood.
- Peripheral Vasoconstriction: To conserve heat and prioritize blood flow to vital organs, the body undergoes peripheral vasoconstriction. This means that blood vessels in the extremities narrow, reducing blood flow to the skin and extremities. While this helps maintain core temperature, it can result in cold extremities and decreased oxygen supply to peripheral tissues.
- Anaerobic Glycolysis: In response to cold stress, the body may rely more on anaerobic glycolysis, a metabolic pathway that does not require oxygen. While this can provide a short-term energy source, it can also lead to the accumulation of lactic acid and contribute to metabolic acidosis.
- Decrease in PO2 (Partial Pressure of Oxygen) and pH: Cold stress can lead to a decrease in the partial pressure of oxygen (PO2) in the blood, potentially reducing the amount of oxygen available for tissues. Additionally, the increase in anaerobic metabolism can lead to a decrease in pH, resulting in metabolic acidosis.
Overall, these physiological responses to cold stress reflect the body’s efforts to maintain core temperature and ensure essential organ function. However, prolonged or severe cold stress can have detrimental effects on an infant’s health and may require medical intervention to restore normal metabolic and physiological processes.
EvaporationHeat loss through evaporation of moisture on the skin.
ConvectionHeat loss through cooler local air currents
Cooler Air Currents: Convection involves the transfer of heat from the body to the surrounding cooler air. When the air around the body is colder than the body’s temperature, it can absorb heat from the skin’s surface.
ConductionHeat loss through contact with cooler solid object in contact with the baby
Contact with Cooler Objects: Conduction involves the transfer of heat from the body to cooler objects or surfaces in direct contact with the skin. When the skin comes into contact with a colder solid object, such as a cold surface or cold clothing, heat is transferred from the body to that object.
RadiationTransfer of heat from to a cooler object not in contact with the baby
Yes, that’s correct! Anything that has a temperature above absolute zero (which is the lowest temperature theoretically achievable, at approximately -273.15 degrees Celsius or -459.67 degrees Fahrenheit) will continuously emit heat energy in the form of electromagnetic waves,
Nursing Care after Birth
Inmidiate care of the newborn
- Airway
- Breathing
- Temperature. We don’t think about this when we are doing to an 80 year old ! A Baby is different.
AIRWAY/BREATHING SKIN to SKIN with mom If infant is crying or breathing on their own:
Immediate Care for Newborn:
- AIRWAY/BREATHING: If the infant is crying or breathing independently, place the baby skin-to-skin with the mother.
- Monitor vital signs: Check vital signs every 30 minutes for the first 4 hours (q30 x 4), then every hour for the next 2 hours (Q1 x 2), totaling 4 hours. Conduct a vital sign assessment at the 3-hour mark and again at the 4-hour mark.
- Bulb Suction as needed: Minimize excessive use of bulb suction. If suction is necessary, start with the mouth and then proceed to the nose.
AIRWAY/BREATHINGIf infant is apneic or poor color:
Keep the baby warm
Assess HR
Clear airway
Stimulate
Dry vigorously
Remove Secretions
Wipe nose and mouth with gauze to help get rid of excess fluids.
Use bulb syringe if neonate had meconium staining.
No apparent anomalies.
Open Airway“Sniff Position”
If infant is gasping or apneic initiate PPV
In summary, the “Open Airway” and “Sniff Position” are essential steps to ensure that an infant’s airway is clear and properly aligned. If the baby is not breathing or is gasping for breath, further intervention, such as Positive Pressure Ventilation (PPV), may be necessary to provide them with the necessary oxygen.
Indications for Oxygen
Indications for Oxygen Administration in a Baby:
- Increased respiratory effort
- Respiratory distress with apnea
- Tachycardia
- Bradycardia
- Persistent Central Cyanosis