ANTE--PARTUM. Lecture 3. Antepartum YESSSSSS Antepartum Flashcards

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1
Q

HIGH-RISK PREGNANCY

A

A pregnancy in which the life or health of the mother or fetus is compromised.
It can be coincidental or unique to pregnancy

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2
Q

Risk Factors during pregnancy

A

Biophysical
Psychosocial
Socio-demographic
Environmental

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3
Q

Antepartum Testing. When ?

A

To detect potential fetal compromise

32-34 weeks until delivery

Used primarily for women at risk for disrupted fetal oxygenation

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4
Q

BIOPHYSICAL ASSESSMENTS

A

Daily Fetal Movement Count (Kick Count):
The daily fetal movement count, often referred to as kick count, is a simple and non-invasive method for pregnant individuals to monitor their baby’s activity level in the womb. It involves keeping track of the number of times a baby moves or kicks within a specific time period, typically over the course of a day. This assessment is important because reduced fetal movements can sometimes indicate potential problems, such as fetal distress or decreased oxygen supply. Healthcare providers may recommend different guidelines for the number of movements that should be felt within a certain time frame, and any significant deviation from these guidelines might warrant further evaluation.

Ultrasound:
Ultrasound is a common prenatal diagnostic tool that uses sound waves to create images of the developing fetus and the mother’s reproductive organs. It provides valuable information about the baby’s growth, position, anatomy, and overall health. Ultrasounds can be performed at different stages of pregnancy, including the first trimester, second trimester, and third trimester. They are used to confirm pregnancy, estimate gestational age, identify multiple pregnancies, monitor fetal growth, check for abnormalities, and assess various other aspects of fetal development. Ultrasound technology has advanced significantly over the years, allowing for detailed and real-time visualization of the fetus.

Biophysical Profile (BPP):
The biophysical profile is a comprehensive assessment used to evaluate the well-being of a fetus during the third trimester of pregnancy. It combines multiple components to provide a more holistic picture of fetal health. The components typically include:

Fetal Heart Rate Monitoring: This involves assessing the baby’s heart rate using a Doppler device or electronic fetal monitor.

Fetal Breathing Movements: Observation of rhythmic breathing movements by the fetus.

Fetal Movement (Body Movements): Similar to the daily kick count, this component evaluates the fetus’s gross body movements.

Amniotic Fluid Volume: Ultrasound is used to measure the amount of amniotic fluid surrounding the fetus. Adequate amniotic fluid levels are important for fetal protection and development.

Fetal Muscle Tone: This component assesses the presence and quality of fetal muscle tone.

Each component is assigned a score, and the cumulative score is used to assess the overall well-being of the fetus. A low score might indicate a need for further evaluation or intervention.

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5
Q

Get to know your baby’s movements and report any change to your MD, CNM or Healthcare Provider

A

Fetal Movement Counts: Pay attention to your baby’s movement patterns. As your pregnancy progresses, you’ll likely notice a regular pattern of when your baby is most active. Counting the number of movements within a specific time frame, often referred to as a “kick count,” can help you monitor your baby’s activity.

Changes in Movement: If you notice a sudden change in your baby’s movement pattern, such as a significant decrease in movement or a lack of movement for an extended period, it’s important to contact your healthcare provider. Changes in movement could indicate potential issues that need to be evaluated.

Communication with Healthcare Provider: Always communicate any changes in your baby’s movements to your healthcare provider, whether it’s a decrease in movement, an increase in movement, or any other changes that concern you. Your healthcare provider will be able to guide you on whether further assessment is needed.

Monitoring Tools: Some healthcare providers might recommend using specific tools, such as a kick count chart or mobile apps, to help you track your baby’s movements. These tools can provide a structured way to monitor your baby’s activity.

Importance of Monitoring: Monitoring fetal movements is especially important during the third trimester when your baby’s movements become more pronounced. However, it’s generally a good practice to pay attention to movements throughout your pregnancy.

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6
Q
  • Ultrasound: can be abdominal (Later stages)or transvaginal (inside vagina, used in early staged coz it’s more precise accurate since it’s closer to the reproductive organs )
A

Abdominal Ultrasound:

Procedure: In abdominal ultrasound, a handheld device called a transducer is moved over the skin of the abdomen. A gel is applied to the skin to help transmit the sound waves and improve image quality.

Application: Abdominal ultrasounds are commonly used to examine the organs and structures within the abdominal cavity, such as the liver, gallbladder, kidneys, pancreas, spleen, and aorta. It’s also frequently used for pregnancy imaging, especially in the later stages.

Advantages: Non-invasive, does not require any insertion into the body. Can provide a broad overview of abdominal structures.

Transvaginal Ultrasound:

Procedure: In transvaginal ultrasound, a specially designed transducer is inserted into the vagina. This allows for closer proximity to the pelvic organs and structures.

Application: Transvaginal ultrasounds are primarily used to examine the reproductive organs, such as the uterus and ovaries. They are especially useful for early pregnancy imaging, assessing gynecological conditions, and evaluating pelvic pain or abnormal bleeding.

Advantages: Offers higher-resolution images of the pelvic organs due to the closer proximity of the transducer. Provides clearer images, especially in early pregnancy.

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7
Q

Transvaginal ultrasound

  • Transvaginal used mainly in in the first trimester - provides greater detail and can dx IUP and establish GA earlier
  • Levels of ultrasonography:
    **Standard – GA, AFI’s etc.
    **Limited – e.g., check for vertex presentation, FHR
    **Specialized- suspected anatomical or physiological abnormal fetus
A

You’re absolutely right, transvaginal ultrasound is often used in the first trimester of pregnancy and provides higher resolution images that can aid in diagnosing various conditions, including confirming an intrauterine pregnancy (IUP) and establishing gestational age (GA) more accurately. The ability to get closer to the reproductive organs through the vaginal approach allows for more precise measurements and imaging during this early stage of pregnancy.

Regarding the levels of ultrasonography you mentioned, you’ve provided an accurate breakdown of the different types:

Standard Ultrasonography:
This is a comprehensive ultrasound examination that includes assessing various aspects of pregnancy. It can involve measurements of gestational age, amniotic fluid levels (AFL), and the general well-being of the fetus. Standard ultrasonography is often used to monitor the overall progress of the pregnancy and the health of the developing fetus.

Limited Ultrasonography:
Limited ultrasound exams focus on specific aspects of the pregnancy. They are often done for targeted purposes, such as checking for fetal heart rate (FHR) or confirming the fetal presentation (e.g., vertex presentation) to ensure proper positioning for childbirth. These exams are more streamlined and address specific concerns.

Specialized Ultrasonography:
Specialized ultrasounds are used when there are suspected anatomical or physiological abnormalities in the fetus. These exams are more detailed and thorough, aiming to provide in-depth information about specific areas of concern. They are often performed by experts in fetal medicine or specialized ultrasound technicians.

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8
Q

Indications For Use. Ultrasound

A
  • Fetal Heart Activity
  • Gestational Age
  • Fetal Growth
  • Fetal Anatomy
  • Fetal Genetic
  • Fetal Position
  • Disorders and Physical Anomalies
  • Placental Position and Function
  • Adjunct to other tests
  • Fetal Well Being
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9
Q

Ultrasound to Determine Gestational Age
Fetal Growth. Todas estan hechas con ultrasonido

A

Recommended Method of Dating:
Ultrasound is one of the most accurate methods for determining gestational age during pregnancy. It provides visual information about the fetus’s development, which helps healthcare providers estimate how far along a pregnancy is.

Most Accurate Between 14-22 Weeks:
While ultrasound can be performed at various stages of pregnancy, the most accurate determination of gestational age typically occurs between 14 and 22 weeks. During this period, various fetal structures and measurements can be observed with high precision.

Gestational Sac Dimensions (8 Weeks):
During early pregnancy, around 8 weeks gestation, the dimensions of the gestational sac can provide information about the development of the embryo.

Crown/Rump Length (7-12 Weeks):
The crown-rump length (CRL) measurement is taken from the top of the baby’s head (crown) to the bottom of its buttocks (rump). It’s a reliable indicator of gestational age and is most accurate between 7 and 12 weeks.

BPD (Biparietal Diameter) and Femur Length (12 Weeks):
The biparietal diameter (BPD) is the measurement between the two sides of the baby’s head. It’s commonly used to estimate gestational age and assess growth. Femur length, the measurement of the thigh bone, is another indicator of fetal size.

Serial Evaluations for Fetal Growth:
Serial evaluations involve tracking the growth of specific fetal measurements over time. This includes monitoring changes in the biparietal diameter, limb length, and abdominal circumference. These measurements are essential to assess how well the fetus is growing and to detect any potential growth abnormalities.

Abdominal Circumference:
Abdominal circumference is an important measurement that reflects the size of the fetal abdomen. It’s used to assess fetal growth and well-being, as abnormalities in abdominal circumference can indicate issues such as intrauterine growth restriction (IUGR).

By combining various measurements taken during ultrasound examinations, healthcare providers can create a comprehensive picture of the fetus’s development, gestational age, and growth trajectory.

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10
Q

Biparietal Diameter (BPD) to determine
Gestational age
After 12 weeks (BPD has 3 letters and 12 weeks = 3 months )

A

Biparietal etymology

The term “biparietal” is derived from two Latin words: “bi” meaning “two” and “parietal” referring to the parietal bones of the skull. The parietal bones are two of the major cranial bones that form the upper sides and roof of the skull.

In medical and anatomical terminology, “biparietal” is often used in reference to the biparietal diameter (BPD), which is a measurement taken during prenatal ultrasound to assess the size of the fetal head. The biparietal diameter is the distance between the two parietal bones on either side of the fetal skull. It’s an important measurement used to estimate gestational age and monitor fetal growth during pregnancy.

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11
Q

Fetal Well-Being

A

Doppler Blood Flow Analysis:
Doppler ultrasound is a technique that measures blood flow within the blood vessels. In obstetrics, it is often used to assess blood flow in the umbilical cord and other fetal vessels. Abnormal blood flow patterns can indicate potential issues such as placental insufficiency or fetal distress.

Amniotic Fluid Volume (AFV) Assessment:
The level of amniotic fluid surrounding the fetus is an important indicator of fetal well-being. Too much or too little amniotic fluid can be a sign of problems. An ultrasound can be used to measure the amniotic fluid volume, helping to assess fetal health.

Non-Stress Test (NST):
The non-stress test is a simple and non-invasive test used to evaluate the fetal heart rate in response to the baby’s movements. During the test, the fetal heart rate is monitored using a fetal heart rate monitor. An acceleration in the heart rate when the baby moves is a positive sign, indicating the well-being of the fetus. Because it’s responding to the movement and the heart is beating faster to adjust to the higher demand of oxygen requested by the tissues.

Biophysical Profile (BPP):
The biophysical profile is a comprehensive assessment that combines multiple factors to evaluate fetal well-being. These factors typically include fetal heart rate monitoring (NST), fetal breathing movements, fetal movement, amniotic fluid volume assessment, and fetal muscle tone. Each factor is assigned a score, and the cumulative score helps determine the overall health of the fetus.

Modified Biophysical Profile:
The modified biophysical profile is a variation of the standard BPP that focuses on fewer parameters. It often includes the NST and the assessment of amniotic fluid volume. This streamlined version is sometimes used when a full BPP is not necessary or feasible.

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12
Q

Biophysical Profile (BPP)

There are 5

A

-Fetal Breathing Movements (2)
-Gross Body Movements (2) can baby move
-Fetal Tone (2) can baby clinch fist
-Reactive Heart Rate (NST) (2)
-Qualitative amniotic fluid volume (AFI) (2)

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13
Q

Breakdown of the components of a Biophysical Profile (BPP)

Here’s the standard scoring breakdown for a
BPP:

Normal: 2 points
Abnormal: 0 points

A

Biophysical Profile (BPP):

The BPP evaluates the fetal well-being by assessing five different components:

Fetal Breathing Movements:

Normal (Score = 2): 1 or more episodes of fetal breathing movements lasting >20 seconds within 30 minutes. Meaning the baby took at least 20 sec or more in the last 30 min (this = 2, meaning aprovado)
Abnormal (Score = 0): Absent or no episode of fetal breathing movements lasting >20 seconds within 30 minutes.
Gross Body Movements:

Normal (Score = 2): 2 or more discrete body/limb movements within 30 minutes (episodes of continuous movement are considered as a single movement).
Abnormal (Score = 0): Less than 2 episodes of body/limb movements within 30 minutes.
Fetal Tone:

Normal (Score = 2): 1 or more episodes of active extension with return to flexion of fetal limb(s) or trunk (normal tone). Opening and closing of the hand are considered normal tone.
Abnormal (Score = 0): Slow extension with return to partial flexion, movement of a limb in full extension, absent fetal movement, or partially open fetal hand.
Reactive Fetal Heart Rate (FHR):

Normal (Score = 2): 2 or more episodes of acceleration of ≥15 beats per minute (bpm) and of >15 seconds associated with fetal movement within 20 minutes.
Abnormal (Score = 0): 1 or more episodes of acceleration of fetal heart rate of <15 bpm within 20 minutes.
Qualitative Amniotic Fluid Volume (AFV):

Normal (Score = 2): 1 or more pockets of amniotic fluid measuring ≥2 cm in the vertical axis.
Abnormal (Score = 0): Either no pockets of amniotic fluid or the largest pocket measuring <2 cm in the vertical axis.

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14
Q

INTERPRETATION of BPP

A

8-10 = Normal, Low Risk
4-6 = Suspected Chronic Asphyxia
2 = Strong Suspicion of Asphyxia

8-10: Normal, Low Risk: A BPP score of 8 to 10 points is considered normal and indicates that the baby’s well-being is generally healthy. This range suggests that the components assessed in the BPP, such as fetal movements, breathing, tone, heart rate, and amniotic fluid, are within expected parameters.

4-6: Suspected Chronic Asphyxia: A BPP score of 4 to 6 points indicates a potential concern about the baby’s well-being, specifically related to chronic asphyxia. Asphyxia refers to inadequate oxygen supply to the fetus. A score in this range suggests that some components of the BPP may be abnormal, which could indicate that the baby is experiencing challenges related to oxygenation.

2: Strong Suspicion of Asphyxia: A BPP score of 2 points is indicative of a strong suspicion of asphyxia, suggesting that there are significant concerns about the baby’s well-being and oxygen supply. A score of 2 points implies that several components of the BPP are likely showing abnormalities, indicating potential issues with the baby’s health and oxygenation.

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15
Q
  • Amniotic Fluid Index (AFI)
  • Amniotic Fluid Volume (AVI)
A

Measures the vertical depths of the largest pocket of amniotic fluid in all four quadrants surrounding the maternal umbilicus and totaled

Amniotic Fluid Index (AFI):
The Amniotic Fluid Index (AFI) is a measurement used to assess the amount of amniotic fluid present in the uterus during pregnancy. Amniotic fluid is a liquid that surrounds and protects the developing fetus. It also plays a crucial role in maintaining a stable environment for fetal growth and development. The AFI is typically measured using ultrasound.

The AFI is calculated by dividing the uterus into four quadrants and measuring the deepest vertical pocket of amniotic fluid in each quadrant. The measurements from the four pockets are then added together to determine the AFI. This measurement helps healthcare providers assess the volume of amniotic fluid and detect any abnormalities.

Amniotic Fluid Volume (AFV):
“Amniotic Fluid Volume” is a general term that refers to the amount of fluid within the amniotic sac during pregnancy. The amniotic sac is the membrane that surrounds the fetus and contains the amniotic fluid. The term itself doesn’t represent a specific measurement or test like AFI does. Instead, it’s a broader description of the fluid surrounding the fetus.

In summary, the Amniotic Fluid Index (AFI) is a specific measurement used to assess the quantity of amniotic fluid in the uterus during pregnancy, while “Amniotic Fluid Volume” (AFV) is a general term referring to the fluid surrounding the fetus within the amniotic sac. If you’re discussing amniotic fluid levels in a clinical context, you’re likely referring to AFI as the specific measurement used to assess fluid volume.

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16
Q

AFI or AVI measures four quadrants. 5-25 cm is normal.

A

The amniotic fluid index (AFI) is a measurement that quantifies the amount of amniotic fluid in the uterus. It’s typically measured in centimeters and is used to assess the adequacy of the amniotic fluid level. An AFI of 5-25 cm is generally considered normal. An AFI below 5 cm might indicate oligohydramnios, which is a lower-than-normal level of amniotic fluid, while an AFI above 25 cm could indicate polyhydramnios, which is an excessive amount of amniotic fluid.

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17
Q

Biochemical Assessment.
Procedures to obtain specimens:

A

Amniocentesis: This is a prenatal diagnostic procedure in which a small amount of amniotic fluid is withdrawn from the amniotic sac surrounding the fetus. It’s typically performed between the 15th and 20th weeks of pregnancy. The amniotic fluid contains cells and biochemical markers that can provide information about the fetus’s genetic makeup, health, and development. Amniocentesis is often used to screen for genetic conditions such as Down syndrome, as well as to detect neural tube defects and certain genetic disorders.

Chorionic Villus Sampling (CVS): CVS is another prenatal diagnostic procedure that involves sampling a tiny piece of tissue from the placenta, specifically the chorionic villi. This procedure is usually done between the 10th and 13th weeks of pregnancy. The chorionic villi have the same genetic information as the fetus and can provide insights into genetic conditions and chromosomal abnormalities.

Maternal Assays: These are blood tests performed on the pregnant mother to assess various markers that can indicate potential issues with the pregnancy. These tests often measure hormone levels, proteins, and other substances in the mother’s blood that might be indicative of certain conditions in the fetus, such as neural tube defects or chromosomal abnormalities. Examples of maternal assays include the multiple marker screen and non-invasive prenatal testing (NIPT).

Percutaneous Umbilical Blood Sampling (PUBS): Also known as cordocentesis, this procedure involves withdrawing a small sample of blood from the umbilical cord. It is typically used in cases where more direct and immediate information about the fetus’s health is needed. PUBS can provide information about blood disorders, infections, and other conditions affecting the fetus’s blood.

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18
Q

AMNIOCENTESIS

A

-Genetic and chromosomal abnormalities (15- 20 weks)
-Fetal Lung Maturity
-Rh isoimmunization status and severity of hemolytic anemia
-AFP (Alpha Feto Protein) levels which indicate anatomic abnormalities (Fetal Nutrition: AFP is produced by the fetal liver and plays a role in transporting nutrients from the mother’s bloodstream to the developing fetus. It helps ensure that the fetus receives the necessary nutrients for growth and development.)

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19
Q

2 Ways of Measuring the Infant’s Lung Maturity

A

Lecithin to Sphingomyelin (L/S) Ratio:
The Lecithin to Sphingomyelin (L/S) ratio is a test that assesses the relative levels of two specific types of phospholipids in the amniotic fluid. Phospholipids are important components of surfactant, a substance that lines the alveoli (air sacs) in the lungs and helps reduce surface tension, preventing the alveoli from collapsing. The L/S ratio is calculated by dividing the concentration of lecithin (also known as phosphatidylcholine) by the concentration of sphingomyelin.

2 or More: An L/S ratio of 2 or more is generally indicative of fetal lung maturity and suggests a low risk of infant respiratory distress syndrome (RDS). This means that there is an adequate amount of surfactant in the fetal lungs to support normal breathing after birth.
1.5 or Less: An L/S ratio of 1.5 or less is associated with a higher risk of RDS. A lower ratio indicates that there might be insufficient surfactant present, which could lead to respiratory difficulties for the newborn.
Phosphatidylglycerol (PG):
Phosphatidylglycerol is another component of surfactant, and its presence in the amniotic fluid is an indicator of fetal lung maturity.

Presence of PG: The presence of phosphatidylglycerol in the amniotic fluid is a positive sign of fetal lung maturity. It suggests that the fetal lungs are producing surfactant, which is crucial for proper lung function after birth.

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20
Q

ACOG recommendations as of August 2017

  • from the American College of Obstetricians and Gynecologists (ACOG) as of August 2017 regarding the administration of antenatal corticosteroids (also known as betamethasone or BMZ) for fetal lung maturation in cases of anticipated preterm birth. These recommendations aim to reduce the risk of respiratory complications in premature infants.
A

Timing of Delivery and Fetal Lung Maturity:
ACOG’s recommendation states that if a patient is in a situation where delivery is indicated, it should be carried out regardless of fetal lung maturity status. In other words, if there is a medical reason for delivery, the need for delivering the baby takes precedence over assessing fetal lung maturity.

Administration of BMZ Before 34 Weeks:

If a patient is less than 34 weeks pregnant and is facing imminent delivery within the next 7 days, and if they haven’t received antenatal corticosteroids (BMZ) within the last 14 days, then ACOG recommends the administration of BMZ to promote fetal lung maturation.
Administration of BMZ Between 34 and 36.6 Weeks:

If a patient is between 34 and 36.6 weeks pregnant and is at risk of preterm birth within the next 7 days, and they either haven’t received BMZ before or their prior course was more than 14 days ago, then ACOG recommends considering the administration of BMZ.

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21
Q

Complications
Less than 1%. Chorionic Villus Sampling (CVS)
10-12 weeks sometimes 13

A

Complications of CVS for the Mother:

Infection: Any medical procedure carries a risk of infection, but the risk of infection after CVS is relatively low.
Hemorrhage: There’s a small chance of bleeding after the procedure due to the needle insertion. This is usually minimal and self-limited.
Damage to Bladder or Intestines: Although extremely rare, there’s a possibility of accidental damage to nearby organs during the procedure.
Miscarriage: The risk of miscarriage is a concern with any invasive prenatal procedure. However, modern techniques have reduced this risk significantly, and the risk associated with CVS is generally considered to be less than 1%.
Preterm Labor (PTL): In some cases, CVS might trigger contractions that could lead to preterm labor. However, the incidence of this complication is low.
Leakage of Amniotic Fluid (AF): The risk of amniotic fluid leakage is minimal, but it’s still important to monitor for this potential complication.
Rh Sensitization: This refers to the development of antibodies in the mother’s blood that could affect subsequent pregnancies. This risk is relatively low and can be managed with appropriate medical interventions.
Complications of CVS for the Baby:

Death: While extremely rare, there’s a very small chance that the procedure could lead to fetal demise.
Hemorrhage: Similar to the risk in mothers, there’s a low risk of bleeding for the baby due to the needle insertion.
Infection: The risk of infection affecting the baby is generally low.

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22
Q

Chorionic Villus Sampling (CVS)
10-12 weeks.

A
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23
Q

Nursing care

A

Explain Procedure and provide comfort measures and emotional support
Fetal Monitoring
Patient teaching:
Report leaking fluid
Abdominal pain
Bleeding
Decreased Fetal movement
Fever
Rhogham to RH- women

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24
Q

Fetal Assessment via Electronic Fetal Monitoring

A

Non-Stress Test (NST):
The Non-Stress Test is a relatively simple and non-invasive procedure that monitors the fetal heart rate and its variability in response to the natural movements of the fetus. It’s typically performed during the third trimester of pregnancy and involves placing two monitors on the mother’s abdomen:

Fetal Heart Rate Monitor: This monitor records the fetal heart rate over a specific period, usually around 20 to 30 minutes. It detects accelerations in the fetal heart rate that are associated with fetal movement.

Tocodynamometer: This monitor measures uterine contractions, which can help correlate any changes in the fetal heart rate with contractions.

During the test, the healthcare provider assesses the fetal heart rate patterns for baseline variability and the presence of accelerations, which are positive signs of fetal well-being. A reactive NST is characterized by the presence of a certain number of accelerations within a specified time frame, indicating that the fetus is receiving an adequate oxygen supply.

Contraction Stress Test (CST or OST):
The Contraction Stress Test, also known as the Oxytocin Stress Test (OST), is a more intensive test used to assess the ability of the fetus to withstand the stress of labor contractions. This test is usually reserved for cases where there might be concerns about the fetus’s oxygen supply during labor.

The CST involves stimulating uterine contractions, either naturally through nipple stimulation or artificially using a medication called oxytocin. The goal is to simulate the stress of labor contractions and observe the fetal heart rate response. Similar to the NST, monitors are placed on the mother’s abdomen to measure both fetal heart rate and uterine contractions.

Interpretation of the CST results involves evaluating the fetal heart rate patterns in response to contractions. A negative CST result shows that the fetus’s heart rate remains relatively stable during contractions, indicating a reassuring sign of fetal well-being. A positive CST result, on the other hand, indicates that the fetal heart rate decelerates significantly during contractions, which could suggest inadequate oxygen supply and might require further evaluation.

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25
Q

Fetal Assessment via Electronic Fetal Monitoring

A

Electronic Fetal Monitoring (EFM) is a medical procedure used to assess the well-being of a fetus during pregnancy and labor. It involves the use of electronic devices to monitor the fetal heart rate and uterine contractions. EFM is commonly used to determine the timing of childbirth for women who are at risk for various complications, including uteroplacental insufficiency (UPI). Uteroplacental insufficiency refers to a condition where the placenta is not providing enough oxygen and nutrients to the fetus.

Here’s how the process of fetal assessment via Electronic Fetal Monitoring might work:

Identification of High-Risk Patients: Healthcare providers identify pregnant women who are at high risk for uteroplacental insufficiency. These risk factors might include conditions like preeclampsia, gestational diabetes, chronic hypertension, intrauterine growth restriction (IUGR), and certain maternal medical conditions.

Gestational Age: The timing of fetal assessment via EFM can vary depending on the gestational age of the fetus. In the case mentioned (women at risk for UPI), assessment is suggested around 32-34 weeks of pregnancy. This is a critical time as the fetus is nearing term and any signs of distress need to be closely monitored.

Frequency of Monitoring: High-risk patients are typically monitored 1-2 times a week using EFM. This regular monitoring allows healthcare providers to closely track the fetal heart rate and uterine contractions and detect any potential issues promptly.

Electronic Fetal Monitoring: During the EFM procedure, two sensors are typically used:

Fetal Heart Rate Monitor: This sensor is placed on the mother’s abdomen to monitor the fetal heart rate. Changes in the fetal heart rate pattern can indicate distress or potential oxygen deprivation.
Uterine Contraction Monitor: Another sensor measures the frequency and strength of uterine contractions. This helps assess the stress placed on the fetus during contractions.
Data Interpretation: The data from EFM is continuously displayed on a monitor, allowing healthcare providers to observe the fetal heart rate and contractions in real-time. They will look for patterns and changes that could indicate fetal distress. There are different patterns that may be concerning, such as decreased variability in the fetal heart rate, late decelerations (heart rate drops after contractions), and other irregularities.

Intervention: If the EFM indicates any signs of fetal distress or compromised well-being, the healthcare team will intervene accordingly. This could involve adjusting the mother’s position, providing oxygen, increasing intravenous fluids, or considering more urgent interventions such as an emergency cesarean section.

It’s important to note that while EFM is a valuable tool for fetal assessment, it is not without limitations and can sometimes result in false positives or false negatives. It requires skilled interpretation by healthcare providers who are experienced in understanding fetal heart rate patterns.

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26
Q

Fetal Heart Monitoring

A

NON-STRESS TEST:

  • Evaluate FHR during movement.
  • Reactive/Nonreactive
  • Reactive = 2 Accelerations in 20 minutes.
  • Accelerations are FHR equal or greater than 15 BPM over baseline lasting 15 seconds or more.

Reactive NST Example:
In a reactive NST, the fetal heart rate shows the desired pattern of accelerations in response to fetal movement.

During a 20-minute monitoring period, the following pattern is observed:

Acceleration 1: Fetal heart rate increases by 25 BPM above the baseline of 140 BPM for 20 seconds in response to fetal movement.
Acceleration 2: Fetal heart rate increases by 30 BPM above the baseline of 150 BPM for 25 seconds in response to another fetal movement.
Result: This NST is considered reactive because it meets the criteria of having at least two accelerations of 15 BPM or more above the baseline, each lasting for at least 15 seconds, within the 20-minute monitoring period. A reactive NST indicates that the fetus is responding appropriately to its movements and is likely receiving adequate oxygen and nutrients.

Nonreactive NST Example:
In a nonreactive NST, the fetal heart rate does not show the desired pattern of accelerations in response to fetal movement.

During a 20-minute monitoring period, the following pattern is observed:

Minimal or no accelerations in the fetal heart rate are observed in response to fetal movements.
The baseline heart rate remains relatively stable around 130 BPM.
Result: This NST is considered nonreactive because it does not meet the criteria of having at least two accelerations of 15 BPM or more above the baseline, each lasting for at least 15 seconds, within the 20-minute monitoring period. A nonreactive NST may raise concerns about fetal well-being and might prompt further assessment and evaluation to determine the underlying cause of the nonreactive result.

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27
Q

CONTRACTION STRESS TEST. To see if the baby can handle the contractions in the future during delivery and still be able to breath while this is happening. Negative is good (A negative CST result means that there are no significant decelerations in the fetal heart rate during contractions. )

A

Contraction Stress Test (CST): A CST is a diagnostic test conducted during pregnancy to evaluate how the fetus will tolerate the stress of labor contractions. It helps determine if the fetus is receiving enough oxygen during contractions.

Endogenous Oxytocin: Oxytocin is a hormone naturally produced by the body, often referred to as the “love hormone” because it plays a role in social bonding and childbirth. In the context of a CST, endogenous oxytocin refers to the oxytocin naturally produced by the mother’s body during contractions.

Exogenous Oxytocin: Exogenous oxytocin refers to oxytocin that is administered externally, usually through medication. This can be done to induce or augment labor contractions during the CST or other labor-related procedures.

FHT (Fetal Heart Tracing): FHT refers to monitoring the fetal heart rate, which can provide important information about the well-being of the fetus. Changes in the fetal heart rate can indicate how the fetus is responding to various factors, including contractions.

Decelerations: Fetal heart rate decelerations are temporary drops in the fetal heart rate. They can be categorized as early decelerations, late decelerations, and variable decelerations. The timing and pattern of decelerations provide insights into fetal well-being.

Based on your provided information, it seems you’re discussing the results of the Contraction Stress Test and their interpretation:

Negative Result: A negative CST result means that there are no significant decelerations in the fetal heart rate during contractions. Specifically, there are no decelerations observed with at least three uterine contractions (UCs) lasting 40-60 seconds each in a 10-minute period. This is generally considered a reassuring sign, indicating that the fetus is tolerating the stress of contractions well. Meaning that even if the baby is under stress (contractions) he can still receive oxygen and keep a constant heart rate.

Positive Result: A positive CST result indicates that decelerations in the fetal heart rate are observed with 50% or more of the uterine contractions. This could be a sign that the fetus is not receiving enough oxygen during contractions, which might raise concerns about the fetus’s well-being.

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28
Q

Contraindications of CST

A

PTL (Preterm Labor): Preterm labor refers to labor that starts before 37 weeks of pregnancy. Performing a CST in the presence of preterm labor might not be advisable, as the contractions induced during the test could potentially worsen the existing condition and lead to premature birth.

Placenta Previa: Placenta previa is a condition where the placenta partially or completely covers the cervix. Due to the risk of bleeding associated with placenta previa, performing a CST could potentially trigger bleeding or other complications.

Cervical Insufficiency: Cervical insufficiency, also known as an incompetent cervix, is a condition where the cervix begins to dilate and efface (thin out) prematurely, often leading to preterm labor. In this situation, performing a CST could further contribute to cervical changes and potentially lead to complications.

Multiple Gestation: When a pregnant person is carrying multiple fetuses (twins, triplets, etc.), there is an increased risk of preterm labor and other complications. Inducing contractions during a CST might pose additional risks in these cases.

Previous C/S (Previous Cesarean Section): If a person has had a previous cesarean section (C-section), there could be scar tissue on the uterus. Inducing contractions during a CST might put stress on the uterine scar, potentially increasing the risk of uterine rupture.

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29
Q

32 through 40 slides

A
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30
Q

SPONTANEOUS ABORTION

A

Threatened Abortion: This term is used when a pregnant person experiences vaginal bleeding and possibly mild cramping, but the cervix is still closed, and the pregnancy remains viable. In many cases, the bleeding stops, and the pregnancy continues without further complications.

Inevitable Abortion: Inevitable abortion occurs when vaginal bleeding and cramping become more pronounced, and there may be signs that the cervix is opening. This suggests that a miscarriage is likely to occur, and there is no way to prevent it.

Incomplete Abortion: An incomplete abortion happens when only part of the products of conception (fetus, placenta, etc.) are expelled from the uterus. This can lead to persistent bleeding and infection risks, and medical intervention may be needed to remove the remaining tissue.

Complete Abortion: In a complete abortion, all of the products of conception are expelled from the uterus. The bleeding and cramping typically subside after this occurs.

Missed Abortion: A missed abortion (also called a missed miscarriage) refers to a situation where the fetus has died, but the body has not yet recognized the loss. There might be no symptoms, and the pregnancy might continue without fetal development. Medical intervention is often required to manage the situation.

Recurrent (Habitual) Abortion: Recurrent or habitual abortion refers to the occurrence of multiple consecutive miscarriages. If a person experiences three or more consecutive miscarriages, it’s considered habitual, and medical evaluation is often conducted to identify potential underlying causes.

Sepsis: Sepsis is a severe response to infection that can lead to tissue damage, organ failure, and even death. In the context of miscarriage, sepsis can occur if an infection develops after a miscarriage and is not promptly treated.

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31
Q

SPONTANEOUS ABORTIONSigns and Symptoms. Dependent on duration of pregnancy

Spontaneous abortion, commonly known as a miscarriage, refers to the natural loss of a pregnancy before the 20th week of gestation. It occurs when the fetus and other products of conception are expelled from the uterus due to various factors, often before the pregnancy reaches a point where the fetus is viable outside the womb. Spontaneous abortion can happen for a variety of reasons, including genetic abnormalities, hormonal imbalances, uterine abnormalities, infections, and more.

A

Vaginal Bleeding: Vaginal bleeding is a common symptom of miscarriage. It can range from light spotting to heavy bleeding. The color of the blood can also vary, from bright red to brownish. In the early stages of pregnancy, vaginal bleeding might be the only noticeable symptom of a miscarriage.

Abdominal Pain: Abdominal pain is another common symptom associated with miscarriage. The pain might feel like cramps and can vary in intensity. The pain might be similar to menstrual cramps in the early stages of pregnancy.

Cramping: Cramping is often felt along with abdominal pain and can be quite uncomfortable. The intensity and duration of cramps can vary.

Pelvic Pressure: As the pregnancy progresses and the uterus expands, you might feel increased pressure in the pelvic region. This pressure can be more pronounced during a miscarriage.

Low Back Pain: Low back pain is also a symptom that some individuals experience during a miscarriage. It can be similar to the back pain experienced during menstruation

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32
Q

SPONTANEOUS ABORTIONRisk Factors:

A

Congenital Malformations: Congenital malformations or abnormalities in the developing fetus can increase the risk of miscarriage, particularly during the first trimester of pregnancy. These abnormalities can affect the fetus’s development and viability, leading to a natural loss of pregnancy.

Maternal Infections: Infections during pregnancy can pose a risk to both the mother and the developing fetus. Some infections, such as certain types of bacterial or viral infections, can increase the risk of miscarriage due to their impact on fetal development.

Maternal Endocrine Problems: Hormonal imbalances or endocrine disorders in the mother can affect the pregnancy’s progression and increase the risk of miscarriage. Hormones play a crucial role in maintaining a healthy pregnancy.

AMA (Advanced Maternal Age): Advanced maternal age, often defined as being 35 years or older, is associated with an increased risk of miscarriage. This increased risk is thought to be due to factors such as higher rates of genetic abnormalities in pregnancies of older individuals.

Previous Loss: Having a history of previous miscarriages can increase the risk of experiencing another miscarriage. Recurrent miscarriages might be indicative of underlying medical conditions that need to be addressed.

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33
Q

SPONTANEOUS ABORTION(not induced by doctor) Management

A

Bedrest and Fluids (Threatened): In cases of threatened abortion, where there is vaginal bleeding but the cervix is closed and the pregnancy is still viable, healthcare providers might recommend bed rest and increased fluid intake to reduce stress and pressure on the body.

D & C (Dilation and Curettage (cuillère=scoop out)) or Suction Curettage: A D & C procedure involves dilating the cervix and using surgical instruments to remove the remaining contents of the uterus after a miscarriage. This might be recommended in cases of incomplete abortion or if there are concerns about infection.

D & E (Dilation and Evacuation): In the second trimester, a D & E procedure might be performed if the pregnancy loss occurs later on. This procedure involves dilation of the cervix and evacuation of the uterine contents.

Antibiotics (Missed, Septic): Antibiotics might be prescribed if there is an infection associated with the miscarriage (septic miscarriage) or if there are concerns about infection following a missed abortion.

Misoprostol: Misoprostol is a medication that can be used to induce contractions and help expel the contents of the uterus after a miscarriage. It’s often used as an alternative to surgical procedures, especially in cases of incomplete or missed abortion.

Pain Medications: Pain medications might be prescribed to help manage the discomfort or pain associated with the miscarriage and its aftermath.

RhoGAM (Rh-): RhoGAM is a medication given to Rh-negative pregnant individuals to prevent the development of antibodies that could harm future pregnancies. It might be recommended after a miscarriage if there’s a risk of Rh sensitization.

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34
Q

Dialation and Curettage

A
  1. Dilation (D): The cervix, the narrow passage that connects the vagina to the uterus, needs to be dilated or widened to create access to the uterine cavity. This is typically done using special dilators, which gradually increase in size to gently expand the cervix.
  2. Curettage (C): Curettage involves the removal of tissue from the inner lining of the uterus. A curette, a spoon-shaped surgical instrument, is used to carefully scrape away the tissue lining. This can include removing abnormal tissue growth, uterine polyps, or, in the context of a miscarriage, the products of conception that remain in the uterus after the natural loss of a pregnancy.

D&C might be performed for various reasons, including:

Miscarriage Management: In cases of incomplete miscarriage, where not all pregnancy tissue is expelled naturally, a D&C might be performed to remove the remaining tissue and reduce the risk of infection or complications.

Diagnosis and Treatment: D&C can be used to diagnose and treat conditions such as abnormal uterine bleeding, uterine polyps, endometrial hyperplasia (excessive growth of the uterine lining), or certain types of precancerous or cancerous conditions.

Investigation: If a healthcare provider suspects an abnormality, such as during certain diagnostic procedures like hysteroscopy, they might perform a D&C to obtain tissue samples for further examination.

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35
Q

Induced Therapeutic Abortion

A

EAB (Elective Abortion): EAB stands for “Elective Abortion.” This refers to the purposeful interruption of a pregnancy for non-medical reasons, typically by choice of the pregnant individual. EAB is often chosen when the pregnancy is unwanted, and there are no medical indications for terminating the pregnancy. The decision to undergo an elective abortion is a personal and private one, and it’s made based on a variety of individual, social, and ethical factors.

TAB (Therapeutic Abortion): TAB stands for “Therapeutic Abortion.” This type of abortion is carried out for medical reasons, either for the health of the pregnant individual or due to fetal disorders. There are two main categories within therapeutic abortion:

Maternal Disorders: In cases where continuing the pregnancy poses a serious risk to the health or life of the pregnant person, a therapeutic abortion might be recommended. This could be due to underlying health conditions or complications that could be aggravated by the pregnancy.

Fetal Disorders: Therapeutic abortion might also be considered if the fetus has been diagnosed with severe abnormalities or disorders that are incompatible with life or could lead to serious health challenges after birth.

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36
Q

slide 47-48

A
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37
Q

A 2012 study of more than 9,000 women found that when women got no-cost birth control, the number of unplanned pregnancies and abortions fell by between 62 and 78 percent.

A

.

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38
Q

Since Roe vs. Wade

A

New Supreme Court decision leaves us in uncharted
territory.

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39
Q

Abortion Procedure:Counseling

A

Regardless of personal views on abortion, nurses who provide care to women seeking abortion have an ethical responsibility to counsel women about their options and to make appropriate referrals

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40
Q

Counseling

A
  • Respectful, non-judgmental communication
  • What the client can expect before, during and after the procedure
  • Clear instruction on after care and complications to report
  • Risks and benefits of what is available
  • Confirmation there is no coercion in the decision
  • Where to go for follow up care
  • Pain management
  • Available support (eg. Post counseling)
  • Contraception information to prevent further pregnancy including the option for LARC’s at the time of the procedure (Long-Acting Reversible Contraceptives (LARC):
    LARC methods are highly effective, reversible contraception options that require minimal user intervention. They include:

IUDs: (intrauterine device) Hormonal or copper-based IUDs can prevent pregnancy for several years. They are inserted into the uterus by a healthcare provider.
Implants: A small rod is inserted under the skin, releasing hormones to prevent pregnancy for several years.)

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41
Q

H&P. History and Physical

A
  • Assess for co-morbidities and possible contraindications to any procedure
  • Confirm IUP (as opposed to ectopic)
  • Confirm gestational age (LMP)
  • Rh status (Rhogam prophylaxis within 72 hours if needed)
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42
Q

Medical Abortions

A

medical abortions, which are non-surgical methods for terminating pregnancies. Here’s an explanation of the points you’ve mentioned:

Available Time Frame: In the US, medical abortions are typically available for pregnancies up to nine weeks after the last menstrual period (LMP). 2 months and 1 week

Methods:

Methotrexate and Misoprostol: This combination is used for pregnancies up to seven weeks after LMP. Methotrexate interferes with cell reproduction by blocking folic acid metabolism. Misoprostol is used later to cause uterine contractions and empty the uterus.
Misoprostol Alone: Misoprostol can be used alone for pregnancies up to ten weeks after LMP. It stimulates uterine contractions, leading to the expulsion of pregnancy tissue.
Mifepristone (RU-486): Mifepristone, also known as RU-486, is used up to ten weeks after LMP. It blocks the hormone progesterone, which is essential for maintaining pregnancy. The subsequent use of misoprostol causes uterine contractions to expel the pregnancy.
Complications: Medical abortions are generally considered safe with a low rate of complications. However, potential side effects and risks include heavy bleeding, cramping, nausea, vomiting, diarrhea, and incomplete abortion requiring further intervention.

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43
Q

Surgical Abortions : Dilation and Curettage (D&C) 14-16 w

A
  1. A hollow curette (tube) is inserted into the uterus. Suction is applied to empty the uterus.
  2. An instrument called a curette is inserted and scrapes the lining of the utuerus.
    ***Used up to 14-16 weeks
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44
Q

Surgical Abortions :Dilation and Evacuation (D&E)

A

After 14 weeks
Dilators
Suction Catheter
Possibly other instruments

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45
Q

Expected Side Effects

A
  • Bleeding
  • Cramping
  • Less frequent: Nausea, Vomiting, diarrhea, weakness
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46
Q

Complications of surgical abortions

A

Need for Aspiration (Medical): Aspiration (suction) is a procedure used in medical abortion and involves using suction to remove pregnancy tissue from the uterus. Sometimes, incomplete abortion might require an additional aspiration procedure to remove remaining tissue.

Uterine Perforation (Aspiration/D&E): During procedures like aspiration or dilation and evacuation (D&E), there is a slight risk of unintentional perforation of the uterine wall. This can happen if the instruments penetrate too deeply. If uterine perforation occurs, further medical attention might be required.

Cervical Laceration (Aspiration/D&E): During procedures involving dilation of the cervix (such as aspiration or D&E), there is a small risk of cervical laceration (tearing). This can occur if the cervix is not dilated properly or if instruments are inserted too forcefully.

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47
Q

Cervical insufficiency or Recurrent Premature Dilation of the Cervix

Cervical insufficiency, also known as recurrent premature dilation of the cervix, is a condition where the cervix begins to dilate and efface (thin out) prematurely during the second trimester of pregnancy, typically between 16 to 24 weeks. This can lead to preterm labor and delivery, often resulting in miscarriage or premature birth. Here’s more information about cervical insufficiency:

Symptoms and Diagnosis:

Cervical insufficiency is often characterized by passive and painless dilation of the cervix without contractions or significant discomfort.
It’s diagnosed based on a history of recurrent second-trimester pregnancy losses or preterm deliveries.
Risk Factors:

Women who have a history of cervical trauma (such as previous surgical procedures on the cervix) or structural abnormalities of the cervix might be at higher risk for cervical insufficiency.
Multiple miscarriages or preterm births can also be an indicator.
Management and Treatment:

A
  • Recurrent passive and painless dilation of the cervix during the 2nd Trimester. Doctors diagnose cervical insufficiency based on a person’s history of having multiple miscarriages or giving birth too early.
  • Dx based on history
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48
Q

Cervical insufficiency or Recurrent Premature Dilation of the Cervix. Risk Factors:

A

Congenital Risk Factors:

Presence of Bicornuate Uterus: A bicornuate uterus is a congenital condition where the uterus is divided into two distinct cavities. This structural abnormality can increase the risk of cervical insufficiency.
Exposure to DES (Diethylstilbestrol): DES is a synthetic estrogen that was given to some pregnant women between the 1940s and 1970s. Women exposed to DES in utero might be at increased risk of cervical insufficiency.
2. Acquired Risk Factors:

Multiple Gestation: Carrying more than one fetus (twins, triplets, etc.) can put extra pressure on the cervix and increase the risk of cervical insufficiency.
Infection: Certain infections can weaken the cervix and contribute to its premature dilation.
Trauma: Previous surgeries, procedures, or trauma to the cervix can weaken its structure and make it more prone to premature dilation.
3. Hormonal Risk Factors:

Relaxin Hormone: Relaxin is a hormone that helps soften and relax tissues in the body, including the cervix, during pregnancy. High levels of relaxin might contribute to cervical insufficiency.

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49
Q

Management: Medical . Cervical insufficiency or Recurrent Premature Dilation of the Cervix

A
  1. Bedrest:

Bedrest involves limiting physical activity and spending more time resting in a horizontal position.
The goal is to reduce pressure on the cervix and minimize the risk of further dilation.
2. Pelvic Rest:

Pelvic rest means avoiding sexual intercourse and refraining from any activities that could put stress on the pelvic area.
This approach aims to reduce the risk of irritation or additional strain on the cervix.
3. Anti-Inflammatory Medications:

Anti-inflammatory medications might be prescribed to manage any inflammation or discomfort that might be contributing to cervical changes.
These medications can help alleviate symptoms and support the cervix’s stability.
4. Progesterone:

Progesterone supplementation might be recommended to help maintain the integrity of the cervix and prevent further dilation.
Progesterone is a hormone that plays a crucial role in supporting pregnancy and maintaining the uterine environment.

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50
Q

Management: Surgical

A
  1. Cerclage:

Cerclage is a surgical procedure in which a stitch or suture is placed around the cervix to provide additional support and prevent it from dilating prematurely.
Cerclage can be used as a prophylactic (preventive) measure or as an emergency intervention if cervical changes are detected.
2. Prophylactic Cerclage (11-15 weeks):

A prophylactic cerclage is placed during pregnancy, typically between 11 and 15 weeks of gestation, to prevent cervical insufficiency and premature dilation.
This procedure is considered for individuals with a history of cervical insufficiency or structural issues that increase the risk.
3. Risks of Cerclage:

—–Preterm Labor (PTL): In some cases, cerclage might lead to contractions and preterm labor.
—–Preterm Premature Rupture of Membranes (PPROM): There’s a risk of the amniotic sac breaking too early.
—–Chorioamnionitis: This is an infection of the fetal membranes and amniotic fluid, which can lead to inflammation and complications.

51
Q

Nursing Care: Abortions

A

Nursing Care:

Observe for Contractions (CTX): Monitor the patient for any signs of contractions, as these could indicate preterm labor or other issues.
Observe for PPROM (Preterm Premature Rupture of Membranes): Keep an eye out for any sudden rupture of the amniotic sac before full term, as this can lead to preterm labor.
Observe for Signs and Symptoms of Infection: Watch for any signs of infection, such as fever, chills, abnormal vaginal discharge, or pain. Infection during pregnancy can be dangerous for both the mother and the fetus.
Education:

Activity Restrictions: Educate the patient about the importance of following activity restrictions, especially if they are at risk of preterm labor. This might involve limiting physical activity and avoiding heavy lifting or strenuous tasks.
Tocolytics: Tocolytics are medications used to suppress contractions and delay preterm labor. Provide information about tocolytics, their purpose, and potential side effects.
Signs and Symptoms to Report: Teach the patient about the specific signs and symptoms they should report to their healthcare provider immediately. These might include contractions, sudden gush of fluid, bleeding, or any unusual symptoms.

Tocolytics etymology

ChatGPT
The term “tocolytic” is derived from the Greek words “tokos,” meaning childbirth or labor, and “lysis,” meaning dissolution or loosening. Therefore, “tocolytic” literally means “dissolving labor” or “loosening childbirth.” Tocolytics are medications used to inhibit or suppress uterine contractions and delay the onset of labor, particularly in cases of preterm labor. The term reflects the action of these medications in preventing or delaying the process of childbirth by relaxing the uterine muscles.

52
Q

ECTOPIC PREGNANCY
خارج الرحم

ectopic etymology

The term “ectopic” comes from the Greek word “ektópos,” where “ek” means “out of” or “outside,” and “tópos” means “place.

A

A pregnancy that occurs outside the womb (uterus).

53
Q

Sites of implantation of ectopic pregnancies

A

slide 64

54
Q

ECTOPIC PREGNANCY Risk Factors:

A

History of STI or Pelvic Inflammatory Disease (PID): Sexually transmitted infections (STIs) and PID can cause inflammation and scarring in the reproductive organs, including the fallopian tubes. This scarring can disrupt the normal movement of the fertilized egg through the tubes, increasing the likelihood of ectopic pregnancy.

Previous Ectopic Pregnancy: If a person has already experienced an ectopic pregnancy, their risk of having another one in the future is increased. The scarring and damage caused by the initial ectopic pregnancy can affect the structure of the fallopian tubes, making it more difficult for a fertilized egg to travel to the uterus.

Endometriosis: Endometriosis is a condition in which tissue similar to the lining of the uterus grows outside the uterus. This tissue can affect the function of the fallopian tubes and increase the risk of ectopic pregnancy.

Intrauterine Devices (IUDs): While modern IUDs are highly effective contraceptive methods, there is a slight risk of ectopic pregnancy if a pregnancy occurs while an IUD is in place. The IUD can prevent the fertilized egg from entering the uterus and lead to implantation outside the uterus.

Assisted Reproductive Technologies: Procedures like in vitro fertilization (IVF) involve fertilizing eggs outside the body and then transferring the resulting embryos into the uterus. However, in some cases, the embryos might implant outside the uterus, leading to an ectopic pregnancy. This is partly due to the potential difficulty in ensuring proper embryo placement during IVF.

55
Q

ECTOPIC PREGNANCY Symptoms:

A

Missed Period: Not having a regular menstrual period when expected is a common early sign of pregnancy, including ectopic pregnancy.

Tenderness: Women might experience tenderness in the abdominal or pelvic region, often on the side where the ectopic pregnancy is occurring.

Pain: Persistent abdominal or pelvic pain is a significant symptom. This pain might be mild at first but can become severe and sharp.

Shoulder Pain: Internal bleeding caused by a ruptured ectopic pregnancy can irritate the diaphragm, leading to shoulder pain, which is a distinctive symptom.

Vaginal Bleeding: Light to heavy vaginal bleeding, often accompanied by abdominal pain, can occur due to the disruption of the ectopic pregnancy. Referred pain.

Shock: In severe cases of rupture, internal bleeding can lead to shock, characterized by rapid heartbeat, dizziness, confusion, and pale skin. Yes, you’re correct. Shock is indeed characterized by a significant drop in blood pressure (BP).

56
Q

ECTOPIC PREGNANCY Management:

salpingectomy etymology

The term “salpingectomy” is derived from two Greek words: “salpinx” and “ektomē.” Here’s the breakdown of the etymology:

Salpinx: The word “salpinx” (σάλπιγξ) in Greek refers to a trumpet or a tube-like structure. In medical terminology, it specifically refers to the fallopian tubes, which are tube-like structures that connect the ovaries to the uterus in the female reproductive system.

Ektomē: The word “ektomē” (ἐκτομή) in Greek means “excision” or “cutting out.” It’s derived from the verb “ektemnō,” which means “to cut out” or “to excise.

hCG stands for “human chorionic gonadotropin.” It is a hormone that is produced by the placenta shortly after a fertilized egg attaches to the uterine lining. hCG is often referred to as the “pregnancy hormone”

A

Methotrexate: Methotrexate is a medication that stops the growth of rapidly dividing cells, including the rapidly growing cells of an ectopic pregnancy. It’s often used when the ectopic pregnancy is detected early, the patient’s condition is stable, and the pregnancy hasn’t progressed significantly. Methotrexate is usually given by injection, and the patient’s hCG levels (a hormone produced during pregnancy) are monitored to ensure the treatment is effective. This method aims to dissolve the ectopic pregnancy without the need for surgery, thus preserving the fallopian tube.

Emergency Surgery (Salpingectomy): In cases where the ectopic pregnancy has caused severe bleeding, the fallopian tube has ruptured, or other complications are present, emergency surgery might be necessary. A salpingectomy involves the surgical removal of the affected fallopian tube. This is a definitive treatment that stops the source of bleeding and removes the ectopic pregnancy.

Attempt to Preserve Tube: If the ectopic pregnancy is detected early and hasn’t caused significant damage to the fallopian tube, a surgical procedure called salpingostomy might be performed. This involves making a small incision in the fallopian tube and removing the ectopic pregnancy while attempting to preserve the tube’s integrity. The success of this procedure depends on various factors, including the extent of damage to the tube.

Serial hCG Levels (3-6 weeks): Serial monitoring of hCG levels is an essential part of ectopic pregnancy management, regardless of the chosen treatment approach. hCG levels are checked over a period of time to ensure that the treatment is successful and that the pregnancy has been resolved. A declining trend in hCG levels indicates a positive response to treatment, while plateauing or rising levels might indicate a persistent or growing ectopic pregnancy.

57
Q

GESTATIONAL TROPHOBLASTIC DISEASE

Gestational trophoblastic disease (GTD) is a group of rare tumors that involve abnormal growth of the trophoblast, the outer layer of cells that typically develops and becomes the placenta during pregnancy.

The term “trophoblast” comes from two Greek words: “trophē,” meaning nourishment, and “blastos,” meaning germ or bud.

The trophoblast is the outermost layer of cells in the early embryo that plays a critical role in implantation, nutrient absorption, and ultimately gives rise to the placenta during pregnancy.

A

Hydatidiform Mole aka Molar Pregnancy: This is a noncancerous tumor that forms in the uterus as a result of an abnormal fertilization process. It usually appears as a cluster of fluid-filled sacs and may not develop into a viable embryo. There are two main types of hydatidiform moles: complete and partial.

Invasive Mole: An invasive mole is a molar pregnancy that has invaded into the uterine wall and can continue to grow and spread locally. Although it is not considered cancer, it can behave invasively and may require treatment to prevent complications.

Choriocarcinoma: Choriocarcinoma is a malignant cancer that develops from the trophoblast cells. It can occur after any type of pregnancy, including normal pregnancies, molar pregnancies, and even after a miscarriage or abortion. Choriocarcinoma is highly aggressive and has the potential to spread to other parts of the body.

Placental Site Trophoblastic Tumor: This is a rare form of GTD that arises from the intermediate trophoblast cells, which are a different subset of cells within the trophoblast layer. Placental site trophoblastic tumors are less aggressive than choriocarcinomas, but they can still invade the uterine wall and surrounding tissues.

Gestational trophoblastic disease often presents with abnormal vaginal bleeding, elevated levels of human chorionic gonadotropin (hCG) hormone, and other symptoms. Treatment depends on the type and extent of the disease. In most cases, surgical removal of the tumor is necessary, and additional therapies such as chemotherapy may be required for certain aggressive forms like choriocarcinoma.

58
Q

Includes Hydatidiform aka Molar Pregnancy

A

Both terms describe a specific type of abnormal pregnancy in which there is an overgrowth of trophoblast cells, leading to the formation of a mass of cystic tissue in the uterus. This tissue does not develop into a normal fetus but instead resembles a cluster of fluid-filled sacs, often resembling the appearance of a bunch of grapes.

59
Q

Hydatidiform Mole. is a type of gestational trophoblastic disease (GTD) that can occur during pregnancy.

A

Complete Hydatidiform Mole:
In a complete mole, an egg with no genetic information (no nucleus) is fertilized by a single sperm, or the genetic material of the sperm duplicates itself. This results in a pregnancy with no normal fetal development. The trophoblast cells proliferate abnormally and form a mass of fluid-filled sacs that resembles a bunch of grapes. A complete mole typically lacks fetal tissue and has a complete absence of normal genetic material.

Partial Hydatidiform Mole:
In a partial mole, a normal egg is fertilized by two sperm, resulting in an abnormal number of chromosomes in the embryo. This leads to the development of some fetal tissue mixed with abnormal placental tissue. The placenta in a partial mole is typically larger than normal and may have cystic areas. Unlike a complete mole, a partial mole has some fetal tissue, although it is usually not viable.

60
Q

Hydatidiform Mole
SYMPTOMS:

A

Second Trimester Vaginal Bleeding (dark brown or red): Vaginal bleeding is a common symptom of a molar pregnancy. The bleeding may be dark brown or red and can vary in severity. It’s often an abnormal bleeding pattern that prompts women to seek medical attention.

Uterus Larger than Dates: The uterus might appear larger than expected for the stage of pregnancy. This is due to the abnormal growth of trophoblast cells in the molar pregnancy.

Elevated hCG Levels: Molar pregnancies are often associated with high levels of human chorionic gonadotropin (hCG) hormone. hCG levels might be significantly higher than expected for the stage of pregnancy.

Hyperemesis: Hyperemesis gravidarum is severe nausea and vomiting during pregnancy. While it can be more common in molar pregnancies due to the higher hCG levels, it’s not specific to molar pregnancies and can occur in normal pregnancies as well.

Cramping: Cramping or abdominal pain can be a symptom of a molar pregnancy, but it’s also a symptom of various other conditions during pregnancy.

Preeclampsia: Preeclampsia is a serious pregnancy complication characterized by high blood pressure and damage to organs such as the liver and kidneys. While preeclampsia can occur in pregnancy, including molar pregnancies, it’s not a specific symptom of a molar pregnancy.

61
Q

Hydatidiform Mole
CARE:

A

Initial Management:

SAB (Spontaneous Abortion) if Needed: If the diagnosis is confirmed and the molar pregnancy is not spontaneously resolving, a medical procedure such as suction aspiration (D&C - Dilatation and Curettage) or dilation and evacuation (D&E) might be performed to remove the molar tissue from the uterus.
Risk of Choriocarcinoma:

A molar pregnancy carries a risk of developing choriocarcinoma, a malignant form of gestational trophoblastic disease. Therefore, careful monitoring is crucial.
Follow-Up and Monitoring:

Monthly Follow-Up: Patients diagnosed with a hydatidiform mole should have regular monthly follow-up appointments with their healthcare provider to monitor their condition and assess for any signs of complications.

Serial hCG Monitoring: The levels of human chorionic gonadotropin (hCG) hormone should be monitored closely.

Every 1-2 Weeks Until Undetectable: Initially, hCG levels are monitored every 1-2 weeks until hCG is undetectable on two separate blood tests. This indicates that the molar tissue has been successfully removed and is no longer producing hCG.
Every 1-2 Months for at Least a Year: After hCG becomes undetectable, regular monitoring continues with hCG tests every 1-2 months for at least a year to ensure that there are no signs of recurrence.
No Pregnancy:

Patients are usually advised to avoid getting pregnant during the follow-up period to allow for close monitoring and to reduce the risk of complications.

62
Q

HYPEREMESIS GRAVIDARUM

A

Prevalence of Nausea and Vomiting (N/V) in Pregnancy:

About 70% of pregnant women will experience some degree of nausea and vomiting during their pregnancy, often referred to as “morning sickness.” This is generally mild and doesn’t usually require medical intervention.
Development of Severe Nausea and Vomiting:

Approximately 3% of pregnant women will develop a more severe form of nausea and vomiting known as hyperemesis gravidarum.
Hospitalization for Severe Nausea and Vomiting:

Among those experiencing hyperemesis gravidarum, about 1-5% will have symptoms so severe that they require hospitalization for proper management and treatment.
Etiology of Hyperemesis Gravidarum:

The exact cause of hyperemesis gravidarum is not fully understood. There are various theories, but no single factor has been definitively identified.
Hormonal Changes: It’s thought that high levels of certain hormones, such as estrogen, progesterone, and human chorionic gonadotropin (hCG), which are all elevated during pregnancy, could contribute to the development of hyperemesis gravidarum.
Other Factors: Factors such as genetics, nutritional status, and psychological factors may also play a role.

63
Q

HYPEREMESIS GRAVIDARUM. Is a Dx of exclusion.

A

Diagnosis of Exclusion:

Hyperemesis gravidarum is often diagnosed through a process of exclusion. This means that other potential causes of persistent vomiting and nausea must be ruled out before hyperemesis gravidarum is confirmed as the diagnosis.
Criteria for Diagnosis:

Persistent Vomiting: Hyperemesis gravidarum is characterized by severe and persistent vomiting that is not attributed to other known causes.
Acute Starvation (Ketonuria): Ketonuria refers to the presence of ketones in the urine, which is a sign of the body using stored fat as an energy source due to a lack of adequate food intake. Presence of ketonuria can be used as a measure of acute starvation, which can occur due to severe vomiting and lack of food intake.
Excessive Nausea and Vomiting and Weight Loss: Diagnosis may also involve assessing the degree of excessive nausea and vomiting, as well as significant weight loss. In particular, a weight loss greater than 5% of the pre-pregnant weight is often considered a significant criterion for hyperemesis gravidarum

64
Q

HYPEREMESIS GRAVIDARUMRisk Factors:

A

Hyperthyroid Disorders: Conditions that cause an overactive thyroid (hyperthyroidism) can contribute to an increased risk of experiencing hyperemesis gravidarum. The hormonal imbalances associated with hyperthyroidism can impact various bodily functions, including the digestive system.

Molar Pregnancy: A molar pregnancy (hydatidiform mole) is a risk factor for hyperemesis gravidarum. The abnormal trophoblast growth associated with molar pregnancies can lead to hormonal imbalances that may contribute to severe nausea and vomiting.

Multiple Gestation: Carrying twins, triplets, or higher-order multiples (multiple gestation) increases the demand on the body and can lead to elevated levels of hormones, potentially increasing the risk of hyperemesis gravidarum.

Diabetes Mellitus (DM): Women with preexisting diabetes, especially poorly controlled diabetes, may have an increased risk of experiencing hyperemesis gravidarum due to the complex hormonal and metabolic changes that occur during pregnancy.

Gastrointestinal (GI) Disorders: Individuals with preexisting gastrointestinal disorders or conditions that affect digestion and nutrient absorption might be more susceptible to hyperemesis gravidarum due to the potential interaction between the disorder and the physiological changes of pregnancy.

Previous Pregnancy: A history of experiencing hyperemesis gravidarum in a previous pregnancy can increase the likelihood of having it in subsequent pregnancies. There might be underlying genetic or physiological factors that contribute to its recurrence.

65
Q

HYPEREMESIS GRAVIDARUMInitial Assessment:
(rule out)
As we said it is done by elimination

A

R/O Other Causes: (rule out)
When a pregnant individual presents with severe nausea and vomiting, especially if it occurs for the first time after nine weeks of gestation, it’s crucial to rule out other possible causes before diagnosing hyperemesis gravidarum.
Possible Differential Diagnoses:
There are several medical conditions that can cause symptoms of nausea and vomiting similar to hyperemesis gravidarum. These conditions should be considered and ruled out during the assessment:
Gastroenteritis: Inflammation of the stomach and intestines, often caused by viral or bacterial infections.
Pyelonephritis: Infection of the kidneys, which can cause abdominal pain and nausea.
Pancreatitis: Inflammation of the pancreas, which can lead to severe abdominal pain, nausea, and vomiting.
Cholecystitis: Inflammation of the gallbladder, which can cause pain, nausea, and vomiting.
Hepatitis: Inflammation of the liver, which can be associated with nausea and vomiting.
Thyroid Disorders: Thyroid dysfunction, such as hyperthyroidism, can lead to gastrointestinal symptoms including nausea and vomiting.

66
Q

HYPEREMESIS GRAVIDARUMInitial Assessment: continues ….. This is for someone suspected of having it

A

Assess for Dehydration:

Hypotension: Low blood pressure can be a sign of dehydration. Due to throwing up all the time . Monitoring blood pressure is important to assess the patient’s hydration status.
Intake and Output: Tracking fluid intake and urine output helps determine the balance and adequacy of hydration.
Urine Specific Gravity: Measuring the specific gravity of urine can provide information about the concentration of the urine, which can indicate dehydration.
Skin Turgor and Mucous Membranes: Assessing skin elasticity (turgor) and the moisture level of mucous membranes can provide additional indicators of dehydration.
Electrolyte Imbalance: Dehydration can lead to electrolyte imbalances. Monitoring laboratory values and assessing signs and symptoms of specific electrolyte deficiencies, such as hypokalemia (low potassium), is important.
Vitamin Deficiencies:

Vitamin B1, B6, and B12 Deficiencies: Severe and prolonged vomiting can lead to deficiencies in essential vitamins, which can have serious consequences. Vitamin B1 deficiency, for example, can result in Wernicke-Korsakoff syndrome, a neurological disorder.
IV Fluids and Electrolyte Replacement:

Administering intravenous (IV) fluids is often necessary to correct dehydration and electrolyte imbalances. Electrolytes like potassium, sodium, and others may need to be replaced to ensure proper bodily functions.
NPO (Nothing by Mouth):

To give the stomach and digestive system a rest, individuals with hyperemesis gravidarum might be advised to avoid oral intake of food and fluids for a period of time.

67
Q

HYPEREMESIS GRAVIDARUMNursing Care:

A

Anti-emetics (Anti-Nausea Medications):

Pyridoxine (B6)/Doxylamine: A combination of vitamin B6 (pyridoxine) and doxylamine is commonly used to alleviate nausea and vomiting during pregnancy.
Phenergan: Phenergan (promethazine) is an anti-emetic medication that can help control nausea and vomiting.
Reglan: Reglan (metoclopramide) is used to relieve symptoms of nausea and improve gastric emptying.
Compazine: Compazine (prochlorperazine) is another anti-emetic medication that can be effective in managing nausea and vomiting.
Zofran: Zofran (ondansetron) is often used to control nausea and vomiting, particularly in cases of severe vomiting.
Chlorpromazine: Chlorpromazine is an antipsychotic medication that can also be used as an anti-emetic in certain cases.
Steroids: In some cases of hyperemesis gravidarum, steroids might be prescribed to help control severe symptoms.
Small Frequent Meals:

Encouraging small, frequent meals instead of large, heavy meals can help manage nausea. An empty stomach can often exacerbate feelings of nausea, so maintaining a constant intake of small amounts of food might be more tolerable.

68
Q

HYPERTENSIVE DISORDERS IN PREGNANCY

A

Prevalence: Hypertensive disorders in pregnancy are relatively common, occurring in approximately 5-10% of all pregnancies. These disorders involve high blood pressure (hypertension) and can have various implications for both the pregnant individual and the developing fetus.

Leading Cause of Maternal Death: Hypertensive disorders in pregnancy are a significant concern due to their potential complications. They are considered a leading cause of maternal mortality, emphasizing the importance of proper management and monitoring to ensure the health and safety of pregnant individuals.

Hypertensive disorders in pregnancy encompass a range of conditions, including gestational hypertension, preeclampsia, eclampsia, and chronic hypertension

69
Q

Hypertensive disorders that can occur around the 20-week mark of pregnancy.’

The acronym “HELLP” stands for “Hemolysis, Elevated Liver Enzymes, Low Platelets

A

Gestational Hypertension: High blood pressure (hypertension) that develops after the 20th week of pregnancy. It’s characterized by elevated blood pressure without the presence of proteinuria (excessive protein in the urine), a key marker of pre-eclampsia.

Pre-eclampsia: A more severe condition that typically arises after the 20th week of pregnancy. It’s characterized by high blood pressure and proteinuria. Pre-eclampsia can affect various organs and systems, and it’s important to manage it to prevent complications.

Eclampsia: A serious progression of pre-eclampsia characterized by the onset of seizures or convulsions. Eclampsia is a medical emergency that requires immediate attention and intervention.

cHTN with Superimposed Pre-eclampsia: Refers to individuals with chronic hypertension (pre-existing high blood pressure) who develop pre-eclampsia during pregnancy. This combination requires careful monitoring and management due to the risks associated with both conditions.

cHTN with Superimposed Eclampsia: Similar to the previous point, this term refers to those with chronic hypertension who develop eclampsia during pregnancy, which involves seizures.

HELLP Syndrome: A serious condition that can occur alongside pre-eclampsia. It involves hemolysis (breakdown of red blood cells), elevated liver enzymes, and low platelet count. HELLP syndrome requires close monitoring and often necessitates medical intervention

70
Q

Risk Factors for HYPERTENSIVE DISORDERS IN PREGNANCY

A

First pregnancy
Family history
Obesity
Multiple gestations
Hx of Pre-eclampsia
Hx of poor pregnancy outcome: IUGR (Intrauterine Growth Restriction): IUGR occurs when a baby fails to reach its expected growth potential while in the womb. This can result in a baby being smaller than expected for its gestational age. IUGR can be caused by various factors, including placental problems, maternal health conditions, and certain genetic factors.

Placental Abruption: Placental abruption is a serious condition where the placenta detaches from the uterine wall before the baby is born. This can lead to bleeding, decreased oxygen supply to the baby, and other complications. It can be life-threatening for both the mother and the baby.

IUFD (Intrauterine Fetal Demise): IUFD refers to the unfortunate event of a baby passing away inside the womb before birth. This can occur for various reasons, including genetic factors, placental problems, infections, and maternal health conditions.

-Pre-existing diabetes, HTN, or renal disease
Gestational diabetes

71
Q

NORMAL FINDINGS IN PREGNANCY

A

Blood: During pregnancy, the volume of blood in the body increases to support the needs of both the pregnant individual and the developing fetus. This increase in blood volume helps supply oxygen and nutrients to the growing baby.

Plasma Volume (50%): Plasma, the liquid component of blood, also increases during pregnancy. This is a part of the overall increase in blood volume. The increased plasma volume helps maintain blood pressure and support the increased metabolic demands of pregnancy.

Cardiac Output: Cardiac output, the amount of blood pumped by the heart per minute, increases during pregnancy. This is to ensure that an adequate supply of oxygen-rich blood is delivered to the placenta and the developing fetus.

Lower Blood Pressure (until 3rd Trimester): In the early stages of pregnancy, blood pressure often decreases due to changes in blood vessel tone and increased blood volume. This can result in slightly lower blood pressure, particularly during the first and second trimesters.

Lower Total Peripheral Resistance: Total peripheral resistance (TPR) refers to the resistance the blood encounters as it flows through the blood vessels. During pregnancy, TPR decreases, allowing blood to flow more easily through the body. This change helps support the increased cardiac output and blood flow needed for the developing baby.

72
Q

FINDINGS IN PRE-ECLAMPSIA

A

Little or No Change in Blood and Plasma Volume: Unlike the normal increase in blood and plasma volume during pregnancy, individuals with pre-eclampsia often experience little to no change in these volumes. However the bP goes up due to the vessels narrowing too much and working in weird ways coz they are fucked up.

Variable Cardiac Output: Cardiac output, the amount of blood pumped by the heart per minute, can vary in pre-eclampsia. This variability is due to the complex interactions between blood vessels, the heart, and the placenta. It’s important to note that cardiac output might not increase as expected during pregnancy in individuals with pre-eclampsia.

Increased Blood Pressure (+ BP): One of the defining features of pre-eclampsia is high blood pressure (hypertension). Individuals with pre-eclampsia often experience a significant increase in blood pressure. This elevation in blood pressure is a key diagnostic criterion for the condition.

Increased Total Peripheral Resistance (+ Total Peripheral Resistance): Total peripheral resistance (TPR) refers to the resistance that blood encounters as it flows through the blood vessels. In pre-eclampsia, TPR is often increased, meaning that blood vessels are constricted and resistant to blood flow. This can contribute to the elevated blood pressure observed in pre-eclampsia.

73
Q

Factoid

A

Preeclampsia is a major contributor of maternal and neonatal mortality. It is the second largest cause of maternal mortality worldwide and affects 5%-7% of pregnancies worldwide.

74
Q

Pregnant Woman at 32 weeks of gestation with indications of potential pre-eclampsia.

A

The provided information outlines a case involving a pregnant individual at 32 weeks of gestation with indications of potential pre-eclampsia. Let’s break down the details:

Gestation and Hypertension: The patient is at 32 weeks of gestation (around 8 months pregnant) and has no documented history of hypertension before this pregnancy.

Blood Pressure (B/P): The initial blood pressure (admission) was 142/94 mm Hg. However, the subsequent blood pressures were elevated: 160/112 mm Hg recorded twice. Elevated blood pressure is a key characteristic of pre-eclampsia.

Protein in Urine (PCR Protein): There is a presence of protein in the urine, indicated by a measurement of 0.5 PCR. The presence of proteinuria is another significant marker of pre-eclampsia.

Symptoms:

Headache: The patient is experiencing a severe headache rated at 8 out of 10. Headaches are common symptoms of pre-eclampsia.
URQ Pain: The patient reports upper right quadrant (URQ) pain with a rating of 6 out of 10. Pain in this area can be associated with liver involvement in pre-eclampsia.
Patient History: The patient has a history of being gravida 2 (G2), which means this is their second pregnancy, and para 1 (P1), meaning they have given birth to one child previously. The patient has a previous diagnosis of pre-eclampsia, indicating a potential recurrence of the condition.

75
Q

check slide 85-86 make sure you know it

A
76
Q

Nursing Care with Magnesium Sulfate. Bolus:

Seizure Prevention: Magnesium sulfate is used to prevent seizures in pre-eclampsia, a condition that can lead to eclampsia with seizures. It acts as a central nervous system depressant, stabilizing nerve and muscle cell excitability, reducing the risk of eclamptic seizures.
Vasodilation: Magnesium sulfate relaxes and dilates blood vessels, countering high blood pressure caused by constricted vessels in pre-eclampsia. This improves blood flow, benefiting both the pregnant individual and the fetus.
Neuroprotection: In cases of preterm birth and pre-eclampsia, magnesium sulfate protects the fetal brain development. It helps reduce the risk of neurological complications in premature babies.
Smooth Muscle Relaxation: Magnesium sulfate affects uterine smooth muscles, preventing contractions and premature labor. This is crucial in severe pre-eclampsia to prevent premature delivery.
Cardiovascular Stability: Magnesium sulfate reduces blood pressure and stabilizes cardiac function, ensuring overall cardiovascular stability. This is important in pre-eclampsia where the cardiovascular system can be compromised.

A

magnesium sulfate, often used to manage pre-eclampsia and prevent eclamptic seizures during pregnancy. Let’s break down the steps:

Duo Check of Dosing Before Administration: This step emphasizes the importance of double-checking the dosage of magnesium sulfate before administration. Ensuring accuracy in medication dosage is critical for patient safety.

Baseline Assessment: Vital Signs (V.S.), Severe Features, and Electronic Fetal Monitoring (EFM): Before administering magnesium sulfate, baseline assessments are conducted. This includes checking the patient’s vital signs (blood pressure, heart rate, respiratory rate, temperature), assessing for any severe features of pre-eclampsia, and monitoring the fetal heart rate using electronic fetal monitoring.

Bolus Administration: The initial administration involves giving 4-6 grams of magnesium sulfate intravenously (IV) over 20 minutes. If the patient’s Body Mass Index (BMI) is greater than 35, a higher dose of 6 grams is used.

Vital Sign Monitoring: After the bolus administration, the patient’s vital signs are monitored closely. Vital signs are checked every 5 minutes to observe for any changes or potential adverse effects related to the medication.

77
Q

Nursing Care with Magnesium Sulfate- Maintenance Infusion

DTRs Assessment:

Before initiating magnesium sulfate therapy, baseline DTRs should be assessed for the patient. This provides a reference point for monitoring changes during treatment.
Throughout the course of magnesium sulfate infusion, DTRs should be regularly monitored. Changes in DTRs can indicate magnesium toxicity.
Diminished or absent DTRs could suggest an excessive magnesium level in the body, which might require adjusting the dosage or discontinuing the infusion.
Clonus Assessment:

Clonus, as mentioned earlier, involves involuntary muscle contractions. In the context of magnesium sulfate therapy, clonus is particularly important to assess because it can indicate an increased risk of seizures.
Hyperactive clonus, particularly sustained clonus, can be a sign of magnesium toxicity and an impending seizure.
Healthcare providers should monitor for the presence of clonus, particularly in the ankles, and be vigilant for any changes.

A
  • Duo check of dosing before administration.
  • 1 gm/hr. IV
  • V.S. every 1 hour for 8 hours.
    DTR’s, clonus, lung sounds, & LOC with V.S.
78
Q

Nursing Care with Magnesium Sulfate. Other Nursing Care

A

Vital Signs Monitoring: Regular monitoring of vital signs, including blood pressure, heart rate, and respiratory rate, is essential. Magnesium sulfate can affect cardiovascular function, so it’s important to track these parameters closely.

Deep Tendon Reflex Monitoring: Since magnesium sulfate can depress deep tendon reflexes, regular monitoring of reflexes (such as the patellar reflex) is necessary to detect any changes.

Respiratory Rate Monitoring: Magnesium sulfate can lead to respiratory depression in high doses. Monitoring the patient’s respiratory rate and depth is crucial to catch any signs of respiratory distress.

Laboratory Tests: Periodic monitoring of serum magnesium levels is necessary to ensure that the therapeutic range is maintained and to prevent magnesium toxicity.

Calcium Gluconate Availability: Calcium gluconate is the antidote for magnesium sulfate toxicity. Nurses should have it readily available in case magnesium toxicity occurs.

Patient Positioning: Patients receiving magnesium sulfate may be at risk for orthostatic hypotension due to its vasodilatory effects. Proper positioning, such as slowly transitioning from lying down to sitting and then standing, can help prevent falls.

Skin Integrity: Patients on prolonged bedrest are at risk for pressure ulcers. Frequent repositioning, adequate padding, and skin assessment are vital to prevent skin breakdown.

Fluid and Electrolyte Balance: Magnesium sulfate can affect electrolyte balance, particularly calcium and potassium levels. Monitoring these levels and ensuring proper hydration is important.

Medication Administration: Administering magnesium sulfate requires careful attention to the rate of infusion and the patient’s response. Nurses should follow the healthcare provider’s orders and adjust the infusion rate as needed.

Patient Education: Educate the patient and their family about the purpose of magnesium sulfate, its potential side effects, and the importance of adhering to the prescribed treatment plan.

Fall Precautions: Given the risk of dizziness or weakness associated with magnesium sulfate, implementing fall precautions (e.g., call bell within reach, non-slip footwear) is important to ensure patient safety.

Pregnancy Considerations: If magnesium sulfate is being used for preeclampsia or preterm labor, monitoring fetal heart rate and uterine contractions is crucial.

Documentation: Thorough and accurate documentation of medication administration, vital signs, neurological assessments, and patient response is essential for continuity of care.

79
Q

Lab draws Before Med administration

A

Magnesium Level: Checking the patient’s serum magnesium level before administering magnesium sulfate is crucial to determine the patient’s baseline magnesium status. This helps healthcare providers determine the appropriate dosage and monitor for potential toxicity. Magnesium levels outside the normal range can influence the dosage and infusion rate of magnesium sulfate.

Hepatic Panel: A hepatic panel, also known as a liver function test, measures the levels of various enzymes and proteins in the blood that are produced by the liver. Magnesium sulfate metabolism primarily occurs in the liver. If the patient has underlying liver dysfunction, their ability to metabolize and excrete magnesium sulfate could be compromised. Monitoring liver function helps ensure the medication’s safe administration.

CBC (Complete Blood Count): A CBC provides information about the patient’s red blood cells, white blood cells, and platelets. This information is important to assess the patient’s overall health status and any potential complications. For instance, if the patient has anemia or thrombocytopenia, healthcare providers might consider these factors when deciding on the appropriate magnesium sulfate dosage and monitoring plan.

80
Q

Lab draws. During IV Infusion

A

Magnesium Level at 30 Minutes: Checking the magnesium level shortly after starting the infusion helps healthcare providers assess how the patient’s body is responding to the initial dose. It allows them to gauge how quickly the magnesium level is rising and whether any immediate adjustments to the infusion rate are necessary.

Magnesium Level Every 6 Hours: Regular monitoring of magnesium levels is essential to maintain the therapeutic range and prevent magnesium toxicity. Magnesium levels should be monitored every 6 hours to ensure that the levels remain within the desired range. This helps healthcare providers adjust the infusion rate as needed to achieve the desired therapeutic effect.

CBC (Complete Blood Count) and Hepatic Panel Daily: Monitoring the CBC and hepatic panel daily provides valuable information about the patient’s overall health and how their body is responding to the magnesium sulfate infusion. Changes in blood cell counts and liver function could impact the patient’s ability to metabolize and excrete the medication. Additionally, daily monitoring helps identify any potential adverse effects or complications related to the infusion.

81
Q

Mag Blood Levels. Basically the further you go from the recommended dose of Serum Level: 5-8 mg/dL the worse the side effects and effects on the body

A

It appears you’ve provided a list of magnesium blood levels along with their associated effects. These levels are relevant when monitoring patients who are receiving magnesium sulfate infusions or treatment. Here’s a breakdown of the effects associated with different magnesium blood levels:

Serum Level: 5-8 mg/dL

Effects: Anticonvulsant prophylaxis (used to prevent seizures).
This range is commonly used for seizure prophylaxis in certain medical conditions, such as preeclampsia.
Serum Level: 5-10 mg/dL

Effects: Electrocardiographic changes.
Magnesium can impact heart rhythm and electrical activity, which may lead to changes on an electrocardiogram (ECG/EKG).
Serum Level: 8-12 mg/dL

Effects: Loss of deep tendon reflexes, somnolence (drowsiness), slurred speech.
Higher magnesium levels can lead to a decrease in deep tendon reflexes (hyporeflexia) and neurological symptoms such as drowsiness and slurred speech.
Serum Level: 10-12 mg/dL

Effects: Muscular paralysis, respiratory difficulty.
At these levels, magnesium can cause muscle weakness, potentially leading to paralysis. Respiratory muscles may also be affected, leading to difficulty in breathing.
Serum Level: 15-17 mg/dL

Effects: Cardiac arrest.
Elevated magnesium levels can have a depressant effect on the cardiovascular system, potentially leading to cardiac arrest.
Serum Level: 20-35 mg/dL

Effects: Cardiac arrest.
Extremely high magnesium levels can further increase the risk of cardiac arrest due to severe depression of cardiac function.

82
Q

Magnesium Sulfate. list of potential effects and considerations related to the administration of magnesium sulfate during labor induction or management

A
  1. Hypotonia and Uterine Contractions:
    Hypotonia refers to reduced muscle tone or decreased muscle contractions. When magnesium sulfate is administered during labor induction or to manage certain conditions, it can lead to hypotonia of the uterine muscles. This means that the uterine contractions necessary for labor progression might become weaker or less effective. To counteract this effect, healthcare providers might prepare for the possibility of using Pitocin (oxytocin) infusion. Pitocin is a medication that stimulates uterine contractions and is commonly used to augment or strengthen contractions during labor.
  2. Flushing:
    Flushing refers to a sensation of warmth, redness, and skin irritation that can occur when blood vessels in the skin dilate. This can be a side effect of magnesium sulfate administration. While flushing itself is usually harmless and temporary, it’s important to monitor the patient’s overall response to magnesium sulfate.
  3. Diarrhea:
    Diarrhea can be a gastrointestinal side effect of magnesium sulfate. This is due to its impact on smooth muscle relaxation, including the muscles in the digestive tract. Monitoring fluid balance and addressing dehydration, if it occurs, is important.
  4. Nausea and Vomiting (N/V):
    Nausea and vomiting are common side effects of magnesium sulfate. This can be managed with supportive care and adjustments in medication dosage, if necessary.
83
Q

Reminder

A

YOU ARE TAKING CARE OF 2 PATIENTS!
The neonate will experience some side effects from the magnesium infusion. Magnesium does cross the placental barrier. The neonate will experience some respiratory depression and hypotonia, causing decreased APGAR scores also. These side effects subside within 24 hours.

84
Q

Treatment/Nursing Care cHT and Pre-eclampsia without severe features (managed at home)

A

Self-Monitoring Instructions:

Teach the pregnant woman how to measure their blood pressure (BP) accurately using a home BP monitor.
Explain how to use urine dips to monitor for proteinuria (protein in the urine), which is a common sign of pre-eclampsia.
Educate them on performing kick counts to monitor fetal movements. Reduced fetal movements can be an indicator of fetal distress.
2. Recognizing Worsening Signs:

Inform the patient about signs and symptoms that may indicate worsening of their condition, such as severe headaches, visual disturbances, sudden weight gain, abdominal pain, or changes in fetal movement.
Stress the importance of contacting their healthcare provider immediately if they experience any of these signs.
3. Frequent Visits and Fetal Assessments:

Emphasize the need for regular prenatal visits to monitor both the pregnant individual’s health and the well-being of the fetus.
Explain the significance of fetal assessments, including ultrasounds and non-stress tests, to ensure the baby’s growth and development are on track.
4. Regular Diet:

Recommend a balanced and nutritious diet that meets the pregnant individual’s dietary needs.
Highlight the importance of consuming foods rich in essential nutrients, such as calcium, iron, and folic acid, to support both the mother and the baby.
5. Activity Restrictions:

Reinforce the need for activity restrictions, especially avoiding strenuous activities or heavy lifting.
Encourage them to prioritize rest and to listen to their body’s signals to avoid overexertion.

85
Q

HELLP SYNDROME

A

HELLP syndrome is a serious and potentially life-threatening condition that can occur during pregnancy. The acronym “HELLP” stands for its key characteristics: Hemolysis, Elevated Liver Enzymes, and Low Platelets. It’s closely associated with preeclampsia and can sometimes develop without prominent pre-eclamptic symptoms or with only mild symptoms. Here’s more information about HELLP syndrome:

  1. Hemolysis:
    Hemolysis refers to the breakdown of red blood cells. In HELLP syndrome, damaged red blood cells can lead to anemia (low red blood cell count) and related symptoms like fatigue, paleness, and jaundice (yellowing of the skin and eyes).
  2. Elevated Liver Enzymes:
    Elevated liver enzymes are indicative of liver damage or dysfunction. The liver plays a crucial role in filtering toxins from the blood and producing essential proteins. In HELLP syndrome, liver function can be impaired, leading to symptoms such as abdominal pain, nausea, vomiting, and jaundice.
  3. Low Platelets:
    Platelets are small blood cells that are essential for clotting and preventing excessive bleeding. In HELLP syndrome, platelet counts can drop significantly, which can result in bleeding tendencies, easy bruising, and a risk of bleeding complications.
86
Q

Placenta Previa

Placenta previa is a medical condition where the placenta is situated low in the uterus, near or covering the cervix (the opening of the uterus). The cervix is the pathway through which the baby exits the uterus during labor and delivery. Normally, the placenta is located higher up in the uterus, away from the cervix.

It comes out during birth before the baby instead of after.

A

Placenta previa is a pregnancy complication where the placenta partially or completely covers the cervix, the opening of the uterus. This can lead to bleeding, especially during the third trimester, and may necessitate special care and delivery planning.

Literal Meaning:
The term “placenta previa” originates from Latin and means “afterbirth first.” In this condition, the placenta is located near or over the cervical opening rather than in its typical upper position.

Prevalence:

Approximately 1 in 200 pregnancies is affected by placenta previa.
The chances of having placenta previa are higher in certain situations:
With the first pregnancy, the chance is about one in 400. (does this mean that it is less in the upcoming ones ?

Yes, generally speaking, the likelihood of experiencing placenta previa tends to be lower in subsequent pregnancies compared to the first pregnancy)
The risk increases with each cesarean section a woman has had.
- Chances with 1st pregnancy is one in
400
- With each cesarean section a woman has her chance increase dramatically.
- Educate

87
Q

Placental Abruption

A

Placental abruption, also known as abruptio placentae, is a serious pregnancy complication characterized by the premature separation of the placenta from the uterine wall after 20 weeks of gestation but before the baby is born. This condition can have significant implications for both the mother and the baby.

Key Points:

  1. Premature Separation:

Placental abruption involves the detachment of the placenta from its normal position on the uterine wall before delivery.
2. Timing:

Placental abruption typically occurs after 20 weeks of pregnancy. It can happen at any point from mid-pregnancy to labor.
- Occurs in 1% of all pregnancies
- 40% mortality rate for the fetus
- 5% maternal mortality rate

88
Q

Classification of Abruption

A
  • Grade 0- Dx made from observation of afterbirth
  • Grade 1- no vaginal bleeding, 10% separation, & blood loss < 500ml
  • Grade 2- none to moderate bleeding, 20-50% separation, & 1000 to 1500 ml blood loss
  • Grade 3- none to moderate bleeding, >50% separation, & >1500ml blood loss
89
Q

Management of placental abruption

A

Is guided by fetal well being.

The management of placental abruption is indeed guided by the well-being of both the mother and the fetus. Placental abruption is a serious and potentially life-threatening condition, and the primary goal of management is to ensure the safety of both the pregnant individual and the baby. Here’s an overview of how management is approached:

  1. Fetal Monitoring:

Continuous fetal monitoring is crucial to assess the baby’s heart rate and overall well-being.
Monitoring helps detect signs of fetal distress or oxygen deprivation, which can guide decision-making regarding the timing and method of delivery.
2. Maternal Stability:

The mother’s condition is closely monitored as well. This includes assessing her blood pressure, heart rate, and signs of shock or hemorrhage.
Stabilizing the mother’s condition is important to prevent complications and support the baby’s well-being.
3. Management Based on Severity:

The severity of the abruption determines the management approach. Mild abruptions might be managed conservatively, while severe abruptions often necessitate immediate delivery.
4. Delivery Planning:

If the baby’s well-being is compromised or if the mother’s condition is unstable, delivery might be necessary, often via cesarean section.
In less severe cases, the healthcare provider may choose to closely monitor both the mother and the baby and make decisions based on their responses to treatment.
5. Blood Transfusions:

Blood loss due to abruption can lead to anemia and shock. Blood transfusions might be necessary to restore blood volume and prevent complications.
6. Monitoring Coagulation:

Coagulation studies are done to assess the blood’s ability to clot. Abnormalities can be addressed with appropriate interventions.
7. Medications:

Medications to control blood pressure and prevent seizures might be administered, especially in cases of severe abruption.
8. Neonatal Care:

Babies born prematurely due to abruption might require specialized neonatal care.
9. Maternal and Fetal Monitoring After Delivery:

Close monitoring continues after delivery to address any ongoing bleeding or complications.

90
Q

Amniotic Fluid (1000ml normal) Polyhydraminos

A

Polyhydramnios is a condition during pregnancy characterized by an excessive accumulation of amniotic fluid in the amniotic sac surrounding the baby. Here’s a breakdown of the key points you’ve mentioned about polyhydramnios:

Amniotic Fluid Volume:

Normal amniotic fluid volume typically ranges around 800 to 1000 ml throughout pregnancy.
Polyhydramnios is diagnosed when the amniotic fluid volume exceeds 2000 ml.
Incidence and Timing:

Polyhydramnios occurs in approximately 2% of pregnancies.
The timeframe mentioned (32-36 weeks) indicates the gestational age range when polyhydramnios might be diagnosed.
Associated Factors:

Polyhydramnios can be associated with various conditions and factors, including:
Diabetes mellitus (DM)
Fetal anomalies or abnormalities
Conditions affecting fetal swallowing or fluid regulation
Potential Risks and Complications:

Polyhydramnios can increase the risk of several complications, including:
Preterm labor: Increased amniotic fluid can put pressure on the uterus and potentially trigger early contractions.
Preterm premature rupture of membranes (PPROM): The amniotic sac may rupture before term, leading to the premature release of amniotic fluid.
Premature rupture of membranes (PROM): Similar to PPROM, this involves the rupture of the amniotic sac before labor begins.
Management:

The management of polyhydramnios depends on its underlying cause, severity, and potential risks.
Close monitoring of the mother and baby’s health is essential.
If a specific cause is identified, addressing that cause may help manage polyhydramnios.
Fetal Well-Being:

Regular assessments of fetal well-being, including ultrasound and non-stress tests, are important to monitor the baby’s growth and health.

91
Q

Amniotic Fluid (1000ml normal). Oligohydraminos

so if there is not enough amiotic volume it means that the fetus’s kidneys are not working properly and therefore not producing enough urine ?

Yes, that’s correct. In cases of oligohydramnios (insufficient amniotic fluid volume), one possible contributing factor is that the fetus’s kidneys might not be functioning properly, leading to reduced urine production. The relationship between fetal kidney function and amniotic fluid volume is interconnected:

A

Oligohydramnios:

Oligohydramnios is a condition during pregnancy characterized by a lower-than-normal level of amniotic fluid in the amniotic sac surrounding the baby. Here’s a breakdown of the key points you’ve mentioned about oligohydramnios:

Amniotic Fluid Volume:

Normal amniotic fluid volume typically ranges around 800 to 1000 ml throughout pregnancy.
Oligohydramnios is diagnosed when the amniotic fluid volume is less than 500 ml.
Incidence and Timing:

Oligohydramnios occurs in approximately 4% of pregnancies.
The timeframe mentioned (32-36 weeks) indicates the gestational age range when oligohydramnios might be diagnosed.
Possible Causes:

Oligohydramnios can result from various factors, including:
Fetal kidney or urinary tract problems that lead to reduced urine production.
Conditions that restrict the baby’s ability to swallow and excrete amniotic fluid.
Potential Consequences:

Oligohydramnios can lead to a range of complications, including:
Impaired fetal lung development: Amniotic fluid helps the baby’s lungs grow and develop properly.
Fetal growth restriction: Insufficient fluid can affect the baby’s growth.
Fetal cord compression: Decreased fluid might increase the risk of the umbilical cord becoming compressed during labor, potentially affecting oxygen and nutrient supply to the baby. (This relationship is based on the understanding that amniotic fluid acts as a protective cushion around the fetus, helping to prevent the umbilical cord from being compressed or squeezed during movements)
Limb deformities: The baby’s movement in the amniotic fluid contributes to proper limb development. Reduced fluid can lead to deformities.
Management and Monitoring:

Management depends on the underlying cause, severity, and potential risks.
Fetal monitoring, including ultrasound and non-stress tests, helps assess the baby’s well-being.
Delivery Planning:

If oligohydramnios poses risks to the baby’s health, healthcare providers might consider delivery earlier than originally planned

92
Q

PPROM

A

Preterm Premature Rupture of Membranes

93
Q

Biophysical Profile (BPP)

so we use a doppler for some of them and ultrasound for others ? ultrasound for all

A

Fetal Breathing Movements (2 points):
This component evaluates the presence of rhythmic breathing movements performed by the fetus. The absence of these movements might indicate potential issues with the central nervous system or lung development.

Gross Body Movements (2 points):
Gross body movements refer to the large, coordinated movements of the fetus, such as stretching and turning. The observation of these movements is an indicator of the fetus’s neurological development and overall well-being.

Fetal Tone (2 points):
Fetal tone refers to the muscle tone or tension in the fetus’s limbs. The assessment involves observing the level of flexion and extension in the fetus’s arms and legs. Normal muscle tone is essential for proper development and mobility.

Reactive Heart Rate (Non-Stress Test - NST) (2 points):
The reactive NST involves monitoring the fetal heart rate in response to the baby’s movements. A reactive result, where the fetal heart rate accelerates in response to movement, is a positive sign of fetal well-being.

Qualitative Amniotic Fluid Volume (Amniotic Fluid Index - AFI) (2 points):
The AFI is a measurement of the amount of amniotic fluid surrounding the fetus. Amniotic fluid provides protection and space for the fetus to move. Adequate fluid volume is important for fetal development. Too much or too little amniotic fluid can indicate potential problems.

94
Q

Amniotic fluid, on the other hand, serves several other important functions:

A

Protection: Amniotic fluid acts as a cushion, protecting the fetus from physical impact and trauma.

Temperature Regulation: The amniotic fluid helps maintain a stable temperature around the fetus, ensuring that the environment remains optimal for growth and development.

Fetal Movement: The fluid allows the fetus to move and stretch its limbs, which is essential for healthy musculoskeletal development.

Lung Development: As the fetus swallows amniotic fluid, it helps the fetal lungs develop and mature. This is because the fluid contains substances that are important for lung growth.

Digestive Practice: Swallowing and digesting the amniotic fluid also allow the fetus to practice its digestive system, helping it prepare for feeding after birth.

95
Q

Placenta:
The placenta is an organ that develops during pregnancy and attaches to the inner wall of the uterus. It serves as a connection between the mother and the developing fetus. The placenta contains blood vessels that allow for the exchange of nutrients, oxygen, and waste products between the maternal bloodstream and the fetal bloodstream. It also produces hormones that are essential for maintaining pregnancy.

Amniotic Fluid:
Amniotic fluid is a clear, slightly yellowish fluid that surrounds and cushions the developing fetus within the amniotic sac. The amniotic sac is a membranous sac that encloses the fetus and is separate from the placenta. Amniotic fluid provides protection for the fetus, helps maintain a stable temperature, allows the fetus to move and grow, and assists in lung development as the fetus swallows and “breathes” the fluid.

A
96
Q

The placenta like the transition between the baby and the mom’s body?

A

Yes, you’re absolutely right.

The placenta serves as a vital connection and transition point between the developing baby and the mother’s body during pregnancy. It’s often referred to as the “life-support system” for the fetus. Here’s a closer look at the role of the placenta in connecting the baby and the mother:

Connection to the Uterus: The placenta develops within the uterus and is attached to the inner uterine wall. It’s connected to the fetus through the umbilical cord, which contains blood vessels that carry nutrients, oxygen, and waste products between the placenta and the baby.

Nutrient and Gas Exchange: The placenta allows for the exchange of nutrients, oxygen, and waste products between the maternal bloodstream and the fetal bloodstream. Oxygen and essential nutrients from the mother’s blood are transferred to the baby’s blood, while waste products from the baby’s metabolism are carried back to the mother’s bloodstream for elimination.

Hormone Production: The placenta produces hormones that are crucial for maintaining pregnancy and supporting fetal growth. Hormones such as human chorionic gonadotropin (hCG), estrogen, and progesterone are released by the placenta to help sustain the pregnancy and create a suitable environment for fetal development.

Barrier and Filter: While the placenta allows for the exchange of substances between the mother and the fetus, it also acts as a protective barrier. It helps prevent harmful substances, such as certain toxins and pathogens, from reaching the developing baby.

Physical Protection: The placenta provides a cushioning effect, helping to protect the fetus from physical impact and pressure within the uterus.

97
Q

Components of the female reproductive system and their functions in relation to developing a fetus.

A

Ovaries:

Function: Ovaries produce eggs (ova) through a process called ovulation. These eggs are necessary for fertilization by sperm to initiate pregnancy.
Fallopian Tubes:

Function: Fallopian tubes are the pathways through which the egg travels from the ovary to the uterus. Fertilization typically occurs in the fallopian tubes when a sperm meets an egg.
Uterus (Womb):

Function: The uterus provides a safe and nurturing environment for a fertilized egg to implant and develop into a fetus. The inner lining of the uterus, called the endometrium, thickens in preparation for pregnancy. If pregnancy occurs, the fertilized egg attaches to the endometrium.
Cervix:

Function: The cervix is the lower part of the uterus that connects to the vagina. During pregnancy, the cervix forms a mucus plug to seal off the uterus and protect the developing fetus from infections.
Vagina:

Function: The vagina serves as the birth canal, allowing the baby to pass through during childbirth.
Amniotic Sac:

Function: The amniotic sac is a fluid-filled membrane that surrounds the developing fetus. It provides protection, cushioning, and a controlled environment for fetal growth and movement.
Placenta:

Function: The placenta is an organ that develops during pregnancy and serves as the connection between the mother and the fetus. It facilitates the exchange of nutrients, oxygen, and waste products between the maternal and fetal bloodstreams. The placenta also produces hormones crucial for maintaining pregnancy.
Amniotic Fluid:

Function: Amniotic fluid surrounds the fetus within the amniotic sac. It helps protect the fetus from physical impact, regulates temperature, supports lung development as the fetus “breathes” it in and swallows it, and allows for movement.
Umbilical Cord:

Function: The umbilical cord contains blood vessels that connect the fetus to the placenta. It serves as the conduit for the exchange of nutrients, oxygen, and waste products between the fetus and the mother.
Hormonal Changes:

Function: Hormonal changes within the female reproductive system, including hormones like estrogen and progesterone, prepare the body for pregnancy and help regulate the menstrual cycle and the changes that occur during pregnancy.

98
Q

endometrium etymology

The word “endometrium” is derived from two Greek roots: “endo,” which means “within,” and “metra,” which means “uterus.” Therefore, “endometrium” literally translates to “within the uterus.

A

Uterus etymology

ChatGPT
The word “uterus” also has its origins in Latin and can be traced back to the ancient Indo-European root “*udéro,” which meant “womb” or “belly.” In Latin, “uterus” specifically referred to the womb of a pregnant animal, and it eventually came to be used in the context of human anatomy to refer to the female reproductive organ where a fetus develops during pregnancy. The word has remained relatively consistent in its meaning throughout various languages and historical periods.

The word “uterus” can be translated to Arabic as “رحم” (rahim), which refers to the female reproductive organ where a fetus develops during pregnancy.

99
Q

Amniotic Fluid:

supports lung development as the fetus “breathes” it in and swallows it. Explain this to me. clarify it please

what does pocket mean in this cntext

ChatGPT
In the context of the Amniotic Fluid Index (AFI) measurement, a “pocket” refers to a localized area or space within the uterus that contains amniotic fluid. These pockets are measured to assess the amount of amniotic fluid present in the uterus during pregnancy. The AFI measurement involves measuring the depth of the largest amniotic fluid pockets to determine if the amniotic fluid levels are within the normal range.

A

Lung Development: While the fetus is in the womb, its lungs are not yet needed for breathing air. However, lung development is a crucial process that prepares the baby’s lungs for functioning outside the womb after birth.

“Breathing” Amniotic Fluid: Even though the fetus is surrounded by amniotic fluid within the amniotic sac, it doesn’t breathe in the same way we do. Instead, the fetus “practices” breathing by inhaling and exhaling amniotic fluid. This practice is essential for the development of lung muscles and tissues.

Swallowing and Excreting Amniotic Fluid: As the fetus “breathes” in amniotic fluid, it also swallows some of it. This process helps the fetus practice swallowing and digestion, which are important skills for after birth. The swallowed amniotic fluid is processed by the fetal kidneys, and some of it is excreted as urine into the amniotic fluid.

Exchanging Nutrients and Waste: The amniotic fluid contains a variety of substances, including nutrients and waste products. Through the process of swallowing and excreting amniotic fluid, the fetus engages in a type of internal recycling. Nutrients from the amniotic fluid are absorbed into the fetal bloodstream, and waste products are eliminated via urine.

Lung Maturation: In addition to the physical benefits of “breathing” and swallowing, the presence of amniotic fluid in the lungs also contributes to their maturation. The fluid helps the lungs develop the appropriate airway structure and surfactant production, which is a substance necessary for breathing air effectively.

100
Q

Amniotic Fluid Volume (AFV) vs The Amniotic Fluid Index (AFI). Give me key differences

Index= is in cm and helps to know the health of each quadrant and is more of an overall image of the fuild amount

A

Key Differences:

Measurement Method:

AFV: Measures the total volume of amniotic fluid in milliliters.
AFI: Measures the depth of the largest vertical pockets of amniotic fluid in centimeters.
Focus:

AFV: Provides a general assessment of the overall amount of amniotic fluid.
AFI: Focuses on the depth of specific amniotic fluid pockets to assess fluid levels.
Units:

AFV: Measured in milliliters (ml).
AFI: Measured in centimeters (cm).
Clinical Application:

AFV: Can indicate whether amniotic fluid levels are low (oligohydramnios) or high (polyhydramnios).
AFI: Used to determine if amniotic fluid levels are normal for the specific gestational age, aiding in assessing fetal well-being.
Evaluation of Fetal Well-Being:

AFV: Extreme deviations from the normal range can be associated with fetal growth restriction or other issues.
AFI: AFI values outside the normal range may suggest potential concerns about fetal well-being.

101
Q

when do we use Chorionic Villus Sampling (CVS) and when do we use Amniocentesis? How do we know which one to use if they both look for the same abnormalities

A

Chorionic Villus Sampling (CVS):

Timing: CVS is typically performed earlier in pregnancy, usually between the 10th and 13th weeks. This can provide earlier results compared to Amniocentesis.

Procedure: CVS involves collecting a small sample of chorionic villi, which are tiny finger-like projections on the placenta. These cells have the same genetic information as the fetus. The sample can be obtained through either transcervical (through the cervix) or transabdominal (through the abdomen) approaches.

Advantages: Early results can provide more time for decision-making in case the test indicates a genetic condition. It’s also advantageous in situations where there’s a need for earlier information due to medical reasons.

Amniocentesis:

Timing: Amniocentesis is typically performed later in pregnancy, usually between the 15th and 20th weeks.

Procedure: Amniocentesis involves withdrawing a small amount of amniotic fluid containing fetal cells and genetic material. The procedure is performed through the abdomen.

Advantages: It’s considered a safer procedure due to a lower risk of miscarriage compared to CVS. It can also provide more comprehensive information about the fetus’s overall health, as the amniotic fluid contains cells that shed from the fetus’s skin, urine, and respiratory tract.

Choosing between CVS and Amniocentesis depends on several factors:

Gestational Age: The stage of pregnancy is a critical factor. CVS is performed earlier, which might be beneficial in cases where early diagnosis is necessary.

Risk Tolerance: CVS has a slightly higher risk of miscarriage compared to Amniocentesis. Some individuals might prefer Amniocentesis due to its lower risk profile.

Medical Indications: Specific medical conditions or family history might influence the choice. For example, if a particular genetic condition is suspected due to family history, the choice might be guided by the most appropriate test to detect that condition.

Availability and Expertise: Not all medical centers offer both procedures, so availability might play a role in the decision.

Let’s say a pregnant woman is concerned about the possibility of her baby having a genetic disorder, such as Down syndrome. She wants to undergo a prenatal diagnostic test to get more information about the baby’s genetic makeup.

Example Scenario:

Gestational Age: The woman is currently at 12 weeks of pregnancy.

Concern: The woman is worried about the risk of Down syndrome due to her age and family history.

In this scenario, the woman could choose to undergo either CVS or Amniocentesis to obtain more information about the fetus’s genetic condition.

Option 1: Chorionic Villus Sampling (CVS):
Since CVS can be performed between the 10th and 13th weeks of pregnancy, it is an option for the woman in her 12th week. She could opt for CVS to get early results, which might provide her with more time to make decisions and plan if the test detects any genetic abnormalities.

Option 2: Amniocentesis:
Although Amniocentesis is also a valid option, it is typically performed between the 15th and 20th weeks of pregnancy. In this scenario, the woman might need to wait a few more weeks before undergoing Amniocentesis to get accurate results.

The choice between CVS and Amniocentesis would depend on the woman’s preferences, the timing of the procedure, and any additional medical considerations. If she values getting results earlier and is within the appropriate gestational age range, she might lean towards CVS. On the other hand, if she’s willing to wait a bit longer and prefers a procedure with a slightly lower risk of miscarriage, Amniocentesis could be her preferred choice.

102
Q

Timing ????

Chorionic Villus Sampling (CVS):

Amniocentesis:

A

BOTH LOOK FOR THE SAME THINGS

But one can be done before the other depending on what we suspect and how early we want to take measures :

Chorionic Villus Sampling (CVS): 10th and 13th weeks of pregnancy.

Amniocentesis: 15th and 20th weeks of pregnancy.

103
Q

Cell-Free DNA Testing

is a type of Maternal Assays

A

Percutaneous etymology

“Per-“: This is a Latin prefix meaning “through” or “by means of.”

“Cutaneous”: This comes from the Latin word “cutis,” which means “skin.” The suffix “-ous” indicates “pertaining to” or “characterized by.”

So, “percutaneous” literally means “through the skin.

104
Q

IUP?

A

intrauterine pregnancy meaning

An intrauterine pregnancy (IUP) refers to a pregnancy in which the fertilized egg, or embryo, has successfully implanted and is developing within the uterus. In other words, it is a normal pregnancy in which the embryo attaches itself to the lining of the uterus and grows there as it develops into a fetus.

105
Q

vertex presentation meaning ?

Vertex presentation refers to the fetal position within the uterus during pregnancy or labor, where the baby’s head is positioned to emerge first through the birth canal during childbirth. In other words, the baby is oriented with its head down and its body aligned in a way that facilitates a smooth passage through the birth canal.

During vertex presentation, the baby’s head is the presenting part that enters the pelvis first. This is the most common and preferred position for childbirth, as it is associated with a lower risk of complications during delivery. In a vertex presentation:

The baby’s head is in contact with the cervix and is closest to the birth canal.
The baby’s buttocks are positioned higher in the uterus, away from the cervix.
The back of the baby’s head (occiput) is typically positioned to face the mother’s front side (anterior position), which is generally the ideal position for childbirth.
An accurate assessment of the baby’s presentation is usually done through ultrasound or manual examination by a healthcare provider. Vertex presentation is considered optimal for a vaginal delivery, as it allows for the baby’s head to dilate and efface the cervix during labor, facilitating the birthing process. However, it’s important to note that sometimes the baby’s position can change during labor, and healthcare professionals are trained to manage various presentations to ensure a safe delivery.

A
106
Q

Phosphatidylglycerol (PG):
Phosphatidylglycerol is another component of surfactant, and its presence in the amniotic fluid is an indicator of fetal lung maturity.

Presence of PG: The presence of phosphatidylglycerol in the amniotic fluid is a positive sign of fetal lung maturity. It suggests that the fetal lungs are producing surfactant, which is crucial for proper lung function after birth.

A
106
Q

Chorionic Villus function

so is it near the placenta ?

Yes, the chorionic villi are located within the placenta

A

Nutrient Exchange: Chorionic villi are involved in nutrient and gas exchange between the mother’s bloodstream and the developing fetus. Small blood vessels within the villi allow for the transfer of oxygen, nutrients (such as glucose and amino acids), and other essential substances from the mother’s blood to the fetal blood. Conversely, waste products like carbon dioxide are transported from the fetal blood to the maternal blood for elimination.

Hormone Production: The chorionic villi are responsible for producing important hormones during pregnancy. One of the most well-known hormones produced by the placental tissue within the chorionic villi is human chorionic gonadotropin (hCG). This hormone is crucial for maintaining the corpus luteum in the ovary, which produces progesterone during the early stages of pregnancy.

Immunological Barrier: Chorionic villi play a role in protecting the developing fetus from the maternal immune system. While the placenta’s function is to allow selective exchange of substances, it also acts as a barrier that prevents the mother’s immune cells from attacking the fetus as a foreign entity.

Waste Removal: The chorionic villi help transport waste products from the fetal circulation to the maternal circulation. This waste, including carbon dioxide and other metabolic byproducts, is then eliminated from the mother’s body through her own excretory systems.

Structural Support: Chorionic villi provide structural support to the developing placenta, which is essential for maintaining proper attachment to the uterine wall. This attachment ensures the placenta’s stability and effective nutrient and gas exchange.

Formation of Placenta: The chorionic villi, along with other fetal and maternal tissues, contribute to the formation of the placenta. The placenta is a complex organ that develops during pregnancy to facilitate the exchange of nutrients, waste products, and gases between the mother and the fetus.

107
Q

Misoprostol: Misoprostol is a medication that can be used to induce contractions and help expel the contents of the uterus after a miscarriage. It’s often used as an alternative to surgical procedures, especially in cases of incomplete or missed abortion.

A

not the same as oxytocin

107
Q

Dilation and Curettage vs Dilation and Evacuation . Give me a couple key differances

D&C: D&C is often used in the early stages of pregnancy (within the first trimester) for various reasons, including diagnostic procedures and managing incomplete miscarriages.
D&E: D&E is typically performed later in the first trimester or early in the second trimester, when the pregnancy has advanced further. It’s commonly used for pregnancy termination.

A
108
Q

Recommended Method of Dating:
Ultrasound is one of the most accurate methods for determining gestational age. When is it most accurate ?

A

Most Accurate Between 14-22

109
Q

An ectopic pregnancy is a potentially life-threatening condition in which a fertilized egg implants and grows outside of the uterus, most commonly in one of the fallopian tubes. Since the fallopian tubes are not designed to support the growth of a developing embryo, an ectopic pregnancy can lead to various complications, including the rupture of the fallopian tube because with time the baby becomes too big for them to handle causing internal bleeding.

The most common symptom of an ectopic pregnancy is abdominal pain, often accompanied by vaginal bleeding. Other symptoms might include shoulder pain (caused by internal bleeding irritating the diaphragm), dizziness or fainting (due to blood loss), and gastrointestinal symptoms.

Ectopic pregnancies can’t progress normally, and they are not viable. If left untreated, they can lead to serious complications, including severe bleeding, shock, and even death. Therefore, early detection and intervention are crucial.

A

.

110
Q

Progesterone and cervix as well as the pregnancy overall

Cerclage etymology

The term “cerclage” is derived from the French word “cercler,” which means “to encircle” or “to put a ring around.” In the medical context, a cerclage is a surgical procedure in which a stitch or suture is placed around the cervix to provide support and prevent premature dilation. The term “cerclage” aptly describes the action of encircling or putting a “ring” of suture material around the cervix to reinforce it and prevent it from opening too soon during pregnancy.

A

Progesterone supplementation might be recommended to help maintain the integrity of the cervix and prevent further dilation.
Progesterone is a hormone that plays a crucial role in supporting pregnancy and maintaining the uterine environment.

111
Q

Prophylactic Cerclage when is it done ?

A

11-15 w

112
Q

what does dilating prematurely mean in cervix ? can you use laymens terms to explain it to someone with no education

Of course, I’d be happy to help explain this in simple terms!

Imagine the cervix as a doorway that leads from a woman’s uterus to the outside world. When a baby is ready to be born, the cervix needs to open up, just like a door needs to open for someone to come through. This opening process is called “dilating.”

Now, “dilating prematurely” means that the cervix starts opening up too soon, before the baby is fully developed and ready to be born. It’s like the door to the baby’s home (the uterus) is trying to open before the baby is big enough and strong enough to come out safely.

Premature dilation of the cervix can be a concern because it might lead to the baby being born too early, which can bring some health risks for both the baby and the mother. Doctors keep a close watch on this situation to make sure the baby stays safe and grows as much as possible before being born. They might use medical treatments or procedures to help prevent the cervix from opening too soon until the baby is fully ready to come into the world.

A
113
Q

Calcium Gluconate Availability: Calcium gluconate is the antidote for magnesium sulfate toxicity

A
114
Q

Classification of Abruption

A

The classification of placental abruption, based on the extent of placental separation and associated bleeding, helps healthcare providers assess the severity of the condition. Here’s a breakdown of the abruption classification:

Grade 0:
IT WENT UNnOTICED AND CAUSED NO PROBLEMS. THIS is why we could not see it until after delivery.
Diagnosis is made from observation of the afterbirth (placenta) after delivery.
There may be no overt signs of abruption during pregnancy or labor, but the presence of retroplacental clot or hematoma is detected after birth.
Grade 1:

No vaginal bleeding may be evident.
Placental separation is about 10%, indicating a mild degree.
Blood loss is typically less than 500 ml.
Maternal and fetal conditions may remain stable.
Grade 2:

Bleeding might range from absent to moderate.
Placental separation is around 20-50%, indicating a moderate degree.
Blood loss is between 1000 to 1500 ml.
This grade can be associated with more significant symptoms and potential complications.
Grade 3:

Bleeding might range from absent to moderate.
Placental separation is greater than 50%, indicating a severe degree.
Blood loss is more than 1500 ml.
This is the most severe form of placental abruption and is associated with substantial maternal and fetal risks.

115
Q

chorionic gonadotropin (hCG). This hormone is crucial for maintaining the corpus luteum in the ovary, which produces progesterone during the early stages of pregnancy.

A

Chorionic gonadotropin (hCG) is a hormone produced by the placenta after getting pregnant. it maintains the corpus luteum in the ovary and therefor helps produce progesterone

116
Q

Immunological Barrier: Chorionic villi play a role in protecting the developing fetus from the maternal immune system. They are within the placenta.

A

acts as a barrier that prevents the mother’s immune cells from attacking the fetus as a foreign entity.

117
Q

so preeclampsia does not always lead to HELLP SYNDROME ?

A

oui

118
Q

Type 1 Diabetes:

Cause: Type 1 diabetes is an autoimmune condition where the body’s immune system attacks and destroys the insulin-producing cells in the pancreas. This results in little to no insulin production.
Onset: It often develops in childhood or early adulthood, but it can occur at any age.
Insulin Dependence: People with type 1 diabetes are dependent on insulin injections or an insulin pump to manage their blood sugar levels.
Symptoms: Symptoms can develop quickly and include excessive thirst, frequent urination, unexplained weight loss, fatigue, and increased hunger.
Risk Factors: Genetic predisposition and environmental factors may contribute to its development.
Treatment: Insulin therapy is the primary treatment. Blood sugar monitoring, carbohydrate counting, and a balanced diet are crucial for managing blood sugar levels.
Type 2 Diabetes:

Cause: Type 2 diabetes involves insulin resistance, where cells do not respond effectively to insulin, and the pancreas might not produce enough insulin to meet the body’s needs.
Onset: It typically develops in adulthood, but it’s increasingly seen in children and adolescents due to rising obesity rates.
Insulin Dependence: While some people with type 2 diabetes can manage their condition with lifestyle changes and oral medications, others may eventually require insulin.
Symptoms: Symptoms may develop gradually and include increased thirst, frequent urination, fatigue, blurred vision, slow wound healing, and frequent infections.
Risk Factors: Risk factors include obesity, sedentary lifestyle, family history, age, and certain ethnic backgrounds.
Treatment: Lifestyle modifications (diet and exercise) are key components. Oral medications, injectable medications, and insulin might be prescribed to control blood sugar levels.
Key Differences:

Type 1 diabetes is an autoimmune disorder with no known prevention, while type 2 diabetes is often associated with lifestyle factors and can sometimes be prevented or delayed through healthy habits.
Type 1 diabetes requires insulin from the start, whereas type 2 diabetes might initially be managed without insulin.
Type 2 diabetes is more common and accounts for the majority of diabetes cases globally.
Genetic factors play a significant role in type 1 diabetes, while both genetic and environmental factors contribute to type 2 diabetes.

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beta cells. These cells are located in clusters called the islets of Langerhans within the pancreas. Beta cells play a crucial role in maintaining blood sugar (glucose) levels by producing and releasing insulin into the bloodstream.

Insulin is a hormone that helps regulate glucose metabolism. It facilitates the uptake of glucose by cells throughout the body, allowing them to use glucose as a source of energy. When blood sugar levels rise after eating, beta cells respond by releasing insulin, which helps lower blood glucose levels by promoting its uptake into cells.

Type 1 Diabetes: Around 5-10% of all diabetes cases are classified as type 1 diabetes. It is less common and often develops in childhood or early adulthood.

Type 2 Diabetes: The vast majority of diabetes cases, around 90-95%, are classified as type 2 diabetes. It is more common and typically develops in adulthood, although it is increasingly being diagnosed in younger individuals due to rising rates of obesity and sedentary lifestyles.

118
Q

One potential cause of oligohydramnios is indeed improper functioning of the fetus’s kidneys. The kidneys play a vital role in producing and maintaining amniotic fluid. If the fetal kidneys are not functioning properly, they may not produce enough urine, which is a significant component of amniotic fluid. This can lead to a decreased fluid volume in the amniotic sac.

Other factors that can contribute to oligohydramnios include:

Maternal dehydration: Inadequate maternal hydration can lead to reduced amniotic fluid levels.

Fetal abnormalities: Certain fetal abnormalities, including kidney or urinary tract issues, can impact the production of urine and, subsequently, amniotic fluid.

Placental insufficiency: If the placenta is not functioning optimally, it can affect the transfer of nutrients and oxygen to the fetus, potentially leading to decreased urine production and oligohydramnios.

Post-term pregnancy: In pregnancies that extend beyond the due date, the amniotic fluid levels may decrease naturally.

Rupture of membranes: If the amniotic sac ruptures (water breaks) before labor begins, it can result in a gradual reduction of amniotic fluid over time.

Maternal medical conditions: Conditions such as high blood pressure (preeclampsia) or diabetes can sometimes be associated with oligohydramnios.

Twin-to-twin transfusion syndrome: In pregnancies with identical twins sharing a placenta, imbalanced blood flow between the twins can lead to changes in amniotic fluid levels.

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119
Q

Amniotic Fluid and Movement: The amniotic fluid surrounding the fetus serves multiple purposes, one of which is providing a protective environment that allows the baby to move. As the fetus grows and develops, it begins to move its limbs within the amniotic fluid. These movements are essential for proper musculoskeletal development.

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120
Q

Tocodynamometr

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aparato que mide la fuerza de las contracciones

121
Q

Uteroplacental insufficiency (UPI) vs IUGR ?

insufficient O2 = less growth

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Uteroplacental Insufficiency (UPI):
UPI refers to a condition where there is inadequate blood flow and oxygen delivery from the mother’s uterus to the placenta, which subsequently affects the supply of nutrients and oxygen to the developing fetus
Intrauterine Growth Restriction (IUGR):
IUGR refers to a condition where the fetus does not grow at the expected rate during pregnancy. It can occur for various reasons, including genetic factors, maternal health issues, placental problems, and more. UPI is one potential cause of IUGR.