Maternal medicine TOGs Flashcards
Dose of glucocoticoids if sick
- Double the dose
Fasting rules for steroids in adrenal disease
- Give IM hydrocortisone
Management of gluco/mineralocorticoids in labour
- Hold fludrocortisone
- Give Hydrocortisone
TB rate in UK
6.9/1000
Testing for TB
Skin tests:
- Tine or Mantoux
- High flase positive- BCG vac, lymphoma etc
C-TB- less false positive
If skin test +, sputum culture:
- Ziehl–Neelsen staining of sputum
- Lowenstein–Jensen medium for culture
Other tests
- CXR once diagnosed
- Ghon’s focus- granuloma reaction
Treatment for TB
- Isoniazid, Rifampicin, pyrazinamide, ethambitol
GIVE pyridoxine 10mg with isoniazid to prevent nuerotoxicity
HF risk with mitral stenosis
- 33% risk if moderate MS
- 50% risk if severe MS
Cardiac conditions of HIGH risk in preg
- Severe MS- valve area <1cm
- Marfans w Aortic dilation >45mm
- Pulmonary HTN
- LVEF <30%
- Prev peripartum cardiomyopathy w residual LV impairment
Peak levels of anti-Xa level
1.0-1.2IU/ml
Uterotonics for PPH in heart disease
- First line- oxytocin
DO NOT USE ERGOmetrine - 2nd line- Misoprostol or oxytocin infusion or carboprost
Avoid carboprost if pulmonary HTN
When does peripartum cardiomyopathy develop?
- Mostly 4 months PN
or
1 month pre-delivery
Diagnosis of PPCM
- ECHO, EF<45%
- BNP >100
- ECG- non specific
Mx of PPCM
- ACEi/ARB
- MDT approach
- LMWH
- Bromocriptine-
2.5mg OD 1 week, EF>25% - If EF <25% 2.5mg BD 2 weeks to stop lactation.
Prognosis for PPCM
- 50-80% women get LVEF >50%
- high risk of relapse - 50% chance of LVEF drop in next preg