Maternal Disease in Pregnancy

Question 1

Diabetes - Effects on Foetus 5

Answer 1

Risk of congen mal
Perinatal mort
Macrosomia "cherub babies"
Shoulder dys
Polyhydramnios

Question 2

Diabetes - Effects on Mother 5

Answer 2

Diabetic neph
Diabetic retin
Risk miscarriage
Risk pre-ecl
Risk operative deliv

Question 3

Diabetes - Management 4

Answer 3

Increased insulin
Orals usually avoided
Strict control
IOL @ 38-39/40 is norm

Question 4

Epilepsy - Effects on Foetus 4

Answer 4

Teratogenicity
Risk NTDs
Orofacial clefts
Heart defects

Question 5

Epilepsy - Effects on Mother

Answer 5

Most unaffected

Question 6

Epilepsy - Management 3

Answer 6

Folic Acid 5mg OD for NTDs
Medication continued usually
Vit K from 36wks to prevent HDN

Question 7

Anaemia - Effects on Foetus 2

Answer 7

LBW

Preterm deliv

Question 8

Anaemia - Effects on Mother 1

Answer 8

PPH risk

Question 9

Anaemia - Management 2

Answer 9

FBC @ booking and 28/40

Treat cause

Question 10

Hypothyroidism - Effects on Foetus 2

Answer 10

Developmental delay if hypo severe

Foetal thyrotoxicosis if second to Grave’s

Question 11

Hypothyroidism - Effects on Mother ()

Answer 11

Levothyroxine dose change

Question 12

Hypothyroidism - Management 2

Answer 12

Aim to continue on pre-pregnancy dose of levothyroxine

TFTs in each trimester and adjust dose

Question 13

Asthma - Effects on Foetus if severe 3

Answer 13

If severe:
Perinatal morbidity
Perterm
IUGR

Question 14

VTE - Effects on Foetus

Answer 14

Thrombophilia - APLS —> pregnancy loss, IUGR

Question 15

VTE - Effects on Mother

Answer 15

Leading cause of maternal death

Question 16

VTE - Management

Answer 16

LWMH for those with DVT/PE

Prophylaxis for risk factors or following CS