Mass Transport in Animals Flashcards
how many polypeptide chains is haemoglobin made up of?
4
what structure does haemoglobin have?
quaternary
what does each polypeptide chain have?
a haem group containing Fe2+
what does the heam group on the polypeptide do?
binds to an oxygen molecule
what is the equation showing the formation of oxyhaemoglobin?
oxygen + heamoglobin ⇌ oxyhaemoglobin
what is partial pressure?
a measure of the concentration of oxygen present in tissues
what is loading (association)?
when oxygen is taken up by haemoglobin
what is unloading (dissociation)?
when oxygen is released by haemoglobin
what does affinity mean?
how well the oxygen is bound to the haemoglobin
what is percentage saturation?
the amount of oxygen combined with haemoglobin
what is the equation to calculate percentage saturation?
oxygenated haemoglobin/maximum saturation X 100
number of binding sites occupies by oxygen/maximum number of binding sites X 100
where does oxygen load?
lungs
why does oxygen load at the lungs?
high partial pressure of oxygen
haemoglobin has a high affinity for oxygen
haemoglobin becomes saturated with oxygen
where does oxygen unload?
respiring tissues
why does oxygen unload at respiring tissues?
low partial pressure of oxygen
haemoglobin has a low affinity for oxygen
haemoglobin becomes less saturated with oxygen
why is an oxygen dissociation curve sigmoid?
when the first oxygen binds to the first haem group, the tertiary and quaternary structure of the haemoglobin change uncovering the next haem group so oxygen can bind more easily
what is the Bohr effect?
the oxygen dissociation curve shifting to the right
why does the oxygen dissociation curve shift to the right?
the partial pressure of oxygen at the respiring tissues is low so haemoglobin dissociates from the oxygen so it can be used for aerobic respiration
what does increased CO2 in the blood cause?
increased blood acidity alters the tertiary structure of haemoglobin
why does the oxygen dissociation curve shift to the left for species living at high altitudes or in the bottom of lakes?
there is less oxygen available so normal haemoglobin wouldn’t be fully saturated
why does the oxygen dissociation curve shift to the right for species with a high metabolic rate?
haemoglobin unloads oxygen much quicker
why does the fetal haemogobin curve shift to the left?
it has a higher affinity for oxygen
oxygen from the mother loads onto the fetal haemoglobin
allows for aerobic respiration
what are the features of a heart?
aorta
pulmonary artery
pulmonary vein
left atrium
atrioventricular valve
left ventricle
right ventricle
semi-lunar valve
right atrium
vena cava
why does the left ventricle have a thicker muscular wall than the right ventricle?
left ventricle has to contract more forcefully to generate a high blood pressure to transport blood around the whole body
what is the function of valves?
prevent the backflow of blood
what is the function of the atrioventricular valve?
prevents the backflow of blood into the atria
what is the function of the semi-lunar valve?
prevents the backflow of blood into the ventricles