mass transport Flashcards
why is the dissociation curve Sigmoidal s shaped?
co-operative binding=
-low partial pressures of O2 haemoglobin has low affinity for O2, doesnt load as readily
-as O2 partial pressures increase affinity of haemoglobin increases. when first O2 molecule loads, changes shape of haemoglobin moleucle =easier
-difficult to become 100% saturated - hard to diffuse and associate into 4th
describe haemoglobin in low oxygen environments
-Hb has higher affinity for O2
-Hb loads more readily at low pO2
-curve shifts to left
describe haemoglobin with high activity levels
-very active
-aerobically respire faster
-need more O2 per unit mass of tissue
-Hb has lower affinity for O2
-Hb unloads more readily at any given pO2
-curve shifted to the right
describe haemoglobin in smaller organisms
-higher SA:V
-transfer heat energy to environment faster
-aerobically respre faster/high metabollic rate
-need more O2 per unit mass of tissue
-Hb loads more readily at any given pO2
-curve shifts to the right
where does the renal artery carry blood from and to?
aorta to kidney
why is the left venticle much thicker?
need to contract more powerfully to pump oxygenated blood around the body
whats the importance of the septum?
separates sides so oxygenated and deoxygenated blood dont mix
also enables different pressures
whats the hearts own blood supply?
coronary arteries
in blood vessels how can blood flow be controlled?
in arterioles
-when muscle relaxes
arterioles dilate
-lumen become wider
-blood flow increases
-when muscle contracts
arterioles constrict
-lumen narrows
-blood flow decreases
what are the 3 stages of the cardiac cycle?
- ventricles relax, atria contract
- ventricles contract,atria relaxes
3.ventricles relax, atria relax
when do atrioventricular valves open?
when pressure in the atria is greater than the ventricles
when do semilunar valves open?
when pressure is higher in the arteries than in the aorta/pulmonary artery
whats the formula for cardiac cycle?
stroke volume x heart rate
define stroke volume
vol of blood pumped during each heart beat in cm3
give 3 examples of contents of plasma
hormones
fatty acids
amino acids
whats the role of tissue fluid?
transport oxygen and nutrients from blood to cells and CO2 and other waste products from cells back to blood
where does formation of tissue fluid occur?
at a capillary network which surrounds cells
how is tissue fluid formed?
at arteriole end:
-blood has higher hydrostatic pressure (due to left ventricle) lower osmotic pressure
-water is forced out of fenestrations
-along with dissolved substances like oxygen and glucose
what is ultrafiltration?
filtration under pressure
how is fluid returned to the capillary?
at venous end:
-blood has lower hydrostatic pressure
-plasma protiens lower water potential
in blood
-higher hydrostatic pressure
-water moves back in by osmosis
other waste by diffusion
-excess tissue fluid moves into lymphatic capillaries where it drains back into circulatory system via subclavian vein
importance of the lymphatic system
-draining excess tissue fluid and returning to blood
-for immune system = lymph nodes produce lymphocytes
-absorp lipids from digestive system into lacteal