Marrow 2a SBA mock Flashcards
He has been having non-bloody diarrhoea over the past 24 hours, and his stool sample has tested positive for Clostridium Difficile Toxin (CDT). On examination, his abdomen is soft, tender in the left-iliac fossa, with no signs of peritonism.
Which antibiotics would be most appropriate for this patient?
IV Metronidazole + oral Vancomycin
Which clinical feature is a risk factor for sudden cardiac death?
Unexplained syncope
Hypertrophic cardiomyopathy
An 85 year old lady has been admitted for a stage 2 acute kidney injury (AKI) secondary to dehydration. She has a past medical history of type 2 diabetes, ischaemic heart disease and osteoarthritis.
Which of the following medications should be held while she recovers?
Metformin
What mechanism explains how most new strains of influenza emerge over time?
Antigenic drift
What is the mechanism of dehydration in cholera?
Reversal of the concentration gradient of ions
What is the mechanism of action of clindamycin?
Inhibits bacterial protein synthesis by binding 50S ribosomal subunit
A diagnosis of colorectal cancer is suspected. Which is the best investigation to confirm this diagnosis?
A colonoscopy
A 35-year-old male presents with a lump in his groin that has been increasing in size over the past few weeks. Physical exam reveals a tender, mobile lump in the inguinal region which is reducible. Which is the most likely diagnosis?
Inguinal hernia
Which Toll Like Receptor is activated by flagellated bacteria to trigger an immune response?
TLR5
A 36-year-old woman attends A&E with prolonged and severe gastroenteritis. She has no known past medical history. Routine blood tests are taken and show: Haemoglobin 108, MCV 102, platelets 555 (150-450). A blood film demonstrates Howell-Jolly bodies, target cells and acanthocytes.
Which is the most likely cause of these results?
Coeliac
