mar 26 Flashcards

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1
Q

what is dextromethorphan?

A

a cough suppressant

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2
Q

what may dextromethorphan test positive for on drug screen?

A

PCP

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3
Q

beta blockers may cause a false positive drug screen for which drug?

A

amphetamines

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4
Q

A patient started on risperidone has akathisia, what is the first step in management?

A

dose-reduction

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5
Q

what triggers reactive attachment disorder?

A

it occurs in children when the normal developmental process of emotional bonding is interrupted by inconsistent or inadequate care

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6
Q

clinical features of reactive attachment disorder

A
  • child does not seek or respond to comfort
  • poor social responsiveness, limited positive affect
  • unexplained irritability/fear/sadness

-may have toileting/sleep difficulties

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7
Q

management of reactive attachment disorder?

A
  • safe, stable and enriching environment
  • consistent, responsive caregiving
  • psychological services
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8
Q

which opioids will not be detected on a standard drug urine screen?

A

semisynthetic or synthetic opioids (fentanyl, methadone, tramadol, oxycodone)

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9
Q

why are synthetic opioids not detected on a standard urine drug screen?

A

because standard drug screen detects breakdown products or natural opioids - detects morphine

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10
Q

how long is an adequate antidepressant trial?

A

4-6 weeks

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11
Q

first line treatment for acute stress disorder?

A

trauma focused CBT -

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12
Q

If a patient with acute stress disorder doesnt want to go to therapy, what is the best initial approach in treating them?

A

provide education common physical and emotional stress responses

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13
Q

pathophysiology of tardive dyskinesia

A

dopamine D2 receptor upregulation and supersensitivity resulting from chronic blockade of dopamine receptors

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14
Q

should chlordiazepoxide be used in a patient with liver disease?

A

No - it has a long half life and active metabolites that can lead to toxicity in patients with liver disease

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15
Q

which benzos can be used to treat alcohol withdrawal in patients with liver disease?

A

lorazapam, oxazepam, temazepam

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16
Q

why are lorazapam, oxazepam, temazepam preferred for patients with liver disease ?

A

they lack active metabolites and undergo hepatic metabolism via phase II glucoronidation

17
Q

clinical features of TCA overdose?

A

mental status changes, seizures, tachycardia, cardiac conduction delay, anticholinergic effects

18
Q

how do you treat prolonged QT interval in TCA overdose?

A

sodium bicarb