MAP regulation Flashcards
Carotid sinus innervation
Sinus n of herring —> glossopharyngeal n
Aortic sinus innervation
Aortic n —> vagus n
NTS
Located in brain stem, receives and coordinate peripheral signals
Both sinuses travel here
Dorsal motor nucleus of the vagus and nucleus ambiguus
Parasympathetic activity associated w/ CV function
Rostrum ventrolateral medulla
Sympathetic activity associated w/ CV function
Which sinus will response to a decrease in pressure?
The carotid sinus
What carries out long term adjustment of MAP?
Renin-Angiotensin II-Aldosterone system (RAAS)
Controls BP by regulations blood volume
Renin
Stimulated by B1 adrenergic activation
Causes angiotensinogen to convert to angiotensin I in he blood
Angiotensin I is converted to angiotensin II in the lung by ACE and will begin compensation
What secretes renin
Juxtaglomerular cells in the walls of afferent arterioles
Angiotensin II and its role in RAAS
Causes secretion of aldosterone from adrenal cortex
Stimulates secretion of ADH to increase fluid retention
Causes vasoconstriction by binding specific receptors to increase TPR and BP
Aldosterone in RAAS
Increases Na+ and H2O retention by the kidney and will increase BP, preload, CO, and therefore BP
Vasopressin
ADH
Acts on V1 (smooth muscle and V2 receptors to increase TPR and water retention
Natriuretic peptide
Causes arteriolar dilation, increases fluid loss, and inhibits renin
Helps decrease BP