MAP HW #14 - Skeletal Muscle (microscope anatomy & physiology) Flashcards
What is the insertion for the anterior fibers of the deltoid muscle?
Deltoid tuberosity of the humerus
The prefix ____ means flesh.
Sarco-
The prefix ____ means turning, change, or affinity for.
Tropo-
The prefix ____ means equal or same.
Iso-
The prefix _____ means abnormal, or diseased.
Dys-
The prefix _____ means muscle.
Myo-
During an exercise where muscles do not shorten, _____, contractions have occurred.
Isometric
________ is a missing protein in Duschenne 19s muscular dystrophy.
Dystrophin
The two proteins directly involved in muscle contraction are broadly called _______.
Myofilaments
The cell membrane of a muscle fiber is the ______.
Sarcolemma
__________ has an affinity for myosin binding sites in the absence of calcium.
Tropomyosin
Necrotizing fasciitis is a serious bacterial infection. Necrosis is the death of tissues in the body. Considering the organization of the connective tissue sheaths of skeletal muscle, explain how this infection could spread rapidly throughout the body.
Necrotizing fasciitis spreads quickly because the connective tissue sheaths, particularly the epimysium, are all continuous with each other and with the superficial fascia, so there are no physical barriers to stop the spread of the bacteria.
The bacterium Clostridium botulinum secretes botulinum toxin, a neurotoxin. The toxin blocks the release of acetylcholine from the axon terminal of a motor neuron. Explain how the toxin binding would change the normal sequence of events at the neuromuscular junction.
Botulinum toxin binds to the motor neuron and prevents the acetylcholine from being released into the synaptic cleft. This prevents the initiation of an end-plate potential because there is no neurotransmitter to bind to the ion-channel receptor on the muscle cell motor end plate.
Why are repeat injections of Botox® required over time to control blepharospasm?
PNS motor nerves regenerate
Botox® injection directly inhibits which process leading to acetylcholine (ACh) release?
Exocytosis