Management Flashcards
What is the gold standard investigation for bacterial STIs?
Culture from urethral/rectal smear
What is the gold standard investigation for TB?
3 Sputum Samples
Ziehl-Neelson Stain
Lowenstein-Jensen Medium
What is the gold standard diagnostic test for Acromegaly?
OGTT
What is the gold standard investigation for Coeliac?
Upper GI endoscopy and distal duodenal biopsy
What is the gold standard investigation for food/drug allergy?
Double-Blind Oral Challenge
What is the gold standard investigation for breast cancer?
Histopathology
What is the first line treatment for Hospital-Acquired Pneumonia?
Ciprofloxacin + Vancomycin
What is the treatment for severe HAP?
Tazocin + Vancomycin
What is the treatment for aspiration pneumonia?
Tazocin + Metronidazole
What is the treatment for CURB 0/1 CAP?
Amoxicillin
What is the treatment for CURB 2 CAP?
Amoxicllin
Clarithromycin
What is the treatment for CURB 3-5 CAP?
Co-Amoxiclav
Clarithromycin
What is the first line management for Minimal Change disease?
Steroids
What is the second line management for Minimal Change Disease?
Cyclosporin
What is the first line agent for CMV?
Ganciclovir
How is EBV managed?
Supportive
How is VZV managed?
Aciclovir
How is HSV managed?
Aciclovir
What is the first line management for myeloma?
Bortezomib
How is Salmonella treated?
Ceftriaxone
How is Campylobacter treated?
Erythromycin/Ciprofloxacillin
How is Listeria treated?
Ampicillin
How are Entamoeba histolytica/Giardia lamblia treated?
Metronidazole
How is Cryptosporidium Parvum managed?
Paromomycin
When would you consider transfusing red blood cells?
<70 if asymptomatic
<80 if symptomatic
How is Dengue Fever managed?
Supportive
How is DKA managed?
A to E
0.9& Saline
Fixed rate IV insulin after fluids
Monitor Glucose & K+
How is HHS managed?
A to E
0.9% Saline
Fixed rate IV Insulin
How would you manage a surgical wound infection with Staph a?
Fluclox
How is syphilis treated?
Single dose IM Benzylpenicillin
How is TB treated?
Rifampicin
Isoniazid
Pyrazinamide
Ethambutol
How is cryptococcal meningitis treated?
Amphotericin B
How would you manage MGUS/Smouldering Myeloma?
No treatment needed
How would you treat gonorrhoea?
IM Ceftriaxone
What are the 5 steps for suspected Diabetes Insipidus?
Glucose K Ca Plasma/Urine Osmolality 8 Hour water deprivation test
How is nephrogenic diabetes insipidus treated?
Thiazide Diuretics
What is the only curative treatment for myelofibrosis?
Stem Cell Transplant
How is HIV treated in pregnancy?
Zidovudine (NRTI)
How is Digoxin toxicity treated?
Digibond
How would you treat hypokalaemia 3.0-3.5?
Oral KCl
How would you treat Hypokalaemia <3.0?
IV KCl
When would you treat Hyperkalaemia?
> 5.5 and ECG changes
>6.5 regardless
How would you treat Hyperkalaemia?
Calcium Gluconate Dextrose + Insulin Nebulised Salbutamol Maybe Calcium Resonium Treat Cause
How would you treat Carcinoid Syndrome?
Octeotride (Somatostatin Analogue)
Which factors’ synthesis is inhibited by Warfarin?
2,7,9,10
C,S,Z
Which factors does heparin inhibit?
Thrombin
9,10,11
How would you manage someone with Vitamin K Deficiency who is acutely haemorrhaging?
Fresh Frozen Plasma
How might Myasthenia Gravis be treated?
Neostigmine
Which drugs may be used to treat small/medium vessel vasculitides?
Corticosteroids
Cyclophosphamide
How is Hodgkin’s Lymphoma treated?
ABVD Adriamycin Bleomycin Vinblastine Dacarbazine
How is chronic granulomatous disease treated?
IFN-gamma
How is AML treated?
Daunorubicin
Cytarabine
Which drug targets diseases with a (9;22) translocation?
Imatinib
How is Burkitt’s Lymphoma treated?
Rituximab (Anti-CD20)
How is Acute Rheumatic fever treated?
Benzylpenicillin
Name one agent which may be used in the treatment of Sideroblastic Anaemia?
Pyridoxine
How is Addison’s Treated?
Hormone replacement
How is Haemochromatosis treated?
Venesection
Desferrioxamine
How is Wilson’s treated?
Zinc + Trientine > Penicillamine
How might Multiple Sclerosis be treated?
Corticosteroids
Interferon Beta
Natalizumab
How might you manage Goodpasture’s?
Plasmapheresis
How would you manage Kostmann Syndrome?
Colony stimulating factor